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T7397GSK547Inhibitor,RIP kinase,inhibit,GSK-547,GSK547,Receptor-interacting protein kinases,RIPK,GSK 547
GSK547 is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.
价 格:¥电议型 号:T7397产 地:中国大陆
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TP1604LThioredoxin reductase peptide acetateThioredoxin reductase peptide acetate
Thioredoxin reductase peptide acetate corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfide bond of thioredoxin (Trx) and is similar in structure and mechanism to glutathione reductase except for a C-terminal 16-amino acid extension containing a rare vicinal selenylsulfide bond.
价 格:¥电议型 号:TP1604L产 地:中国大陆
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T4444A-674563 HCl (552325-73-2(free base))A 674563 HCl (552325 73 2(free base)),A674563 HCl (552325732(fr
A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for Akt1 versus additional kinases in the CMGC, CAMK, and TK families [1].
价 格:¥电议型 号:T4444产 地:中国大陆
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T8506THPP-1PDE10A,SIMA,object,THPP 1,recognition,Phosphodiesterase (PDE),Inhibitor,inhibit,novel,THPP-1,T
THPP-1 is a potent and orally bioavailable inhibitor of PDE10A(Ki of 1 nM and 1.3 nM for human and rat PDE10A, respectively).
价 格:¥电议型 号:T8506产 地:中国大陆
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T6843GDC-0623Mitogen-activated protein kinase kinase,Apoptosis,inhibit,MEK,Inhibitor,MAP2K,MAPKK,MEK inhi
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
价 格:¥电议型 号:T6843产 地:中国大陆
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T11184EML4-ALK kinase inhibitor 1
EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
价 格:¥电议型 号:T11184产 地:中国大陆
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T9714Atpenin A5preconditioning,sensitive,mKATP,Atpenin A 5,Atpenin A5,ischemia,potassium,complex II,Inhib
Atpenin A5 is a potent and highly specific?complex II?inhibitor (IC50?~10 nM). Atpenin A5 is also an effective?mKATP?channel?agonist and cardioprotective agent[1].
价 格:¥电议型 号:T9714产 地:中国大陆
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T7128TH-257LIM Kinase (LIMK),LIMKs,Inhibitor,TH-257,inhibit,TH257
TH 257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).
价 格:¥电议型 号:T7128产 地:中国大陆
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T9078LY3405105anticancer,Cyclin dependent kinase,CDK,MCF7,SNU-16,Cyclin-dependent kinase,LY 3405105,LY340
LY3405105 is a novel CDK7 inhibitors.
价 格:¥电议型 号:T9078产 地:中国大陆
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T5372L-SelenoMethionineselenium,peroxidase,glutathione,dietary,L-SelenoMethionine,Apoptosis,cancer,L Sele
L-Selenomethionine is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
价 格:¥电议型 号:T5372产 地:中国大陆
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T8703yGsy2p-IN-1diseases,synthase,hGYS1,pyrazole,GSDs,yGsy2p,yGsy2pIN1,yGsy-2p-IN-1,glycogen,storage,yGsy
yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs)
价 格:¥电议型 号:T8703产 地:中国大陆
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TP1696LCGGRGD acetate(1260223-44-6 free base)CGGRGD acetate(1260223446 free base),CGGRGD acetate(1260223 44
CGGRGD acetate is a RGD derivative with cysteine as the n-terminal. CGGRGD was synthesized by solid phase peptide synthesis technology, and amino2-cyanobenzothiazole (2-cyanobenzothiazole) (2-cyanobenzothiazole (CBT) was added on the surface of PCL fiber for ammoniation.
价 格:¥电议型 号:TP1696L产 地:中国大陆
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TN3866Dihydrosinapyl alcoholDihydrosinapyl alcohol,Inhibitor,lignocellulose,inhibit
Dihydrosinapyl alcohol is a natural product from Clerodendranthus spicatus.
价 格:¥电议型 号:TN3866产 地:中国大陆
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T6816DASA-58DASA58,inhibit,Inhibitor,DASA 58,DASA-58,glycolysis,TXNIP,cancer metabolism,Pyruvate Kinase,p
DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.
价 格:¥电议型 号:T6816产 地:中国大陆
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T8508HDAC-IN-3Histone deacetylases,Inhibitor,inhibit,HDAC,HDACIN3,HDAC IN 3
HDAC-IN-3 is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.
价 格:¥电议型 号:T8508产 地:中国大陆
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T7752(S,R,S)-AHPC-MeVHL ligand-2,VHL ligand2,Inhibitor,inhibit,Ligands for E3 Ligase,(S,R,S) AHPC Me,(S,R
(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
价 格:¥电议型 号:T7752产 地:中国大陆
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T8832Eledoisin trifluoroacetate (69-25-0 free base)Eledoisin trifluoroacetate (69250 free base),Eledoisin
Eledoisin is a peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE P; it is a potent vasodilator and increases capillary permeability.
价 格:¥电议型 号:T8832产 地:中国大陆
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T13253UmibecestatBACE,Beta-secretase,inhibit,CNP-520,β-Secretase,CNP 520,Inhibitor
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer´s disease.
价 格:¥电议型 号:T13253产 地:中国大陆
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T9217USP7-IN-8inhibit,USP7,Inhibitor,USP-7-IN-8,Deubiquitinase,DUBs,USP7IN8,anticancer,USP7 IN 8
Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. USP7-IN-8 has anticancer effects.
价 格:¥电议型 号:T9217产 地:中国大陆
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T9758dCeMM3?degradation,dCeMM 3,dCeMM3?,Inhibitor,inhibit,CDK,CDK12,Cyclin dependent kinase,glue degrader
dCeMM3 is a glue degrader. dCeMM3 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, result in inducing ubiquitination and degradation of cyclin K.
价 格:¥电议型 号:T9758产 地:中国大陆