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T10846CMLD010509；化合物 T10846SDS-1-021；SDS-1-021
CMLD010509 (SDS-1-021) is a highly selective inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MDM2, CCND1, MYC, MAF, and MCL-1.
价 格：￥电议型 号：T10846产 地：中国大陆
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T10821Cirsiliol；化合物 T10821Cirsiliol
Cirsiliol is a selective inhibitor of 5-lipoxygenase and a competitive low-affinity ligand of benzodiazepine receptors.
价 格：￥电议型 号：T10821产 地：中国大陆
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T10792LCHK1-IN-4 hydrochloride；化合物CHK1-IN-4盐酸盐CHK1-IN-4 hydrochloride（2120398-41-4 Free base）；CHK1-IN-4 hyd
CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1). CHK1-IN-4 hydrochloride potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 hydrochloride has anti-tumor activity.
价 格：￥电议型 号：T10792L产 地：中国大陆
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T10721CD73-IN-1；CD73 抑制剂1CD73-IN-1
CD73-IN-1 is a CD73 inhibitor with anticancer activity.
价 格：￥电议型 号：T10721产 地：中国大陆
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T10716CCR7 Ligand 1；化合物 T10716CCR7-Cmp2105；CCR7-Cmp2105
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.
价 格：￥电议型 号：T10716产 地：中国大陆
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T10639C-021 dihydrochloride；化合物C-021 dihydrochlorideC-021 dihydrochloride
C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.
价 格：￥电议型 号：T10639产 地：中国大陆
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T10621Bromodomain inhibitor-8；化合物 T10621Bromodomain inhibitor-8
Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.
价 格：￥电议型 号：T10621产 地：中国大陆
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T10567BMS-214662；化合物 T10567BMS-214662
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors, and has the ability to selectively target CML stem cells/progenitors with antitumor activity.
价 格：￥电议型 号：T10567产 地：中国大陆
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T10562(4-Acetamidocyclohexyl) nitrate；化合物 T10562BM121307；BM121307
(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.
价 格：￥电议型 号：T10562产 地：中国大陆
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T10538LBI-9321 trihydrochloride；化合物 T10538LBI-9321 trihydrochloride
BI-9321 trihydrochloride is a selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist (Kd: 166 nM). BI-9321 is inactive against NSD2-PWWP1 and NSD3-PWWP2.
价 格：￥电议型 号：T10538L产 地：中国大陆
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T10538BI-9321；化合物 T10538BI-9321
BI-9321 is a selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist (Kd: 166 nM). BI-9321 is inactive against NSD2-PWWP1 and NSD3-PWWP2.
价 格：￥电议型 号：T10538产 地：中国大陆
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T10521ODM-207；化合物BET-IN-4BET-IN-4|||ODM207；BET-IN-4|||ODM207
ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.
价 格：￥电议型 号：T10521产 地：中国大陆
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T10421AVE5688；化合物AVE5688AVE5688
AVE5688 is an inhibitor of glycogen phosphorylase (GP, IC50s: 430 nM and 915 nM; Kds: 170 nM and 530 nM for rmGPb and rmGPa). It can be used for the research of type 2 diabetes.
价 格：￥电议型 号：T10421产 地：中国大陆
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T1038Fludarabine；氟达拉滨NSC 118218|||Fludarabinum|||F-ara-A；NSC 118218|||Fludarabinum|||氟达拉宾|||氟达拉滨|||F-ara-
Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and lymphoma.
价 格：￥电议型 号：T1038产 地：中国大陆
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T10364Arbutamine；阿布他明GP 21213；GP 21213
Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be used to study cardiac stress and coronary artery disease
价 格：￥电议型 号：T10364产 地：中国大陆
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T10344AP521；化合物 T10344AP521
AP521 is an agonist of the human 5-HT1A receptor (IC50: 94 nM).
价 格：￥电议型 号：T10344产 地：中国大陆
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T10276LAKT Kinase Inhibitor HCl；AKT Kinase抑制剂盐酸盐AKT Kinase Inhibitor HCl(842148-40-7 Free base)；AKT Kinase
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.
价 格：￥电议型 号：T10276L产 地：中国大陆
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T1024Roflumilast；罗氟司特B9302-107|||BYK 20869|||APTA 2217|||BY 217；罗氟司特|||B9302-107|||BYK 20869|||APTA 2217|
Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3´, 5´-adenosine monophosphate (cAMP) and cAMP-mediated signaling.
价 格：￥电议型 号：T1024产 地：中国大陆
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T10225ABT-546；化合物 T10225A-216546；A-216546
ABT-546 (A-216546) is a potent, highly selective, and active endothelin ETA receptor antagonist with a Ki of 0.46 nM for [125I]endothelin-1 binding to cloned human endothelin ETA.
价 格：￥电议型 号：T10225产 地：中国大陆
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T10221LAbeprazan；化合物 T10221LDWP14012|||Abeprazan|||DWP-14012|||DWP14012|||DWP 14012|||DWP14012|||Abeprazan；
Abeprazan (DWP14012) is a potassium-competitive acid blocker and it is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases[1]. Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required.
价 格：￥电议型 号：T10221L产 地：中国大陆
