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  • T15645Pamicogrel;帕米格雷KBT3022;KBT3022|||帕米格雷

    Pamicogrel (KBT3022) is an inhibitor of COX.

    价 格:¥电议型 号:T15645产 地:中国大陆

  • T15644KAT681;化合物 T15644T0681;T0681

    KAT681 is a liver selective thyromimetic.

    价 格:¥电议型 号:T15644产 地:中国大陆

  • T15643Kainic acid红藻氨酸红藻氨酸

    In the CNS, Kainic acid is an effective agonist at excitatory amino acid receptor subtypes.

    价 格:¥电议型 号:T15643产 地:中国大陆

  • T15642KAG-308;化合物 T15642KAG-308

    KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP2, EP3, and IP receptor. KAG-308 suppresses colitis and promotes histological mucosal healing, which potently inhibits TNF-α production.

    价 格:¥电议型 号:T15642产 地:中国大陆

  • T15641K777;化合物K777APC-3316;APC-3316

    K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, which is the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 targets cathepsin-mediated cell entry and wxibits a broad-spectrum antiviral activity. K777 inhibits EBOV and SARS-CoV pseudovirus entry with IC50 values of 0.87

    价 格:¥电议型 号:T15641产 地:中国大陆

  • T15640K134;化合物 T15640OPC33509;OPC33509

    K134 is an inhibitor of phosphodiesterase 3. The IC50s of K134 for PDE3A, PDE3B, PDE5, PDE2 and PDE4 are 0.1, 0.28, 12.1, >300 and >300 μM, respectively.

    价 格:¥电议型 号:T15640产 地:中国大陆

  • T1564Cisplatin顺铂cis-Diaminodichloroplatinum|||CDDP|||顺铂

    Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy.

    价 格:¥电议型 号:T1564产 地:中国大陆

  • T15639K-756;化合物K-756K-756

    K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 (IC50 = 31 nM) and TNKS2 (IC50 = 36 nM).

    价 格:¥电议型 号:T15639产 地:中国大陆

  • T15638K-252c;化合物 T15638K-252c

    K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 μM). K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells.

    价 格:¥电议型 号:T15638产 地:中国大陆

  • T15637K-252b;化合物 T15637K-252b

    K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor. It is effective in inhibiting extracellular kinases in cultured cells due to its inability to freely cross the cell membrane.

    价 格:¥电议型 号:T15637产 地:中国大陆

  • T15636K-252a;化合物 T15636Antibiotic K 252a|||Antibiotic SF 2370|||SF2370;Antibiotic K 252a|||Antibiotic SF 2

    K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively).

    价 格:¥电议型 号:T15636产 地:中国大陆

  • T15635JZP-430;化合物JZP-430JZP-430

    JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).

    价 格:¥电议型 号:T15635产 地:中国大陆

  • T15634JYL 1421化合物JYL 1421SC 0030

    JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).

    价 格:¥电议型 号:T15634产 地:中国大陆

  • T15633JW74;化合物JW74JW74

    JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).

    价 格:¥电议型 号:T15633产 地:中国大陆

  • T15632JW 642;化合物JW 642JW 642

    JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).

    价 格:¥电议型 号:T15632产 地:中国大陆

  • T15631JTK-853;化合物 T15631JTK-853

    JTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase. It also displays effective antiviral activity in HCV replicon cells (EC50s: 0.38 and 0.035 μM in genotype 1a H77 and 1b Con1 strains, respectively).

    价 格:¥电议型 号:T15631产 地:中国大陆

  • T15630Tilmacoxib;替马考昔RWJ57504|||JTP19605|||JTE522;RWJ57504|||JTP19605|||替马考昔|||JTE522

    Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).

    价 格:¥电议型 号:T15630产 地:中国大陆

  • T1563Nifuroxazide;硝呋齐特Diarlidan|||Nifuroxazid|||Dicoferin;Diarlidan|||硝呋齐特|||Nifuroxazid|||Dicoferin|||硝呋

    Nifuroxazide (Diarlidan) is an orally available and cell-permeable nitrofuran-based antidiarrheal agent. It has the inhibitory effect against the activation of cellular STAT1/3/5 transcription.

    价 格:¥电议型 号:T1563产 地:中国大陆

  • T15629JTE-013;化合物JTE-013JTE-013

    JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).

    价 格:¥电议型 号:T15629产 地:中国大陆

  • T15628JT010;化合物JT010JT010

    JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).

    价 格:¥电议型 号:T15628产 地:中国大陆

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