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T39266hTrkA-IN-1;hTrkA-IN-1hTrkA-IN-1
hTrkA-IN-1 is a potent and orally active inhibitor of TrkA kinase with an IC 50 of 1.3 nM, compound 2.hTrkA-IN-1 can be used for the study of inflammatory disease, such as prostatitis, pelvic, et al.
价 格:¥电议型 号:T39266产 地:中国大陆
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T39217PKA-IN-1;PKA抑制剂4PKA-IN-1
PKA-IN-1 is a selective and potent cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor (IC50: 0.03 μM).PKA-IN-1 can be used to study diseases of the immune system.
价 格:¥电议型 号:T39217产 地:中国大陆
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T39183Okadaic acid ammonium salt;冈田酸铵盐Okadaic acid ammonium salt
Okadaic acid ammonium salt, a marine toxin, serves as an inhibitor of protein phosphatases (PP), displaying a higher affinity for PP2A (IC 50 =0.1-0.3 nM) alongside inhibitory effects on PP1 (IC 50 =15-50 nM), PP3 (IC 50 =3.7-4 nM), PP4 (IC 50 =0.1 nM), and PP5 (IC 50 =3.5 nM), but does not affect PP2C. By inhibiting PPs, this compound promotes protein phosphorylation and acts as a tumor promoter. Additionally, it is involved in inducing tau phosphorylation.
价 格:¥电议型 号:T39183产 地:中国大陆
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T39121OdatroltideOdatroltideDHDMIQK(KAP)|||Odatroltide
Odatroltide is a nanoscale P-selectin inhibitor that serves as a nano-delivery system for 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to specifically target the thrombus.
价 格:¥电议型 号:T39121产 地:中国大陆
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T39093TCTDSTNCYKAT;TCTDSTNCYKATTCTDSTNCYKAT
TCTDSTNCYKAT is an engineered-variant peptide of antifreeze protein (AFP).
价 格:¥电议型 号:T39093产 地:中国大陆
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T3801(Rac)-Byakangelicin;白当归素Bjacangelicin|||Bjakangelicin|||Biacangelicin|||7H-Furo[3,2-g][1]benzopyran-
(Rac)-Byakangelicin (7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-) is an antineoplastic agent.
价 格:¥电议型 号:T3801产 地:中国大陆
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T37808Kaliotoxin;KaliotoxinKaliotoxin
Kaliotoxin is an inhibitor of neuronal BK-type peptide groups and specifically inhibits Kv channels and calcium-activated potassium channels. Kaliotoxin has research significance on the regulation of cell membrane potential and neuronal excitability. The product number is T37808 and the CAS number is 145199-73-1
价 格:¥电议型 号:T37808产 地:中国大陆
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T37557(-)-(α)-Kainic Acid (hydrate);(-)-(α)-Kainic Acid (hydrate)(-)-(α)-Kainic Acid (hydrate)
(-)-(α)-Kainic Acid (hydrate) is a potent excitotoxic agent that can induce seizures. (-)-(α)-Kainic Acid (hydrate) is also an agonist of ionotropic glutamate receptor subtypes.
价 格:¥电议型 号:T37557产 地:中国大陆
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T37386Dihydro Montelukast;Dihydro MontelukastDihydro Montelukast
Dihydro montelukast is a potential impurity found in commercial montelukast preparations. Montelukast (sodium salt) is a potent and selective cysteinyl leukotriene 1 (CysLT1) receptor antagonist. Formulations containing montelukast are used for the treatment of asthma as well as for the symptoms associated with allergic rhinitis.
价 格:¥电议型 号:T37386产 地:中国大陆
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T37016Iralukast (CGP 45715A);Iralukast (CGP 45715A)Iralukast (CGP 45715A)
Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.
价 格:¥电议型 号:T37016产 地:中国大陆
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T36819Ac-FLTD-CMK;化合物Ac-FLTD-CMKAc-FLTD-CMK
Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7 nM, 1.49 μM and 329 nM, respectively. Ac-FLTD-CMK showed potency against caspases-1, caspases-4 and caspases-11, but not against apoptosis-associated caspase-3.
价 格:¥电议型 号:T36819产 地:中国大陆
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T3667Kalii Dehydrographolidi Succinas;穿琥宁Ddhads|||Dehydroandrographolide Succinate Potasium Salt;Ddhads||
Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity.
价 格:¥电议型 号:T3667产 地:中国大陆
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T3665Tectoridin;射干苷Shekanin;射干苷|||Shekanin
Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin and its five metabolites inhibits the activities of lens aldose reductase in rat (IC : 1.4-15.5 μM).
价 格:¥电议型 号:T3665产 地:中国大陆
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T3638Leukadherin-1;化合物Leukadherin-1Leukadherin-1
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation.
价 格:¥电议型 号:T3638产 地:中国大陆
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T36365KAPA (hydrochloride)KAPA (hydrochloride)KAPA (hydrochloride)|||7-keto-8-Aminopelargomic Acid
Biotin is a growth factor that plays an important role in numerous reactions that are critical to microorganisms, plants, and animals. Biotin has a strong affinity for the protein avidin, a trait that has been utilized for many assay reporter applications. KAPA is a key intermediate in the biotin biosynthetic pathway.[1]
价 格:¥电议型 号:T36365产 地:中国大陆
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T36019PKA Inhibitor (5-24) (trifluoroacetate salt);PKA Inhibitor (5-24) (trifluoroacetate salt)PKA Inhibit
PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki= 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein.1It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite.1The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr235and Phe239form a sandwich-like structure with residue Phe10of PKI (5-24).2
价 格:¥电议型 号:T36019产 地:中国大陆
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T35951Alkaline Phosphatase;碱性磷酸酶Alkaline Phosphatase
Alkaline Phosphatase is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values.
价 格:¥电议型 号:T35951产 地:中国大陆
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T35558KAAD-CyclopamineCyclopamine-KAADKAAD Cyclopamine|||KAADCyclopamine
Cyclopamine-KAAD is a potent inhibitor of hedgehog signaling with an IC50 value of 20 nM in a Shh-LIGHT2 assay. It blocks binding of BODIPY-cyclopamine to cells expressing Smoothened (Smo) in a dose-dependent manner. Cyclopamine-KAAD is cell-permeable and binds to SmoA1 to promote its exit from the endoplasmic reticulum. It inhibits the invasion and migration (45.9 and 43.3% inhibition, respectively) of Bel-7402 hepatocarcinoma cells and decreases the expression of nuclear glioma-associated onco
价 格:¥电议型 号:T35558产 地:中国大陆
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T35327Carrageenan;Carrageenankappa-Carrageenan;kappa-Carrageenan
Carrageenan (kappa-Carrageenan) 是一种从食用红海藻中提取的天然碳水化合物(多糖)。Carrageenan 具有抗凝活性、抗血栓形成活性、抗病毒活性、抗肿瘤活性和免疫调节活性。
价 格:¥电议型 号:T35327产 地:中国大陆
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T352365α-Hydroxy-6-keto cholesterol;5α-羟基-6-酮胆固醇YS 64|||Yakkasterone;YS 64|||Yakkasterone|||5α-羟基-6-酮胆固醇
Yakkasterone is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone.
价 格:¥电议型 号:T35236产 地:中国大陆