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T15513Hydroxy-PEG1-CH2-Boc;化合物 T15513Hydroxy-PEG1-CH2-Boc
Hydroxy-PEG1-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15513产 地:中国大陆
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T15512Hydroxy-PEG1-(CH2)2-Boc;化合物 T15512Hydroxy-PEG1-(CH2)2-Boc
Hydroxy-PEG1-(CH2)2-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].
价 格:¥电议型 号:T15512产 地:中国大陆
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T15511Hydroxy-PEG1-C2-methyl ester;化合物 T15511Methyl 3-(2-hydroxyethoxy)propanoate;Methyl 3-(2-hydroxyethox
Hydroxy-PEG1-C2-methyl ester is a polyethylene glycol (PEG) derived linker widely employed for the production of PROTACs - proteolysis targeting chimeras. [1]
价 格:¥电议型 号:T15511产 地:中国大陆
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T15510Hydroxy-PEG1-acid;化合物 T15510Hydroxy-PEG1-acid
Hydroxy-PEG1-acid is a non-cleavable 1-unit polyethylene glycol (PEG) linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15510产 地:中国大陆
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T1551Tegaserod maleate;马来酸替加色罗HTF-919|||SDZ-HTF-919;HTF-919|||马来酸替加色罗|||SDZ-HTF-919
Tegaserod maleate (SDZ-HTF-919) is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation. Its use was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating and constipation associated with irritable bowel syndrome. On March 30, 2007, the U.S. Food and Drug Administration requested that Novartis withdraw Zelnorm from shelves. The FDA alleges a relationship between pres
价 格:¥电议型 号:T1551产 地:中国大陆
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T15509Hydroxy-Amino-bis(PEG2-propargyl);化合物 T15509Hydroxy-Amino-bis(PEG2-propargyl)
Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-linked PROTAC linker employed for synthesizing PROTACs[1].
价 格:¥电议型 号:T15509产 地:中国大陆
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T15508Hydroxy-Amino-bis(PEG1-C2-Boc);化合物 T15508Hydroxy-Amino-bis(PEG1-C2-Boc)
Hydroxy-Amino-bis(PEG1-C2-Boc) is an alkyl/ether-based linker used for the synthesis of PROTACs[1].
价 格:¥电议型 号:T15508产 地:中国大陆
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T15507Hycanthone;海恩酮Etrenol(mesylate)|||Win 249-33;Etrenol(mesylate)|||Win 249-33|||海恩酮
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits APE1 via direct protein binding(KD: 10 nM).
价 格:¥电议型 号:T15507产 地:中国大陆
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T15506HTS01037;化合物 T15506HTS01037
HTS01037 is an inhibitor of fatty acid-binding. HTS01037 is a competitive antagonist of protein-protein interactions mediated by AFABP/aP2 (Ki: 0.67 μM).
价 格:¥电议型 号:T15506产 地:中国大陆
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T15505HSK0935;化合物 T15505HSK 0935|||HSK-0935;HSK 0935|||HSK-0935
HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has antihyperglycemic activities.
价 格:¥电议型 号:T15505产 地:中国大陆
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T15504HS-PEG6-CH2CH2-Boc;化合物 T15504HS-PEG6-CH2CH2-Boc
HS-PEG6-CH2CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15504产 地:中国大陆
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T15503HQL-79;化合物 T15503HQL-79
HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM). It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.
价 格:¥电议型 号:T15503产 地:中国大陆
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T15502HQ-415;化合物 T15502HQ-415
HQ-415 is a class of clinically relevant bioactive metal chelators related to clioquinol. The effective concentration eliciting an EC50 for HQ-415 is 15 μM.
价 格:¥电议型 号:T15502产 地:中国大陆
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T15501HPPH;光克洛Photochlor;光克洛|||Photochlor
HPPH (Photochlor) (Photochlor) is a second-generation photosensitizer. It is used as photodynamic therapy (PDT) agent.
价 格:¥电议型 号:T15501产 地:中国大陆
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T15500HPi1;化合物HPi1HPi1
HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri, Lactobacillus casei, and Bifidobacterium longum.
价 格:¥电议型 号:T15500产 地:中国大陆
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T1550Thiamphenicol;甲砜霉素Dextrosulphenidol|||Thiophenicol;甲砜霉素|||Dextrosulphenidol|||Thiophenicol
Thiamphenicol (Dextrosulphenidol) is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.
价 格:¥电议型 号:T1550产 地:中国大陆
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T15499HOOCCH2O-PEG4-CH2COOH;化合物 T15499HOOCCH2O-PEG4-CH2COOH
HOOCCH2O-PEG4-CH2COOH (compound 5), is a symmetric polyethylene glycol (PEG) linker. It is primarily utilized in the synthesis of the initial Homo-PROTAC[1] compound.
价 格:¥电议型 号:T15499产 地:中国大陆
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T15498HOKU-81;化合物 T154984-Hydroxytulobuterol;4-Hydroxytulobuterol
HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.
价 格:¥电议型 号:T15498产 地:中国大陆
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T15495HOE 32020;化合物 T15495HOE 32020
HOE 32020 is a Hoechst stain, a blue fluorescent dyes, used to stain DNA. Hoechst dyes are soluble in water and in organic solvents such as dimethyl formamide or dimethyl sulfoxide. Concentrations can be achieved of up to 10 mg/mL. Aqueous solutions are stable at 2-6°C for at least six months when protected from light. For long-term storage the solutions are instead frozen at ≤-20°C.
价 格:¥电议型 号:T15495产 地:中国大陆
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T15494HO-PEG8-CH2CH2COOH;化合物 T15494Hydroxy-PEG8-acid;Hydroxy-PEG8-acid
Hydroxy-PEG8-acid (HO-PEG8-CH2CH2COOH) is a PEG-based PROTAC linker employed for PROTAC synthesis[1].
价 格:¥电议型 号:T15494产 地:中国大陆