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T61923ERRα antagonist-2；化合物 ERRα antagonist-2ERRα antagonist-2
ERRα antagonist-2 (Compound 11) is a potential Reverse agonist of ERR α (estrogen receptor related receptor α) (IC50=0.80 μ M). ERRα antagonist-2 can inhibit the migration and invasion of ER-negative MDA-MB-231 cells. ERRα antiagonist-2 inhibits the growth of breast cancer in vivo.
价 格：￥电议型 号：T61923产 地：中国大陆
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T6185Gambogic Acid；藤黄酸Beta-Guttiferrin|||Guttatic Acid|||Guttic Acid；藤黄酸|||Beta-Guttiferrin|||藤黄酸 A|||Gut
Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1. The IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 uM, respectively.
价 格：￥电议型 号：T6185产 地：中国大陆
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T61689ThrRS-IN-1；化合物 ThrRS-IN-1ThrRS-IN-1
ThrRS-IN-1 (Compound 30d) is a potent inhibitor of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica (Se ThrRS), exhibiting an IC50 of 1.4 μM and a Kd of 1.36 μM. It uniquely targets both the tRNA Thr and L-threonine binding sites of ThrRS, demonstrating significant antibacterial activities [1].
价 格：￥电议型 号：T61689产 地：中国大陆
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T6083AZD8330；化合物AZD8330ARRY-424704|||ARRY-704；ARRY-424704|||ARRY-704
AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
价 格：￥电议型 号：T6083产 地：中国大陆
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T60772ERRγ agonist-1；化合物 ERRγ agonist-1ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research. ERRγ agonist-1 increases the ERRγ transcriptional activities that is a potent agonist of ERRγ [1].
价 格：￥电议型 号：T60772产 地：中国大陆
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T60653CFTR corrector 9；化合物CFTR corrector 9CFTR corrector 9
CFTR Corrector 9, a cystic fibrosis transmembrane conductance regulator (CFTR) modulator, is employed in the research of cystic fibrosis (CF) and related CFTR-associated disorders [1].
价 格：￥电议型 号：T60653产 地：中国大陆
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T60554Schnurri-3 inhibitor-1；化合物Schnurri-3抑制剂-1Schnurri-3 inhibitor-1
Schnurri-3 inhibitor-1 is a potent inhibitor of schnurri-3, an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in Shn3FFL (osteoblast cell line, AC50= 2.09 μM). Schnurri-3 inhibitor-1 has research value in osteoporosis.
价 格：￥电议型 号：T60554产 地：中国大陆
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T60475RRD-251；化合物 RRD-251RRD-251
RRD-251 is an Rb-Raf-1 interaction inhibitor that induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine[1].
价 格：￥电议型 号：T60475产 地：中国大陆
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T60443Nurr1 agonist 1；化合物 Nurr1 agonist 1Nurr1 agonist 1
Nurr1 agonist 1 is an inverse agonist tool for the neuroprotective transcription factor Nurr1 which is an appealing target to treat neurodegenerative diseases.
价 格：￥电议型 号：T60443产 地：中国大陆
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T602241H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-；化合物T602241H-Pyrr
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modulator with EC2 (Concentration that doubles the intensity of the AMPA-induced current) of 35 μM.
价 格：￥电议型 号：T60224产 地：中国大陆
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T60098MSC2504877；化合物MSC25048773-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one；3
MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phospho-Rb.
价 格：￥电议型 号：T60098产 地：中国大陆
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T60086TTBK1-IN-2；化合物TTBK1-IN-2N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine；N-[4-(4-chl
TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 ?M. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.
价 格：￥电议型 号：T60086产 地：中国大陆
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T5S1607Morusin；桑辛素Mulberrochromene；Mulberrochromene|||桑辛素
1. Morusin (Mulberrochromene) possesses antitumor effects of cell lines including HT-29, A549, MCF-7, and MDA-MB-231, through suppressing STAT3 and NFκB attenuation mediated apoptosis induction. 2. Morusin possesses anti-oxidant and anti-inflammatory effects.
价 格：￥电议型 号：T5S1607产 地：中国大陆
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T5S1598Mulberroside C桑皮苷 C桑皮苷 C|||桑皮苷C
1. Mulberroside C has antioxidant activity.
价 格：￥电议型 号：T5S1598产 地：中国大陆
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T5S1025Picfeltarraenin IA苦玄参苷 IA苦玄参苷IA|||Picfeltarraenin A|||苦玄参苷 IA
1. Picfeltarraenin IA (Picfeltarraenin A), IB, IV, X, XI are stronger AChE inhibitions than the known AChE inhibitor Tacrine.
价 格：￥电议型 号：T5S1025产 地：中国大陆
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T5995Larotrectinib；化合物LarotrectinibLOXO-101|||ARRY-470；LOXO-101|||ARRY-470
Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM).
价 格：￥电议型 号：T5995产 地：中国大陆
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T59362,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE；化合物 T59362,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE|||2,3 DIHYDRO 1
2,3-DIHYDRO-1H-PYRROLO[2,3-B]PYRIDINE has a wide range of applications in life science related research.
价 格：￥电议型 号：T5936产 地：中国大陆
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T5851N-Methylpyrrolidone；N-甲基吡咯烷酮1-Methyl-2-pyrrolidinone；N-甲基吡咯烷酮|||1-Methyl-2-pyrrolidinone
N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone) (1-Methyl-2-pyrrolidinone) is a five-membered cyclic amide. N-Methylpyrrolidone is a widely used industrial organic polar solvent in the manufacture of adhesives, paints, fuels, and pharmaceuticals.
价 格：￥电议型 号：T5851产 地：中国大陆
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T5835PROTAC ERRα ligand 2；化合物PROTAC ERRα ligand 2PROTAC ERRα ligand 2
PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist( IC50 : 5.67 nM)
价 格：￥电议型 号：T5835产 地：中国大陆
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T5802Stearyl glycyrrhetinate；硬脂醇甘草亭酸酯Stearyl glycyrrhetinate
Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.
价 格：￥电议型 号：T5802产 地：中国大陆
