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T64079Mutant p53 modulator-1;化合物 Mutant p53 modulator-1Mutant p53 modulator-1
Mutant p53 modulator-1 is a mutant p53 modulator. mutant p53 modulator-1 is able to hinder the progression of cancers containing p53 mutations.
价 格:¥电议型 号:T64079产 地:中国大陆
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T63967Multi-kinase-IN-2;化合物 Multi-kinase-IN-2Multi-kinase-IN-2
Multi-kinase-IN-2 is an orally active inhibitor of angiokinases. multi-kinase-IN-2 significantly inhibits the activity of angiokinases such as VEGFR-1/2/3, PDGFRα/β, FGFR-1, LYN and c-KIT kinases. -IN-2 significantly attenuates phosphorylation of AKT and ERK proteins, induces apoptosis and has anticancer effects.
价 格:¥电议型 号:T63967产 地:中国大陆
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T63955MU1656;化合物 MU1656MU1656
MU1656, a potent and selective histone methyltransferase DOT1L inhibitor, demonstrates an IC50 of 2 nM. It is applicable in the research of hematological malignancies [1].
价 格:¥电议型 号:T63955产 地:中国大陆
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T63870Multi-kinase-IN-3;化合物 Multi-kinase-IN-3Multi-kinase-IN-3
Multi-kinase-IN-3 (compound 2) is a potent inhibitor of angiokinase and inhibits VEGFR-2 (IC50: 58.3 nM) and PDGFRβ (IC50: 55 nM).
价 格:¥电议型 号:T63870产 地:中国大陆
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T63793Tauro-ω-muricholic acid sodium;化合物 Tauro-ω-muricholic acid sodiumTauro-ω-muricholic acid sodium
Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid of hepatic origin. Tauro-ω-muricholic acid sodium can be used as a serum marker for early onset neonatal sepsis (EOS) and biliary stasis.
价 格:¥电议型 号:T63793产 地:中国大陆
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T63650Samuraciclib hydrochloride hydrate;化合物 Samuraciclib hydrochloride hydrateSamuraciclib hydrochloride
Samuraciclib (CT7001) hydrochloride hydrate is a potent, selective, ATP-competitive, orally active inhibitor of CDK7 (IC50: 41 nM). Samuraciclib hydrochloride hydrate inhibits the growth of breast cancer cell lines (GI50: 0.2-0.3 μM) and exhibits potent antitumor effects.
价 格:¥电议型 号:T63650产 地:中国大陆
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T62988Mufemilast;化合物 MufemilastMufemilast
Mufemilast is an inhibitor of phosphodiesterase 4 (PDE4).
价 格:¥电议型 号:T62988产 地:中国大陆
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T62768Mu opioid receptor antagonist 4;化合物 Mu opioid receptor antagonist 4Mu opioid receptor antagonist 4
Mu opioid receptor antagonist 4 (compound 31) is a potent and selective mu opioid receptor (MOR) antagonist that permeates the blood-brain barrier (Ki: 0.38 nM, EC50: 0.38 nM). Mu opioid receptor antagonist 2 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62768产 地:中国大陆
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T62767Mu opioid receptor antagonist 3;化合物 Mu opioid receptor antagonist 3Mu opioid receptor antagonist 3
Mu opioid receptor antagonist 3 (compound 26) is a potent and selective mu opioid receptor (MOR) antagonist that penetrates the blood-brain barrier (Ki: 0.24 nM, EC50: 0.54 nM). Mu opioid receptor antagonist 2 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62767产 地:中国大陆
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T62766Mu opioid receptor antagonist 2;化合物 Mu opioid receptor antagonist 2Mu opioid receptor antagonist 2
Mu opioid receptor antagonist 2 (compound 25) is a potent and selective mu opioid receptor (MOR) antagonist that permeates the blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM). Mu opioid receptor antagonist 2 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62766产 地:中国大陆
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T62673Mu opioid receptor antagonist 5;化合物 Mu opioid receptor antagonist 5Mu opioid receptor antagonist 5
Mu opioid receptor antagonist 5 (compound NAP) is a selective mu opioid receptor (MOR) antagonist that crosses the blood-brain barrier (EC50: 1.14 nM, Ki: 0.37 nM). Mu opioid receptor antagonist 5 can be used to study opioid use disorder (OUD).
价 格:¥电议型 号:T62673产 地:中国大陆
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T6234Ambroxol hydrochloride;盐酸氨溴索Mucosolvan|||Mucoangin|||Ambroxol HCl;Mucosolvan|||Mucoangin|||盐酸氨溴索|||A
Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
价 格:¥电议型 号:T6234产 地:中国大陆
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T61835Samuraciclib;化合物 SamuraciclibSamuraciclib
Samuraciclib (CT7001) is a potent, selective, and orally active inhibitor of CDK7, with an ATP-competitive nature. It effectively inhibits CDK7 with an IC 50 value of 41 nM. Furthermore, Samuraciclib demonstrates remarkable selectivity ratios, with 45-fold, 15-fold, 230-fold, and 30-fold selectivity over CDK1, CDK2 (IC 50 of 578 nM), CDK5, and CDK9, respectively. Notably, Samuraciclib has been found to inhibit the growth of breast cancer cell lines, exhibiting GI 50 values ranging between 0.2-0.
价 格:¥电议型 号:T61835产 地:中国大陆
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T61802AK-778-XXMU;化合物 AK-778-XXMUAK-778-XXMU
AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.
价 格:¥电议型 号:T61802产 地:中国大陆
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T61661LY3372689;化合物LY3372689Formulaic Ia;Formulaic Ia
LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer´s disease.
价 格:¥电议型 号:T61661产 地:中国大陆
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T61320Immunoproteasome inhibitor 1;化合物 Immunoproteasome inhibitor 1Immunoproteasome inhibitor 1
Immunoproteasome inhibitor 1 is a highly potent and reversible inhibitor of both immunoproteasome and proteasome activity. It exhibits time-independent inhibitory effects on immunoproteasome subunits β5c, β1i, and β5i, with respective Ki values of 1.18 μM, 0.27 μM, and 1.91 μM. This compound shows promising potential for the treatment of select neoplastic diseases [1].
价 格:¥电议型 号:T61320产 地:中国大陆
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T6124Mubritinib;木利替尼TAK-165;木利替尼|||TAK-165
Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
价 格:¥电议型 号:T6124产 地:中国大陆
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T61067MurB-IN-1;化合物 MurB-IN-1MurB-IN-1
MurB-IN-1 (compound 44) is a potent inhibitor of MurB, an essential enzyme involved in the synthesis of bacterial cell wall. With a binding affinity of K d 3.57 μM, MurB-IN-1 effectively hinders the activity of MurB, presenting a promising therapeutic option against P. aeruginosa, a highly virulent and opportunistic pathogen associated with severe infections and mortality [1].
价 格:¥电议型 号:T61067产 地:中国大陆
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T60927Ranimustine;化合物 RanimustineRanimustine
Ranimustine (MCNU) can be used for polycythemia vera and chronic myelogenous leukemia research, which is a nitrosourea alkylating agent [1] [3] [4].
价 格:¥电议型 号:T60927产 地:中国大陆
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T60635Simufilam hydrochloride;化合物 Simufilam hydrochlorideSimufilam hydrochloride
Simufilam (PTI-125) (hydrochloride) is an orally active filamin A (FLNA) activator with low toxicity that can be used in the Alzheimer´s disease research. Simufilam (hydrochloride) preferentially binds to altered FLNA and restores its native conformation, restores receptor and synaptic activities, and reduces its a7nAChR/TLR4 associations and downstream pathologies [1].
价 格:¥电议型 号:T60635产 地:中国大陆