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  • T15627(S)-JQ-35化合物 T15627TEN-010

    (S)-JQ-35 (TEN-010) is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins. It has a potential antineoplastic activity.

    价 格：￥电议型 号：T15627产 地：中国大陆

  • T15626JPM-OEt；化合物 T15626JPM-OEt

    JPM-OEt is a broad spectrum cysteine cathepsin inhibitor with antitumor activity. JPM-OEt binds covalently in the active site and irreversibly inhibits the cysteine cathepsin family.

    价 格：￥电议型 号：T15626产 地：中国大陆

  • T15625JNJ4796；化合物 T15625JNJ4796

    JNJ4796 is an oral active fusion inhibitor of the influenza virus, by inhibiting hemagglutinin (HA)-mediated fusion to neutralizing the influenza A group 1 virus. JNJ4796 mimics the functionality of the broadly neutralizing antibodies (bnAbs).

    价 格：￥电议型 号：T15625产 地：中国大陆

  • T15624JNJ-64619178；化合物JNJ-64619178JNJ-64619178

    JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.

    价 格：￥电议型 号：T15624产 地：中国大陆

  • T15623JNJ-61432059；化合物JNJ-61432059JNJ-61432059

    JNJ-61432059 is an oral active and selective negative modulator of TARP γ?8 Selective AMPAR(pIC50: 9.7).

    价 格：￥电议型 号：T15623产 地：中国大陆

  • T15622JNJ-54175446；化合物 JNJ-54175446JNJ-5446；JNJ-5446

    JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.

    价 格：￥电议型 号：T15622产 地：中国大陆

  • T15621Rilematovir；化合物RilematovirJNJ-53718678|||JNJ-678；JNJ-53718678|||JNJ-678

    Rilematovir (JNJ-678) is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus treatment.

    价 格：￥电议型 号：T15621产 地：中国大陆

  • T1562Rebamipide；瑞巴派特Proamipide|||OPC12759；Proamipide|||OPC12759|||瑞巴派特

    Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulate

    价 格：￥电议型 号：T1562产 地：中国大陆

  • T15619JNJ-46778212；化合物 JNJ-46778212VU 0409551；VU 0409551

    JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.

    价 格：￥电议型 号：T15619产 地：中国大陆

  • T15618JNJ-46281222；化合物 T15618JNJ-46281222

    JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator). It has nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50 = 7.71).

    价 格：￥电议型 号：T15618产 地：中国大陆

  • T15617JNJ-38877618；化合物JNJ-38877618OMO-1；OMO-1

    JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and 3 nM for wild type and mutant Met, respectively).

    价 格：￥电议型 号：T15617产 地：中国大陆

  • T15616JNJ-10198409；化合物JNJ-?10198409JNJ-?10198409；3-氟-N-(6,7-二甲氧基-2,4-二氢茚并[1,2-C〕吡唑-3-基苯基胺|||JNJ-?10198409

    JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.

    价 格：￥电议型 号：T15616产 地：中国大陆

  • T15615JND3229；化合物JND3229JND3229

    JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.

    价 格：￥电议型 号：T15615产 地：中国大陆

  • T15614JJKK 048；化合物JJKK 048JJKK 048

    JJKK 048 is a potent and selective MAGL inhibitor.

    价 格：￥电议型 号：T15614产 地：中国大陆

  • T15613JHU-083；化合物 T15613JHU-083

    JHU-083 is a selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells. JHU-083 also experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals.

    价 格：￥电议型 号：T15613产 地：中国大陆

  • T15612JH-VIII-157-02；化合物JH-VIII-157-02JH-VIII-157-02

    JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.

    价 格：￥电议型 号：T15612产 地：中国大陆

  • T15611JH-RE-06；化合物JH-RE-06JH-RE-06

    JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 also improves chemotherapy.

    价 格：￥电议型 号：T15611产 地：中国大陆

  • T15610JFD00244化合物 T15610JFD 00244|||JFD-00244|||JFD00244

    JFD00244 is an inhibitor of sirtuin 2 (SIRT2). It has an anti-tumor effect.

    价 格：￥电议型 号：T15610产 地：中国大陆

  • T1561Clobetasol propionate；丙酸氯倍他索Dermovate|||Clobetasol 17-propionate|||CGP9555|||Temovate|||CCl 4725；Der

    Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Clobetasol Propionate is the propionate salt form of clobetasol, a topical synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Specifically, clo

    价 格：￥电议型 号：T1561产 地：中国大陆

  • T15609JC-1；化合物JC-1CBIC2；CBIC2

    JC-1 (CBIC2) is a fluorescent lipophilic carbocyanine dye. It has been used to measure mitochondrial membrane potential. JC 1 can be used in a probe for measuring mitochondrial membrane potential by flow cytometry.

    价 格：￥电议型 号：T15609产 地：中国大陆

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