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T15453GW7647化合物GW76472-[[4-[2-[[环己基氨基)羰基](4-环己基丁基)氨基]乙基]苯基]硫基]-2-甲基丙酸
GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively).
价 格:¥电议型 号:T15453产 地:中国大陆
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T15452GW7604;化合物 T15452GW7604
GW7604 is an antiestrogen and it also is the metabolite of GW5638. GW5638 is an antagonist of high-affinity estrogen receptor (ER).
价 格:¥电议型 号:T15452产 地:中国大陆
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T15451GW-870086;化合物GW-870086GW-870086
GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB).
价 格:¥电议型 号:T15451产 地:中国大陆
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T15450GW-803430;化合物 T15450GW-3430;GW-3430
GW-803430 is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH R1) (pIC50: 9.3). GW-803430 is orally active in an animal model of obesity.
价 格:¥电议型 号:T15450产 地:中国大陆
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T1545Levamlodipine;左旋氨氯地平(S)-Amlodipine|||S-amlodipine;左旋氨氯地平|||(S)-Amlodipine|||S-amlodipine
Levamlodipine (S-amlodipine) belongs to the dihydropyridine group of calcium channel blockers. Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. The names S-amlodipine and levamlodipine may be used interchangeably as both substances are the same, however, with differing nomenclature. As a racemic mixture, amlodipine contains (R) and (S)-amlodipine isomers, but only (S)-amlodipine as the active moiet
价 格:¥电议型 号:T1545产 地:中国大陆
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T15449GW-406381化合物 T15449GW406381|||GW 406381
GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats following chronic constriction injury.
价 格:¥电议型 号:T15449产 地:中国大陆
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T15448GW-1100;化合物 T15448GW-1100
GW-1100 is a selective antagonist of GPR40 (pIC50: 6.9). GW1100 also plays the role of a GPR40 inverse agonist.
价 格:¥电议型 号:T15448产 地:中国大陆
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T15447Guacetisal;呱西替柳Guacetisal
Guacetisal is extracted from the esterification reaction of acetylsalicylic acid with guaiacol which can be used for research on the treatment of chronic bronchitis.
价 格:¥电议型 号:T15447产 地:中国大陆
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T15446GT 949;化合物GT 949GT 949
GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) (EC50: 0.26 nM).
价 格:¥电议型 号:T15446产 地:中国大陆
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T15444GSK962;化合物GSK962GSK962
GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.
价 格:¥电议型 号:T15444产 地:中国大陆
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T15443GSK8814;化合物 T15443GSK8814
GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan). GSK8814 displays 500-fold selectivity for ATAD2 over BRD4 BD1. GSK8814 binds to ATAD2 and BRD4 BD1 (pIC50s: 7.3 and 4.6).
价 格:¥电议型 号:T15443产 地:中国大陆
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T15442GSK864;化合物 T15442GSK864
GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).
价 格:¥电议型 号:T15442产 地:中国大陆
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T15441GSK8573;化合物GSK8573GSK8573
GSK8573 is an inactive control compound for GSK2801. GSK8573 has binding activity to BRD9 (Kd of 1.04 μM).
价 格:¥电议型 号:T15441产 地:中国大陆
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T15440GSK376501A;化合物GSK376501AGSK376501A
GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.
价 格:¥电议型 号:T15440产 地:中国大陆
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T1544Olsalazine disodium;奥沙拉秦钠Dipentum|||Olsalazine Sodium;Dipentum|||奥沙拉秦钠|||Olsalazine Sodium
Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
价 格:¥电议型 号:T1544产 地:中国大陆
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T15439GSK3395879;化合物 T15439GSK3395879
GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).
价 格:¥电议型 号:T15439产 地:中国大陆
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T15438GSK3186899;化合物GSK31868993,3,3-trifluoro-N-[4-[[3-[(2R)-2-methylmorpholin-4-yl]-1H-pyrazolo[3,4-d]pyr
GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.
价 格:¥电议型 号:T15438产 地:中国大陆
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T15437GSK3145095;化合物GSK3145095GSK3145095
GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.
价 格:¥电议型 号:T15437产 地:中国大陆
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T15436GSK2838232;化合物GSK2838232GSK2838232
GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.
价 格:¥电议型 号:T15436产 地:中国大陆
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T15435GSK2837808A;化合物GSK2837808AGSK2837808A
GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).
价 格:¥电议型 号:T15435产 地:中国大陆