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  • T40561ThrRS-IN-2；ThrRS-IN-2ThrRS-IN-2

    ThrRS-IN-2 is an inhibitor of threonyl-tRNA synthetase (ThrRS), exhibiting an inhibition concentration (IC50) value of 56.5 ± 3.5 μM.

    价 格：￥电议型 号：T40561产 地：中国大陆

  • T40078(R)-Pomalidomide-pyrrolidine；(R)-Pomalidomide-pyrrolidine(R)-Pomalidomide-pyrrolidine

    (R)-Pomalidomide-pyrrolidine, a CRBN ligand, can be conjugated to a protein-targeting ligand via a linker, resulting in the formation of PROTACs.

    价 格：￥电议型 号：T40078产 地：中国大陆

  • T39837PROTAC ERRα Degrader-3；PROTAC ERRα Degrader-3PROTAC ERRα Degrader-3

    PROTAC ERRα Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades the ERRα protein. At a concentration of 30 nM, this compound exhibits a remarkable degradation capability, reducing the ERRα protein levels by >80%. Importantly, PROTAC ERRα Degrader-3 shows no activity against the ERRβ and ERRγ proteins.

    价 格：￥电议型 号：T39837产 地：中国大陆

  • T3975AZD9496；化合物AZD9496AZD9496|||AZD 9496|||AZD 9496|||AZD-9496|||AZD-9496|||Estrogen Receptor/ERR|||inhi

    AZD9496 is an orally available selective estrogen receptor(ERα) antagonist, with potential antineoplastic activity.

    价 格：￥电议型 号：T3975产 地：中国大陆

  • T3933Jatrorrhizine；药根碱Yatrorizine|||neprotin；Yatrorizine|||neprotin|||药根碱

    Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits monoamine oxidase (IC50 4 micromolar for MAO-A and 62 for MAO-B).

    价 格：￥电议型 号：T3933产 地：中国大陆

  • T3888Scopolin东莨菪苷Murrayin|||东莨菪甙|||Scopoloside|||东莨菪苷

    Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for angiogenesis related diseases and can serve as a structural base for screening more potent synthetic analogs.

    价 格：￥电议型 号：T3888产 地：中国大陆

  • T3868Agnuside；穗花牡荆苷chasteberry oil；牡荆油|||穗花牡荆苷|||chasteberry oil

    Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at concentrations of 5, 25, and 100 μM, respectively.

    价 格：￥电议型 号：T3868产 地：中国大陆

  • T38499κ-Carrageenan；κ-Carrageenanκ-Carrageenan

    κ-Carrageenan, a natural polymer found predominantly in red seaweeds, can serve as an effective drug carrier for delivering curcumin to cancer cells and inducing apoptosis. Additionally, κ-Carrageenan holds promise as a potential inflammatory agent, amplifying existing intestinal inflammation.

    价 格：￥电议型 号：T38499产 地：中国大陆

  • T38395Pyrrole-2-carboxaldehyde；2-吡咯甲醛Pyrrole-2-carboxaldehyde

    Pyrrole-2-carboxaldehyde exhibits distinctive vibrational and electronic properties which serve to validate its dimeric state in the solid phase and monomeric state in the solution phase.

    价 格：￥电议型 号：T38395产 地：中国大陆

  • T38275Kirromycin；KirromycinKirromycin

    Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits elongation factor Tu-dependent peptidyl transfer activity in E. coli.

    价 格：￥电议型 号：T38275产 地：中国大陆

  • T38247Lactoferricin B (4-14), bovine TFA；Lactoferricin B (4-14), bovine TFALactoferricin B (4-14), bovine

    Lactoferricin B (4-14), bovine (TFA), is a peptide derived from bovine lactoferrin, specifically consisting of residues 4-14. This compound exhibits broad-spectrum antimicrobial activity against various microorganisms[1].

    价 格：￥电议型 号：T38247产 地：中国大陆

  • T38166Ferrioxamine E；Ferrioxamine EFerrioxamine E

    Ferrioxamine E is a bacterial siderophore produced by a variety of bacteria including S. glaucescens, M. luteus, and P. mendocina. Ferrioxamines, including ferrioxamine E, are the sole iron source for Salmonella, and have been used as growth enriching agents in the detection of Salmonella in food and industrial applications.

    价 格：￥电议型 号：T38166产 地：中国大陆

  • T38014Heronapyrrole B；Heronapyrrole BHeronapyrrole B

    Heronapyrrole B is a farnesylated 2-nitropyrrole bacterial metabolite that has been found inStreptomycesand has antibacterial activity.1,2It is active against the Gram-positive bacteriaS. aureusandB. subtilis(MICs = 1.8 and 7.5 μM, respectively) but not Gram-negativeP. aeruginosaorE. coli.1

    价 格：￥电议型 号：T38014产 地：中国大陆

  • T37788Resorufin benzyl ether；Resorufin benzyl etherResorufin benzyl ether

    Resorufin benzyl ether is a fluorometric probe that acts as a substrate for cytochrome P450 (CYP)3A4. It is typically used near its apparent Km value of 30 μM to screen the inhibition/activation potential of test compounds, to predict potential drug-drug interactions, or to monitor other CYP450 activities. Upon enzyme cleavage, resorufin benzyl ether generates a red fluorescent product (ex. 571 nm/em. 585 nm).

    价 格：￥电议型 号：T37788产 地：中国大陆

  • T37686CFTR corrector 6；CFTR corrector 6CFTR corrector 6

    CFTR corrector 6 is a highly effective CFTR potentiator utilized in research on cystic fibrosis (CF) and related CFTR-associated disorders[1]. This potent compound exhibits potentiation activity on the Cystic Fibrosis Transmembrane conductance Regulator (CFTR), rendering it beneficial for investigations in CF and other associated conditions.

    价 格：￥电议型 号：T37686产 地：中国大陆

  • T37426FIIN-1；化合物FIIN-1FGFR irreversible inhibitor-1；FGFR irreversible inhibitor-1

    FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3, FGFR4, Flt1, Flt14, respectively.FIIN-1 inhibited FGFR1, FGFR2, FGFR3, FGFR4, with IC50 of 9.2, 6.2, 11.9 and 189 nM. FIIN-1 inhibited FGFR1, FGFR2, FGFR3 and FGFR4, with IC50s of 9.2, 6.2, 11.9 and 189 nM, respectively.

    价 格：￥电议型 号：T37426产 地：中国大陆

  • T37331PyrrophenonePyrrophenonePyrrophenone

    The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2α with an IC50 of 4.2 nM in enzyme assays and potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively). Its action is reversible and selective, as py

    价 格：￥电议型 号：T37331产 地：中国大陆

  • T37290Resolvin D3 methyl ester；Resolvin D3 methyl esterResolvin D3 methyl ester

    Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.

    价 格：￥电议型 号：T37290产 地：中国大陆

  • T37169Resolvin D2 methyl ester；Resolvin D2 methyl esterResolvin D2 methyl ester

    Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation. RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.

    价 格：￥电议型 号：T37169产 地：中国大陆

  • T37168Resolvin D1 methyl ester；Resolvin D1 methyl esterResolvin D1 methyl ester；Resolvin D1 methyl ester

    Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM. RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracell

    价 格：￥电议型 号：T37168产 地：中国大陆

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