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产品数:86101
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T8762SW106065cell,SW 106065,cdk4,Inhibitor,MPNST,cycle,ATP,anticancer,cdk6,cyclin,SW106065,Apoptosis,inhi
SW-106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors).SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). It inhibits ATP consumption of sMPNST and other models of MPNST with an EC50 of 1 μM. SW106065 can be used for MPNST research
价 格:¥电议型 号:T8762产 地:中国大陆
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T6759AP-III-a4Inhibitor,AP-III-a-4,Phosphopyruvate hydratase,Apoptosis,inhibit,antidiabetic,anticancer,HC
AP-III-a4 (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.
价 格:¥电议型 号:T6759产 地:中国大陆
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T6787BIO-acetoximeBIO acetoxime,Glycogen synthase kinase 3,inhibit,BIO-acetoxime,Herpes simplex virus,Gly
BIO-acetoxime is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.
价 格:¥电议型 号:T6787产 地:中国大陆
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T7869N-(Hydroxymethyl)nicotinamideBacterial,Inhibitor,antimicrobic,N(Hydroxymethyl)nicotinamide,N (Hydrox
Nicoform is an antimicrobial agent.
价 格:¥电议型 号:T7869产 地:中国大陆
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T21588OlomoucineOlomoucine,Inhibitor,cyclindependent kinases,cdc2,purines,cell cycle,non-small cell lung c
Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 ?M, respectively. Olomoucine regulates cell cycle and exhibits anti-melanin tumor activities.
价 格:¥电议型 号:T21588产 地:中国大陆
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T8820BML-284 hydrochlorideBML284 hydrochloride,AGS,TCF,N-cadherin,Wnt,BML284,cardiac defect,MNK45,BML 284
BML-284 HCL is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
价 格:¥电议型 号:T8820产 地:中国大陆
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T385435-(Biotinamido)pentylamine5(Biotinamido)pentylamine,5 (Biotinamido)pentylamine
5-(Biotinamido)pentylamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T38543产 地:中国大陆
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TN6742β-Damasconeβ Damascone,cancer,perfume,chemopreventive,inhibit,β-Damascone,volatile,mosquito,muscoid,
Damascone are a series of closely related chemical compounds that are components of a variety of essential oils. The damascones belong to a family of chemicals known as rose ketones, which also includes damascenones and ionones. beta-Damascone is a contributor to the aroma of roses, despite its relatively low concentration, and is an important fragrance chemical used in perfumery.
价 格:¥电议型 号:TN6742产 地:中国大陆
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T6603NelarabineHSB-2,Inhibitor,T-ALL,Nucleoside Antimetabolite/Analog,Apoptosis,acute lymphoblastic leuka
Nelarabine is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
价 格:¥电议型 号:T6603产 地:中国大陆
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T16475Pexacerfont
Pexacerfont is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).
价 格:¥电议型 号:T16475产 地:中国大陆
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T23801WCK-4234 sodiuminhibit,carbapenemases,antibacterial,KPC enzymes,diazabicyclooctanes (DBOs),Enterobac
WCK-4234 sodium is an inhibitor of β-lactamase can be used in studies targeting MDR infections. WCK-4234 sodium inhibits class A, C, and D β-lactamases and OXA carbapenemases.
价 格:¥电议型 号:T23801产 地:中国大陆
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T7611ODM-203anti-tumor immunity,ODM-203,FGFR,HUVEC,H1581,Inhibitor,cancer,Vascular endothelial growth fac
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
价 格:¥电议型 号:T7611产 地:中国大陆
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T6S0721Orientinneuroprotective,inhibit,Inhibitor,cardio,protection,Orientin
1. Orientin may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive defi
价 格:¥电议型 号:T6S0721产 地:中国大陆
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T0794Mepenzolate BromideHCAR2,PUMA-G,inhibit,Muscarinic acetylcholine receptor,Inhibitor,hM3R,gastrointes
Mepenzolate Bromide is a muscarinic antagonist used to treat gastrointestinal conditions.
价 格:¥电议型 号:T0794产 地:中国大陆
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T7144BTSfibers,muscle,Myosin,subfragment,inhibit,BTS,Inhibitor,skeletal,Ca2+,actin,ATPase
BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .
价 格:¥电议型 号:T7144产 地:中国大陆
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T9781Boc-C14-COOHADC Linkers,Antibody-drug conjugates linkers,Inhibitor,PROTAC Linkers,inhibit,Boc-C-14-C
Boc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T9781产 地:中国大陆
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TN6393fulvotomentoside Afulvotomentoside A
Fulvotomentoside A could decrease overexpression of IL-6 and IL-17A, and increase the expression of specific transcription factor Foxp3 of regulatory T cells significantly in intestine. It may be one of the mechanisms that Ful improved intestinal inflammation.
价 格:¥电议型 号:TN6393产 地:中国大陆
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T6798TretazicarTretazicar,NQO1,DNA Alkylator/Crosslinker,rat,bifunctional,Inhibitor,inhibit,agent,cross-l
CB1954(Tretazicar), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.
价 格:¥电议型 号:T6798产 地:中国大陆
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T15368LGalantide acetate
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide acetate dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide acetate appears to bind to a single population of SP receptors (KD~40 nM).
价 格:¥电议型 号:T15368L产 地:中国大陆
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T9697ASK1-IN-1CNS,inhibit,p38 MAPK,ASK1,ASK-1-IN-1,ASK1 IN 1,ASK1IN1,MAPK,Inhibitor,brain,penetrant
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.
价 格:¥电议型 号:T9697产 地:中国大陆