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T16822S-Acetyl-PEG3-C2-acid;化合物 T16822S-Acetyl-PEG3-C2-acid
S-Acetyl-PEG3-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T16822产 地:中国大陆
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T16752Rimacalib化合物 T16752SMP 114
Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).
价 格:¥电议型 号:T16752产 地:中国大陆
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T15552Iferanserin;化合物 T15552S-MPEC;S-MPEC
Iferanserin (S-MPEC) is a selective antagonist of the 5-HT receptor (serotonin receptor) with an affinity for 5-HT2A receptors. Iferanserin has the potential for internal hemorrhoid disease treatment.
价 格:¥电议型 号:T15552产 地:中国大陆
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T15172DSHS00884;化合物 T15172SSYA10-001;SSYA10-001
DSHS00884 is a potent inhibitor of human papillomavirus E6 (IC50: 10 μM).
价 格:¥电议型 号:T15172产 地:中国大陆
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T13892SNIPER(TACC3)-2;化合物 T13892SNIPER(TACC3)-2
SNIPER(TACC3)-2 targets TACC3 protein degradation via the ubiquitin-proteasome pathway. It induces cancer cell death.
价 格:¥电议型 号:T13892产 地:中国大陆
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T13882SCH00013;化合物 T13882SCH00013
SCH00013 is an agent of cardiotonic that primarily acts via an increase in myofibrillar Ca++ sensitivity. SCH00013 have a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4.
价 格:¥电议型 号:T13882产 地:中国大陆
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T13424(1R,2S)-VU0155041;化合物(1R,2S)-VU0155041(1R,2S)-VU0155041
(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.
价 格:¥电议型 号:T13424产 地:中国大陆
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T13052S2101化合物 T13052S 2101
S 2101 is an inhibitor of lysine-specific demethylase 1 (LSD1)(IC50 of 0.99 μM, Ki of 0.61 μM and Kinact/Ki of 4560 M/s).
价 格:¥电议型 号:T13052产 地:中国大陆
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T13042SWE101;化合物 T13042SWE101
SWE101 is a potent human and rat soluble epoxide hydrolase (sEH)-P inhibitor(IC50s of 4 μM and 2.8 μM, respectively).
价 格:¥电议型 号:T13042产 地:中国大陆
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T13032Sulfamonomethoxine-d4;化合物 T13032Sulfamonomethoxine-d4
Sulfamonomethoxine D4 is a deuterium labeled Sulfamonomethoxine. Sulfamonomethoxine is an agent of long acting sulfonamide antibacterial, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
价 格:¥电议型 号:T13032产 地:中国大陆
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T13022SSTR5 antagonist 2;化合物 T13022SSTR5 antagonist 2
SSTR5 antagonist 2 is a highly potent, oral active and selective antagonist of somatostatin (receptor) subtype 5 (SSTR5),with potential to treat type 2 diabetes mellitus (T2DM).
价 格:¥电议型 号:T13022产 地:中国大陆
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T13002SSR-241586;化合物 T13002SSR-241586
SSR-241586 is a neurokinin receptors antagonist,and is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS).
价 格:¥电议型 号:T13002产 地:中国大陆
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T12982SP4206;化合物 T12982SP4206
SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)
价 格:¥电议型 号:T12982产 地:中国大陆
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T12972Solenopsin;化合物 T12972Solenopsin
Solenopsin is an ATP-competitive inhibitor of AKT(IC50 : 10 μM) .
价 格:¥电议型 号:T12972产 地:中国大陆
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T12942SN50;化合物 T12942SN50
SN50 is a cell permeable NF-κB translocation inhibitor.
价 格:¥电议型 号:T12942产 地:中国大陆
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T12941SN 2;化合物SN 2SN 2
SN 2 is a novel and potent TRPML3 ion channel activator(EC50 = 1.13 μM). SN 2 also shares a similar antiviral effect against DENV2 and ZIKV.
价 格:¥电议型 号:T12941产 地:中国大陆
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T12932SM-164 Hydrochloride (957135-43-2 free base);化合物 T12932SM-164 Hydrochloride;SM-164 Hydrochloride
SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP.
价 格:¥电议型 号:T12932产 地:中国大陆
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T12919SIRT-IN-2;化合物SIRT-IN-2SIRT-IN-2
SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).
价 格:¥电议型 号:T12919产 地:中国大陆
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T12911Sigma-1 receptor antagonist 2;化合物Sigma-1 receptor antagonist 2Sigma-1 receptor antagonist 2
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
价 格:¥电议型 号:T12911产 地:中国大陆
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T12892SGL5213;化合物 T12892SGL5213
SGL5213 is an oral active and low-absorbable inhibitor of sodium-dependent glucose cotransporter 1 (SGLT1)(hSGLT1 and hSGLT2 with IC50 values of 29 nM and 20 nM , respectively),and has potential to treat type 2 diabetes.
价 格:¥电议型 号:T12892产 地:中国大陆