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T20107Ertapenem;化合物 T20107Invanz|||MK0826|||MK-0826|||MK 0826;Invanz|||MK0826|||MK-0826|||MK 0826
Ertapenem is a parenteral carbapenem. It has a broad spectrum of antimicrobial activity. It is highly resistant to inactivation by a wide variety of beta-lactamases.
价 格:¥电议型 号:T20107产 地:中国大陆
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T19948Grazoprevir potassium salt;化合物 T19948MK 5172 potassium|||Grazoprevir|||Grazoprevir potassium|||MK 51
Grazoprevir is a drug approved for the treatment of hepatitis C. Grazoprevir is a second-generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets.
价 格:¥电议型 号:T19948产 地:中国大陆
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T19674Verlukast;化合物 T19674MK 0679|||MK-679|||L 668,019|||MK 679|||L 668019|||L-668,019;MK 0679|||MK-679|||
Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homogenates and dimethyl sulfoxide differentiated U937 cell membrane preparations (IC50 = 10.7 +/- 1.6 nM) but is essentially inactive versus [3H]leukotriene C4 binding in guinea-pig lung homogenates (IC50: 19 and 33 microM).
价 格:¥电议型 号:T19674产 地:中国大陆
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T1952MK-2206 dihydrochloride;化合物MK-2206 dihydrochlorideMK-2206 2HCl;MK-2206 2HCl
MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor activity.
价 格:¥电议型 号:T1952产 地:中国大陆
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T19430Indacrinone;茚达立酮MK-196|||Indacrynic acid;MK-196|||Indacrynic acid|||茚达立酮
Indacrinone is an investigational diuretic.
价 格:¥电议型 号:T19430产 地:中国大陆
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T19429MK-6240;化合物 T19429MK-6240
MK-6240 is a tau positron emission tomography (PET) tracer for neurofibrillary tangles (NFTs). MK-6240 exhibits high specificity and selectivity for binding to NFTs.
价 格:¥电议型 号:T19429产 地:中国大陆
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T1928Anacetrapib;安塞曲匹MK-0859;安塞曲匹|||MK-0859
Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels.
价 格:¥电议型 号:T1928产 地:中国大陆
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T1913MK-3697;化合物MK3697MK-3697
MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).
价 格:¥电议型 号:T1913产 地:中国大陆
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T1872Fenretinide;芬维A胺4-HPR|||MK-4016|||4-hydroxy(phenyl)retinamide;4-HPR|||MK-4016|||芬维A胺|||4-hydroxy(phe
Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.
价 格:¥电议型 号:T1872产 地:中国大陆
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T1799Caspofungin Acetate;醋酸卡泊芬净L 743873|||Cancidas|||MK 0991|||L 743872;醋酸卡泊芬净|||L 743873|||Cancidas|||MK
Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species.
价 格:¥电议型 号:T1799产 地:中国大陆
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T1790Fosaprepitant dimeglumine;福沙吡坦二甲葡胺L785298|||MK-0517|||Fosaprepitant dimeglumine salt;福沙匹坦二甲葡胺|||L785
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.
价 格:¥电议型 号:T1790产 地:中国大陆
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T1743Aprepitant;阿瑞匹坦MK-869|||MK-0869|||L-754030|||Aprepitant`;MK-869|||MK-0869|||阿瑞匹坦|||L-754030|||Aprepi
Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.
价 格:¥电议型 号:T1743产 地:中国大陆
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T1734LRizatriptan化合物 T1734LMK 462 free base|||Risatriptan
Rizatriptan is an agonist of the serotonin-1b and serotonin-1d receptor.
价 格:¥电议型 号:T1734L产 地:中国大陆
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T17194Ubrogepant;化合物UbrogepantMK-1602;MK-1602
Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.
价 格:¥电议型 号:T17194产 地:中国大陆
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T16782Rolofylline;洛罗茶碱KW-3902|||MK-7418|||KF-15372;KW-3902|||MK-7418|||KF-15372
Rolofylline (KW-3902) is a selective adenosine A1 receptor antagonist used in the study of acute congestive heart failure and renal dysfunction, and in the study of neurodegenerative disorders.
价 格:¥电议型 号:T16782产 地:中国大陆
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T1677LMontelukast sodium孟鲁司特钠MK0476|||孟鲁司特钠
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.
价 格:¥电议型 号:T1677L产 地:中国大陆
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T16683Pumosetrag Hydrochloride化合物 T16683MKC-733|||DDP-733
Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
价 格:¥电议型 号:T16683产 地:中国大陆
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T16679Belzutifan;化合物BelzutifanPT2977|||MK-6482;PT2977|||MK-6482
Belzutifan (MK-6482) is a potential treatment for clear cell renal cell carcinoma (ccRCC). Belzutifan is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). Belzutifan , as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
价 格:¥电议型 号:T16679产 地:中国大陆
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T1627Famotidine;法莫替丁MK-208;MK-208|||法莫替丁
Famotidine (MK-208) is a propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.
价 格:¥电议型 号:T1627产 地:中国大陆
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T16100Balamapimod;化合物 T16100MKI 833;MKI 833
Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.
价 格:¥电议型 号:T16100产 地:中国大陆