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T11421Glutaminase-IN-1；谷氨酰胺酶抑制剂1CB839 derivative；CB839 derivative
Glutaminase-IN-1 (CB839 derivative), a novel 1,3,4-selenodiazepine renal-type glutaminase (KGA) variant inhibitor, showed antitumor activity in an aggressive H22 hepatocellular carcinoma xenograft model.
价 格：￥电议型 号：T11421产 地：中国大陆
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T11391LGepotidacin；化合物 T11391LGSK2140944；GSK2140944
Gepotidacin is a novel triazaacenaphthylene inhibitor of bacterial type II topoisomerase.
价 格：￥电议型 号：T11391L产 地：中国大陆
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T11391Gepotidacin S enantiomer；化合物 T11391GSK2140944 S enantiomer；GSK2140944 S enantiomer
Gepotidacin S enantiomer is an S enantionmer of gepotidacin.
价 格：￥电议型 号：T11391产 地：中国大陆
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T11330LFTI-2148；化合物 T11330LFTI-2148
FTI-2148 is an inhibitor of RAS C-terminal mimetic dual farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1) (IC50s: 1.4 nM and 1.7 μM, respectively).
价 格：￥电议型 号：T11330L产 地：中国大陆
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T11330FTI-2148 diTFA；化合物 T11330FTI-2148 diTFA
FTI-2148 diTFA, a dual inhibitor targeting both farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1), functions as a RAS C-terminal mimetic. It exhibits potent inhibitory capabilities with IC50 values of 1.4 nM for FT-1 and 1.7 μM for GGT-1, respectively.
价 格：￥电议型 号：T11330产 地：中国大陆
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T11321FR194738 free base；化合物FR194738 free baseFR194738 free base
FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.?
价 格：￥电议型 号：T11321产 地：中国大陆
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T11314Fosmanogepix；化合物 T11314APX001|||E1211；APX001|||E1211
Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This metabolism leads to the formation of the active moiety, APX001A. Fosmanogepix (APX001), with its ability to target the highly conserved Gwt1 fungal enzyme, holds great potential for the development of treatments against invasive fungal infections.
价 格：￥电议型 号：T11314产 地：中国大陆
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T1124Flumethasone氟米松氟米松|||Flumetasone|||RS-2177|||NSC-54702
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
价 格：￥电议型 号：T1124产 地：中国大陆
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T11221ERAP1-IN-1；化合物ERAP1-IN-1ERAP1-IN-1
ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substrates but competitively inhibits its activity toward a nonamer peptide representative of physiological substrates.
价 格：￥电议型 号：T11221产 地：中国大陆
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T11220ER21355；化合物 T11220ER21355
ER21355, utilized for the treatment of prostatic diseases, acts as a phosphodiesterase 5 (PDE5) inhibitor.
价 格：￥电议型 号：T11220产 地：中国大陆
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T11219Equisetin；化合物 T11219Equisetin
Equisetin, an N-methylserine-derived acyl tetramic acid isolated from the terrestrial fungus Fusarium equiseti NRRL 5537, functions as a Quorum-sensing inhibitor (QSI) that specifically attenuates QS-regulated virulence phenotypes in P. aeruginosa, presenting a potent lead for treating P. aeruginosa infections without hindering bacterial growth. This tetramate-containing natural product possesses antibiotic and cytotoxic properties, effectively inhibiting the growth of Gram-positive bacteria and
价 格：￥电议型 号：T11219产 地：中国大陆
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T11218ε-?Viniferin；Epsilon-白藜芦醇脱氢二聚体epsilon-Viniferin；epsilon-Viniferin|||Epsilon-白藜芦醇脱氢二聚体
ε-?Viniferin (epsilon-Viniferin) a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.
价 格：￥电议型 号：T11218产 地：中国大陆
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T11217Eplivanserin；依利色林SR-46349；依利色林|||SR-46349
Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.
价 格：￥电议型 号：T11217产 地：中国大陆
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T11216Eplivanserin (mixture)化合物 T11216Eplivanserin mixture|||SR-46349 (mixture)
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,
价 格：￥电议型 号：T11216产 地：中国大陆
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T11215Episilvestrol；化合物 T11215Episilvestrol
Episilvestrol is a specific eIF4A-targeting translation inhibitor, with antitumor activity. Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia silvestris.
价 格：￥电议型 号：T11215产 地：中国大陆
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T11214EPI-589；化合物 T11214EPI-589
EPI-589, a quinone derivative and oxidoreductase enzyme inhibitor, is considered safe and well tolerated, showing promise for the treatment of amyotrophic lateral sclerosis (ALS).
价 格：￥电议型 号：T11214产 地：中国大陆
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T11213LEpertinib；化合物 T11213LS-22611；S-22611
Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM). It displays a strong antitumor activity.
价 格：￥电议型 号：T11213L产 地：中国大陆
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T11213Epertinib hydrochloride；化合物Epertinib hydrochlorideS-22611 hydrochloride；S-22611 hydrochloride
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
价 格：￥电议型 号：T11213产 地：中国大陆
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T11212EPAC 5376753；化合物EPAC 53767535-{[5-(2,4-dichlorophenyl)furan-2-yl]methylidene}-2-thioxodihydropyrimid
EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 ?M in Swiss 3T3 cells.
价 格：￥电议型 号：T11212产 地：中国大陆
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T11211EP4 receptor antagonist 1；化合物EP4 receptor antagonist 1EP4 receptor antagonist 1
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and 16.2 nM, respectively, while displaying minimal activity (IC50s >10 μM) against human EP1, EP2, and EP3 receptors.
价 格：￥电议型 号：T11211产 地：中国大陆
