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T3794317-phenyl trinor Prostaglandin F2α isopropyl ester;17-phenyl trinor Prostaglandin F2α isopropyl este
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost. This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP r
价 格:¥电议型 号:T37943产 地:中国大陆
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T3793716-phenoxy tetranor Prostaglandin F2α methyl ester;16-phenoxy tetranor Prostaglandin F2α methyl este
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. 16-phenoxy tetranor PGF2α methyl ester is a lipophilic a
价 格:¥电议型 号:T37937产 地:中国大陆
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T3793616-phenoxy tetranor Prostaglandin F2α isopropyl ester;16-phenoxy tetranor Prostaglandin F2α isopropy
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
价 格:¥电议型 号:T37936产 地:中国大陆
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T37918Prostaglandin E2 isopropyl ester;Prostaglandin E2 isopropyl esterProstaglandin E2 isopropyl ester;Pr
Prostaglandin E2 (PGE2) isopropyl ester is a more lipophilic form of the free acid, PGE2. PG esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid by endogenous esterases upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of PGs show greatly diminished receptor activity in vitro compared to the parent free acids.
价 格:¥电议型 号:T37918产 地:中国大陆
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T37853Cholesteryl LignocerateCholesteryl LignocerateCholesteryl Lignocerate
Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum. Cholesteryl lignocerate can be hydrolyzed by cellular extracts from cultured human skin fibroblasts isolated from healthy individuals but not patients with cholesteryl ester storage disease (CESD) or Wolman disease.
价 格:¥电议型 号:T37853产 地:中国大陆
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T378362-hydroxy Tricosanoic Acid methyl ester;2-hydroxy Tricosanoic Acid methyl ester2-hydroxy Tricosanoic
2-hydroxy Tricosanoic Acid methyl ester can be used in related research in the field of life sciences. Its product number is T37836 and CAS number is 118745-41-8.
价 格:¥电议型 号:T37836产 地:中国大陆
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T37813Fluprostenol methyl ester;Fluprostenol methyl esterFluprostenol methyl ester
Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. The isopropyl ester of fluprostenol (travoprost) is an effective ocular hypotensive drug. CAY10532 is a methyl ester analog of fluprostenol.
价 格:¥电议型 号:T37813产 地:中国大陆
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T3779Crocin II;西红花苷IICrocin 2|||Crocetin gentiobiosylglucosyl ester|||Tricrocin|||Crocin B;Crocin 2|||西红花
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin II can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin II has antihyperlipidem
价 格:¥电议型 号:T3779产 地:中国大陆
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T376803-hydroxy Palmitic Acid methyl ester;3-hydroxy Palmitic Acid methyl ester3-hydroxy Palmitic Acid met
3-hydroxy Palmitic acid methyl ester (3-hydroxy PAME) is an esterized long-chain fatty acid involved in quorum sensing in R. solanacearum, a bacteria that causes lethal wilting in plants. 3-hydroxy-PAME (175 nM) increases levels of PhcA-regulated virulence factors, greater than 20-, 30-, and 25-fold for EPS I, EGL, and PME, respectively, in the AW1-83 strain of R. solanacearum.
价 格:¥电议型 号:T37680产 地:中国大陆
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T37620Leukotriene C4 methyl ester;Leukotriene C4 methyl esterLeukotriene C4 methyl ester
Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute all
价 格:¥电议型 号:T37620产 地:中国大陆
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T37616Leukotriene A4 methyl ester;Leukotriene A4 methyl esterLeukotriene A4 methyl ester;Leukotriene A4 me
Leukotriene A4 methyl ester can be converted into leukotriene C4 monomethyl ester catalyzed by the major alkaline cytosolic glutathione transferase in rat liver, which can be used in metabolism-related studies.
价 格:¥电议型 号:T37616产 地:中国大陆
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T37615Leukotriene A3 methyl ester;Leukotriene A3 methyl esterLeukotriene A3 methyl ester
Biosynthesis of LTA3 occurs from 5,8,11-eicosatrienoic acid via the 5-LO pathway and it is the putative intermediate in the biosynthesis of 3-series leukotrienes. LTA3 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.
价 格:¥电议型 号:T37615产 地:中国大陆
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T37482Diclofenac methyl ester;双氯酚甲酯Diclofenac methyl ester
Diclofenac methyl ester is a hydrophobic prodrug form of diclofenac which is a non-steroidal anti-inflammatory drug (NSAID). Diclofenac methyl ester is more soluble than diclofenac acid in isopropylmyristate but with higher toxicity.
价 格:¥电议型 号:T37482产 地:中国大陆
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T37481Diclofenac ethyl ester;Diclofenac ethyl esterDiclofenac ethyl ester
Diclofenac ethyl ester can be used in related research in the field of life sciences. Its product number is T37481 and CAS number is 15307-77-4.
价 格:¥电议型 号:T37481产 地:中国大陆
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T37473SBFI AM;SBFI AMSodium-binding Benzofuran Isophthalate Acetoxymethyl ester;Sodium-binding Benzofuran
SBFI AM is a membrane-permeant, fluorescent Na+ indicator dye. It is selective for Na+ over K+ with Kd values of 20 and 120 mM for these ions, respectively. [1]Increasing concentration of Na+ increases the ratio of excitation efficiency at 330-345 nm to that at 370-390 nm with emission collected at 450-550 nm. [1] Therefore, ratio fluorometry and imaging can be performed with the same wavelengths. SBF AM is suitable for single intracellular dye injection and is typically used for high-resolutio
价 格:¥电议型 号:T37473产 地:中国大陆
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T3739915(S)-HETE methyl ester;15(S)-HETE methyl ester15(S)-HETE methyl ester
15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE , a major arachidonic acid metabolite from the 15-lipoxygenase pathway. Methyl esters of lipids are commonly used in formulations of nutritional supplements.
价 格:¥电议型 号:T37399产 地:中国大陆
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T373195β-Dihydroprogesterone;5β-Dihydroprogesterone5β-Dihydroprogesterone
5β-Dihydroprogesterone (5β-DHP) is a progesterone receptor agonist and metabolite of progesterone .1,2It is formed from progesterone by 5β-reductase.25β-DHP inhibits spontaneous contractions in isolated rat uterus when used at a concentration of 10 μg/ml, an effect that can be blocked by the progesterone receptor antagonist RU486 but not the GABAAreceptor antagonist picrotoxin .1It is a negative modulator of homooligomeric Ρ1 subunit-containing GABAAreceptors, inhibiting GABA-induced currents in
价 格:¥电议型 号:T37319产 地:中国大陆
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T373045-OxoETE methyl ester;5-OxoETE methyl ester5-OxoETE methyl ester
5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE . 5-OxoETE methyl ester is an agonist of oxoeicosanoid receptor 1 (OXER1; EC50 = 1.54 μM for β-arrestin recruitment) that has a higher maximal response than 5-oxoETE in a β-arrestin assay.
价 格:¥电议型 号:T37304产 地:中国大陆
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T3730Methyl gallate;没食子酸甲酯NSC 363001|||Gallicin|||Gallic acid methyl ester|||Gallincin;NSC 363001|||Galli
Methyl gallate (Gallincin) is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
价 格:¥电议型 号:T3730产 地:中国大陆
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T37290Resolvin D3 methyl ester;Resolvin D3 methyl esterResolvin D3 methyl ester
Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
价 格:¥电议型 号:T37290产 地:中国大陆