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T28862ST-168;化合物 T28862ST168|||ST 168;ST168|||ST 168
ST-168 is a potent inhibitor of PI3K and MEK. ST-168 displays improved PI3K and MEK1 isoform inhibition. ST-168 demonstrated a 2.8-, 2.7-, 23-, and 2.5-fold improved inhibition toward the PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ isoforms and a 2.2-fold improvement in MEK1 inhibition respectively, as compared to a previous lead ST-162 in in vitro enzymatic inhibition assays. ST-168 demonstrated superior tumoricidal efficacy over ST-162 in an A375 melanoma spheroid tumor model.
价 格:¥电议型 号:T28862产 地:中国大陆
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T28852SRI-31040;化合物 T28852SRI 31040;SRI 31040
SRI-31040 is a potent DAT allosteric modulator. It partially inhibits DAT uptake without altering DAT-mediated reverse transport and with minimal inhibition of DAT binding.
价 格:¥电议型 号:T28852产 地:中国大陆
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T28842SQ-24,798;化合物 T28842SQ 24,798|||SQ24,798;SQ 24,798|||SQ24,798
SQ-24,798 is an inhibitor of the thrombin-activatable fibrinolysis and carboxypeptidase N (CPN).
价 格:¥电议型 号:T28842产 地:中国大陆
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T28832SPC-839;化合物 T28832SPC-839
SPC-839 is an IKK-2 Inhibitor with oral activity.
价 格:¥电议型 号:T28832产 地:中国大陆
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T28822SNAP 398299;化合物 T28822SNAP-398299|||SNAP398299;SNAP-398299|||SNAP398299
SNAP 398299, a galanin receptor antagonist, is a potential novel pharmacological treatment for mood disorders.
价 格:¥电议型 号:T28822产 地:中国大陆
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T28812SM-130686;化合物 T28812SM 130686|||SM130,686|||SM 130,686;SM 130686|||SM130,686|||SM 130,686
SM-130,686 is a potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth hormone secretagogue. It has around half the potency of the endogenous agonist ghrelin as a stimulator of growth hormone release.
价 格:¥电议型 号:T28812产 地:中国大陆
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T28802SLC4101431;化合物 T28802SLC-4101431|||SLC 4101431;SLC-4101431|||SLC 4101431
SLC4101431 is a potent SphK2 inhibitor with Ki value of 90 nM.
价 格:¥电议型 号:T28802产 地:中国大陆
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T28792SKF-75670 Hydrobromide;化合物 T28792SKF75670 Hydrobromide|||SKF-75670|||SKF75670 HBr|||SKF 75670;SKF756
SKF-75670 hydrobromide is an atypical D1DR (dopamine receptor) agonist. It displays agonist activity in vivo and antagonist activity in vitro.
价 格:¥电议型 号:T28792产 地:中国大陆
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T28782Sinoporphyrin sodium;化合物 T28782sinoporphyrin|||DVDMS Free|||DVDMS;sinoporphyrin|||DVDMS Free|||DVDMS
Sinoporphyrin sodium significantly suppressed cell proliferation, promoted early apoptotic response, triggered collapse of F-actin filaments and inhibited cell migration. Sinoporphyrin sodium potentially a treatment for cancer. Sinoporphyrin sodium is also a photosensitizer.
价 格:¥电议型 号:T28782产 地:中国大陆
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T28773SI-2;化合物SI-2SI2|||EPH 116|||EPH116|||EPH-116;SI2|||EPH 116|||EPH116|||EPH-116
SI-2 is an inhibitor (SMI) of steroid receptor coactivator-3 (SRC-3 or AIB1). SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability.
价 格:¥电议型 号:T28773产 地:中国大陆
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T28752Senazodan hydrochloride;化合物 T28752Senazodan HCl|||MCI-154|||MCI154|||MCI 154;Senazodan HCl|||MCI-154
Senazodan HCl, a phosphodiesterase inhibitor, is used potentially for the treatment of heart failure.
价 格:¥电议型 号:T28752产 地:中国大陆
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T28742Securinine mononitrate;化合物 T28742Securinan-11-one nitrate;Securinan-11-one nitrate
Securinine mononitrate is a cholinergic agent and an antagonist of gamma-aminobutyric acid A (GABAA) receptor.
价 格:¥电议型 号:T28742产 地:中国大陆
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T28732SCH-538415;化合物 T28732SCH-538415
SCH-538415 is an inhibitor of acyl carrier protein synthase from a microorganism. SCH-538415 exhibited inhibitory activity in the acyl carrier protein synthase (AcpS) assay with an IC(50) value of 4.19 microM and showed antibacterial activity against Staphylococcus aureus in the agar diffusion assay.
价 格:¥电议型 号:T28732产 地:中国大陆
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T28712Sch 31828;化合物 T28712Sch31828|||Sch-31828;Sch31828|||Sch-31828
Sch 31828 is an antibiotic from Microbispora.
价 格:¥电议型 号:T28712产 地:中国大陆
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T28702SC-68376;化合物 T28702SC 68376;SC 68376
SC-68376 is a potent, reversible, cell-permeable, ATP-competitive, and selective inhibitor of p38 MAP kinase.
价 格:¥电议型 号:T28702产 地:中国大陆
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T28692SB-436811;化合物 T28692SB 436811;SB 436811
SB-436811 is an antagonist of human urotensin-II receptor.
价 格:¥电议型 号:T28692产 地:中国大陆
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T28672SB 207710;化合物 T28672SB-207710|||SB207710;SB-207710|||SB207710
SB 207710 is a selective and high affinity antagonist of 5-HT4 receptor.
价 格:¥电议型 号:T28672产 地:中国大陆
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T28652S6K1-IN-DG2;S6K1抑制剂DG2S6K1 Inhibitor DG2|||S6K1-Inhibitor-DG2|||S6K1 IN DG2|||S6K1INDG2|||S6K1Inhibi
S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.
价 格:¥电议型 号:T28652产 地:中国大陆
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T26371(2S,3R)-LP99;化合物 T26371(2S,3R)-LP99
(2S,3R)-LP99 is a less active enantiomer of LP99.
价 格:¥电议型 号:T26371产 地:中国大陆
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T26312Uredofos;化合物 T26312Sansalid|||RH 32565|||RH32565|||RH-32565;Sansalid|||RH 32565|||RH32565|||RH-32565
Uredofos is a broad-spectrum dewormer which canine tapeworms, roundworms, hookworms and whipworms are very effective.
价 格:¥电议型 号:T26312产 地:中国大陆