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T41011Azido-PEG6-CH2COOH；Azido-PEG6-CH2COOHAzido-PEG6-CH2COOH；Azido-PEG6-CH2COOH
Azido-PEG6-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T41011产 地：中国大陆
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T41010Maleimide-C10-NHS esterMaleimide-C10-NHS esterMaleimide-C10-NHS ester
Maleimide-C10-NHS ester is an alkyl/ether-based linker for PROTAC synthesis.
价 格：￥电议型 号：T41010产 地：中国大陆
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T4101SC-560；化合物SC560SC560；SC560
SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.
价 格：￥电议型 号：T4101产 地：中国大陆
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T4079LY-294002 hydrochloride；化合物LY-294002 hydrochlorideSF 1101|||LY 294002|||NSC 697286；SF 1101|||LY 2940
LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation.
价 格：￥电议型 号：T4079产 地：中国大陆
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T40101(±)-1,2-Diolein；甘油1,2-二油酸酯1,2-Dioleoyl-rac-glycerol；1,2-Dioleoyl-rac-glycerol|||甘油1,2-二油酸酯
(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.
价 格：￥电议型 号：T40101产 地：中国大陆
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T39507Fosgonimeton；FosgonimetonATH-1017；ATH-1017
Fosgonimeton is a hepatocyte growth factor receptor agonist (WO2017210489).
价 格：￥电议型 号：T39507产 地：中国大陆
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T39479Rovanersen；RovanersenWVE-120101|||Rovanersen；WVE-120101|||Rovanersen
Rovanersen (WVE-120101) is an antisense oligonucleotide that can be used for huntington’s disease research.
价 格：￥电议型 号：T39479产 地：中国大陆
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T39347RG-101；RG-101RG-101
RG-101 is a hepatocyte-targeted N-acetylgalactosamine conjugated oligonucleotide that functions as an antagonist for miR-122, an essential host factor in the replication of the hepatitis C virus (HCV).
价 格：￥电议型 号：T39347产 地：中国大陆
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T39101HAV 3C proteinase-IN-1；HAV 3C proteinase-IN-1HAV 3C proteinase-IN-1
HAV 3C proteinase-IN-1 is a inhibitor of Hepatitis A virus 3C proteinase .
价 格：￥电议型 号：T39101产 地：中国大陆
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T38644Docetaxal；DocetaxalPNU-101383|||10-Acetyl docetaxel；PNU-101383|||10-Acetyl docetaxel
Docetaxal, also known as 10-Acetyl docetaxel, is an analog of Docetaxel exhibiting potent anticancer properties. It acts as a microtubule disassembly inhibitor, effectively inhibiting mitosis.
价 格：￥电议型 号：T38644产 地：中国大陆
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T38101Bisucaberin；BisucaberinBisucaberin
Bisucaberin is a siderophore and bacterial metabolite that has been found inA. haloplanktisand has anticancer activity.1,2It inhibits the growth of L1210 and 1MC carcinoma cells (IC50s = 9.7 and 12.7 μM, respectively) and sensitizes fibrosarcoma 1023 cells to macrophage-mediated cytolysis.
价 格：￥电议型 号：T38101产 地：中国大陆
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T37220JNJ-10181457 (hydrochloride)；JNJ-10181457 (hydrochloride)JNJ-10181457 (hydrochloride)
JNJ-10181457 (hydrochloride) is a non-imidazole H3 receptor antagonist that is brain-penetrating and selective, increasing NE and acetylcholine concentrations within the rat frontal cortex. Can be used for neurological-related research.
价 格：￥电议型 号：T37220产 地：中国大陆
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T37113Z62954982；化合物 Z62954982ZINC08010136；ZINC08010136
Z62954982 (ZINC08010136) is a selective inhibitor of Rac1, which stunts the growth and branching of neurons.Z62954982 inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arterioles.
价 格：￥电议型 号：T37113产 地：中国大陆
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T371011-Hydroxyanthraquinone；1-羟基蒽醌1-Hydroxyanthraquinone
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
价 格：￥电议型 号：T37101产 地：中国大陆
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T36935PKUMDL-LC-101-D04；化合物PKUMDL-LC-101-D04GPX4-Activator-1d4|||PKUMDL-LC-101-D04；GPX4-Activator-1d4|||PK
PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free assay, and at a concentration of 61 μM in wild-type, but not Gpx4-/-, mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 μM) reduced cholesterol peroxide-induced MEF death.
价 格：￥电议型 号：T36935产 地：中国大陆
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T3678Entrectinib；恩曲替尼RXDX-101|||NMS-E628；RXDX-101|||恩曲替尼|||NMS-E628
Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectinib blocks proliferation of ALK-dependent cell lines, including those with C1156Y or L1196M resistance mutations, and inhibits ALK‐dependent signaling. It has been shown to inhibit the growth of a non-small cell lung Y cell line bearing an EML4-ALK rearrangement. In mice bearing va
价 格：￥电议型 号：T3678产 地：中国大陆
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T36646Trastuzumab deruxtecan；德曲妥珠单抗DS-8201a|||VRN-101099|||DS 8201|||T-DXd；DS-8201a|||VRN-101099|||DS 8201
Trastuzumab deruxtecan (T-DXd) is an antibody-activated molecule coupling (ADC) with anticancer and antitumour activity.Trastuzumab deruxtecan has been shown to have an ameliorative effect in HER2-positive breast and gastric cancers.
价 格：￥电议型 号：T36646产 地：中国大陆
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T36274VH 101 phenol-alkylC6-amine；VH 101 phenol-alkylC6-amineVH 101 phenol-alkylC6-amine；VH 101 phenol-alk
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC6 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
价 格：￥电议型 号：T36274产 地：中国大陆
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T36273VH 101 phenol-alkylC4-amine；VH 101 phenol-alkylC4-amineVH 101 phenol-alkylC4-amine；VH 101 phenol-alk
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
价 格：￥电议型 号：T36273产 地：中国大陆
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T36101PsychotridinePsychotridinePsychotridine
Psychotridine is an alkaloid that has been found inP. forsterianaand has diverse biological activities.1,2,3It inhibits ADP-, collagen-, or thrombin-induced aggregation of washed isolated human platelets with IC50values of 1.4, 1.4, and 3.9 μM, respectively.1Psychotridine (2.5 or 5 μM) is cytotoxic to HTC rat hepatocellular carcinoma cells.2It reduces paw licking induced by capsaicin in mice when administered at doses of 0.5, 2.5, or 5 mg/kg.3
价 格：￥电议型 号：T36101产 地：中国大陆
