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  • T63047SLP9101555；化合物SLP9101555SLP9101555

    SLP9101555 is a potent and selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 90 nM.SLP9101555 has a high affinity for SphK2, which is 200-fold higher than that of SphK1.SLP9101555 dramatically reduces extracellular S1P sphingosine 1-phosphate (S1P) levels.

    价 格：￥电议型 号：T63047产 地：中国大陆

  • T62101hCAXII-IN-2；化合物 hCAXII-IN-2hCAXII-IN-2

    hCAXII-IN-2 (compound 5i) is a potent inhibitor of human carbonic anhydrase XII (hCA XII) (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity against hCA I and hCA II.

    价 格：￥电议型 号：T62101产 地：中国大陆

  • T6194Fidaxomicin；非达米星Tiacumicin B|||OPT-80|||Clostomicin B1|||PAR-101；非达米星|||Tiacumicin B|||OPT-80|||Clos

    Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme elevations during therapy or to instances of clinically apparent, acute liver injury.

    价 格：￥电议型 号：T6194产 地：中国大陆

  • T61189E7016；化合物E7016GPI 21016；GPI 21016

    E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo.

    价 格：￥电议型 号：T61189产 地：中国大陆

  • T61101FLT3-IN-13；化合物 FLT3-IN-13FLT3-IN-13

    FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic cells. It exhibits potent activity against these targets, with IC50 values of 2.26 μM for both. Moreover, FLT3-IN-13 induces cell cycle arrest at the G2/M phase and promotes apoptosis. Notably, it displays considerable anticytotoxic activity, specifically against leukemia [1].

    价 格：￥电议型 号：T61101产 地：中国大陆

  • T61019FAK-IN-4；化合物 FAK-IN-4FAK-IN-4

    FAK-IN-4 (Compound 7d) has anticancer activities that can induce cell apoptosis. FAK-IN-4 is potential inhibitor of FAK [1].

    价 格：￥电议型 号：T61019产 地：中国大陆

  • T61018DPP-4-IN-2；化合物 DPP-4-IN-2DPP-4-IN-2

    DPP-4-IN-2 (compound b2) is a structural analog of Alogliptin that can be used for the research of diabetes. DPP-4-IN-2 is a potent dipeptidyl peptidase 4 (DPP-4) inhibitor with an IC50 value of 79 nM [1].

    价 格：￥电议型 号：T61018产 地：中国大陆

  • T61017Topoisomerase II inhibitor 6；化合物 Topoisomerase II inhibitor 6Topoisomerase II inhibitor 6

    Topoisomerase II inhibitor 6 (Compound 5) is a tryptanthrin derivative. Topoisomerase II inhibitor 6 is a potent and selective topoisomerase II inhibitor. Topoisomerase II inhibitor 6 blocks the CCRF-CEM cell cycle in the G2 phase and induces DNA double-strand breaks (DSB). Topoisomerase II inhibitor 6 exhibits antiproliferative activity on different tumor cell lines. Topoisomerase II inhibitor 6 has the potential for the research of cancer diseases [1].

    价 格：￥电议型 号：T61017产 地：中国大陆

  • T61016EMI1；化合物EMI1EMI1

    EMI1 is an inhibitor of EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI1 has research value in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC).

    价 格：￥电议型 号：T61016产 地：中国大陆

  • T61015hCAIX/XII-IN-2；化合物 hCAIX/XII-IN-2hCAIX/XII-IN-2

    hCAIX/XII-IN-2 (compound 6a) is a potent and selective inhibitor of hCAIX and hCAXII. The Ki values of hCAIX/XII-IN-2 for hCAI, hCAII, hCAIX and hCAXII are >10000, >10000, 30.0, 3.6 nM, respectively [1].

    价 格：￥电议型 号：T61015产 地：中国大陆

  • T61014Galectin-8-IN-1；化合物 Galectin-8-IN-1Galectin-8-IN-1

    Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N) with a Kd value of 48 μM. Galectin-8-IN-1 is 15-fold more selective than galectin-3 and even better than other mammalian galectins.

    价 格：￥电议型 号：T61014产 地：中国大陆

  • T61013Bromodiphenhydramine；化合物 BromodiphenhydramineBromodiphenhydramine

    Bromodiphenhydramine (Ambodryl) has antimicrobial activities which can be used in the cutaneous allergies research. Bromodiphenhydramine is an effective antihistamine that can inhibit a large number of Gram-negative and Gram-positive bacteria [1] [2] [3].

    价 格：￥电议型 号：T61013产 地：中国大陆

  • T61012Bobcat339 hydrochloride；化合物 Bobcat339 hydrochlorideBobcat339 hydrochloride

    Bobcat339 hydrochloride can be used in the field of epigenetics and as a starting point for new therapeutics targeting DNA methylation and gene transcription. Bobcat339 hydrochloride is a potent and selective cytosine-based TET enzyme inhibitor with the IC50 values of 33 μM and 73 μM for TET1 and TET2, respectively [1].

    价 格：￥电议型 号：T61012产 地：中国大陆

  • T61011Izuforant；化合物 IzuforantIzuforant

    Izuforant (JW1601) (Compound 24) has potent anti-inflammatory and anti-pruritic activities. Izuforant has a binding affinity for human serotonin 3 receptor (h5-HT3R) with an IC50 value of 9.1 μM. Izuforant is also an orally active antagonist of histamine H4 receptor (H4R) with an IC50 value of 36 nM against human H4R [1] [2].

    价 格：￥电议型 号：T61011产 地：中国大陆

  • T61010Bromfenac；化合物 BromfenacBromfenac

    Bromfenac can be used in the research of ocular inflammation that is a potent and orally active COX inhibitor with IC50 values of 5.56 and 7.45 nM for COX-1 and COX-2, respectively [1].

    价 格：￥电议型 号：T61010产 地：中国大陆

  • T6101Entospletinib；化合物EntospletinibGS-9973；GS-9973

    Entospletinib (GS-9973) (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable.

    价 格：￥电议型 号：T6101产 地：中国大陆

  • T60618ZC0101；化合物 ZC0101ZC0101

    ZC0101 is a potent, orally active dual inhibitor of IDO1 and TrxR with IC 50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 potently induces apoptosis and ROS accumulation in cancer cells [1].

    价 格：￥电议型 号：T60618产 地：中国大陆

  • T60101PLN-1474；化合物PLN-1474PLN1474；PLN1474

    PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.

    价 格：￥电议型 号：T60101产 地：中国大陆

  • T5995Larotrectinib；化合物LarotrectinibLOXO-101|||ARRY-470；LOXO-101|||ARRY-470

    Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM).

    价 格：￥电议型 号：T5995产 地：中国大陆

  • T5449Bamaquimast；巴马司特L 0042|||F 10126；L 0042|||F 10126

    Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases.

    价 格：￥电议型 号：T5449产 地：中国大陆

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