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T16099MK8722;化合物MK8722MK8722
MK8722 is an effective and systemic activator of pan-AMPK.
价 格:¥电议型 号:T16099产 地:中国大陆
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T16098Islatravir;化合物IslatravirMK-8591;MK-8591
Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively).
价 格:¥电议型 号:T16098产 地:中国大陆
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T16097MK-8318;化合物 T16097MK-8318
MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).
价 格:¥电议型 号:T16097产 地:中国大陆
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T16096Filorexant;化合物FilorexantMK-6096;MK-6096
Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).
价 格:¥电议型 号:T16096产 地:中国大陆
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T16095MK-4256化合物 T16095MK 4256|||MK4256
MK-4256 is an effective and selective SSTR3 antagonist (IC50s: 0.66 nM and 0.36 nM in human and mouse receptor binding assays, respectively).
价 格:¥电议型 号:T16095产 地:中国大陆
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T16094MK-3328;化合物MK-3328MK-3328
MK-3328 has a high affinity for β-Amyloid (IC50:10.5 nM), and can be used as a candidate PET ligand for clinical assessment of β-amyloid plaque load. MK-3328 is a potential treatment for Alzheimer´s disease.
价 格:¥电议型 号:T16094产 地:中国大陆
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T16093Telcagepant化合物 T16093MK-0974
Telcagepant is an orally active antagonist of calcitonin gene-related peptide (CGRP) receptor (Kis: 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively).
价 格:¥电议型 号:T16093产 地:中国大陆
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T16091MK-0812 Succinate;化合物MK-0812 SuccinateMK-0812 Succinate
MK-0812 Succinate is an effective and selective CCR2 antagonist.
价 格:¥电议型 号:T16091产 地:中国大陆
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T16090LMK-0773 FA;MK-0773 甲酸盐MK-0773 FA (606101-58-0 Free base);MK-0773 FA (606101-58-0 Free base)
MK-0773 FA (MK-0773 FA (606101-58-0 Free base)) is a selective androgen receptor modulator with an IC50 value of 6.6 nM for AR, which can be used for the prevention and treatment of cancer-related muscle wasting.
价 格:¥电议型 号:T16090L产 地:中国大陆
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T16090MK-0773;化合物 MK-0773PF-05314882;PF-05314882
MK-0773 (PF-05314882) is a selective androgen receptor modulator that binds to AR (IC50: 6.6 nM) for the study of diseases caused by endocrine abnormalities.
价 格:¥电议型 号:T16090产 地:中国大陆
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T16089MK-0674;化合物 MK-0674MK-0674
MK-0674 is an orally available, selective and potent cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S. It can be used in metabolism-related diseases.
价 格:¥电议型 号:T16089产 地:中国大陆
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T16088MK-0608;化合物MK-0608MK-0608
MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay).
价 格:¥电议型 号:T16088产 地:中国大陆
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T16087Quiflapon;喹夫拉朋MK-591;喹夫拉朋|||MK-591
Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotriene biosynthesis (LT) inhibitor (IC50: 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively).
价 格:¥电议型 号:T16087产 地:中国大陆
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T16086MK-0493;化合物 T16086MK-0493
MK-0493 is an effective and selective agonist of the melanocortin receptor 4 (MC4R). It also demonstrated significant reductions in energy intake.
价 格:¥电议型 号:T16086产 地:中国大陆
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T16085MK-0429化合物 T16085L-000845704
MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).
价 格:¥电议型 号:T16085产 地:中国大陆
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T16084MK-0343化合物 T16084MRK-409
MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.
价 格:¥电议型 号:T16084产 地:中国大陆
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T1605Enalapril依那普利MK-421|||依那普利
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
价 格:¥电议型 号:T1605产 地:中国大陆
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T15942MK-7622;化合物MK-7622M1 receptor modulator;M1 receptor modulator
MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.
价 格:¥电议型 号:T15942产 地:中国大陆
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T1583Vorinostat伏立诺他MK0683|||伏立诺他|||suberoylanilide hydroxamic acid|||SAHA
Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and induces apoptosis.
价 格:¥电议型 号:T1583产 地:中国大陆
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T1574Etoricoxib;依托考昔Arcoxia|||MK-663|||Tauxib|||L-791456|||Nucoxia|||Desvenlafaxine;Arcoxia|||MK-663|||Ta
Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
价 格:¥电议型 号:T1574产 地:中国大陆