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T36545Prostaglandin D2 methyl ester;Prostaglandin D2 methyl esterProstaglandin D2 methyl ester;Prostagland
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation. Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2. It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.
价 格:¥电议型 号:T36545产 地:中国大陆
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T36440GS-441524 tris-isobutyryl ester;GS-441524 tris-isobutyryl esterGS-441524 tris-isobutyryl ester
GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with an EC50value of 0.26 μM.
价 格:¥电议型 号:T36440产 地:中国大陆
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T36241Arecaidine propargyl ester (hydrobromide)Arecaidine propargyl ester (hydrobromide)Arecaidine proparg
Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 μM, respectively). Arecaidine propargyl ester induces contractions in isolated guinea pig atrium (pD2= 8.67). It induces apoptosis and the production of reactive oxygen species (ROS) in U87 and U251 glioblastoma cells when used at a concentration of 100 μM.2Arecai
价 格:¥电议型 号:T36241产 地:中国大陆
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T3621719-hydroxy Cholesterol;19-hydroxy Cholesterol19-hydroxy Cholesterol
19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. It has been used as an internal standard for the quantitative determination of sterols by mass spectroscopic analysis.[1]
价 格:¥电议型 号:T36217产 地:中国大陆
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T36198Avenanthramide-C methyl esterAvenanthramide-C methyl esterAvenanthramide C methyl ester|||Avenanthra
Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.
价 格:¥电议型 号:T36198产 地:中国大陆
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T361618-iso Prostaglandin E2 isopropyl ester;8-iso Prostaglandin E2 isopropyl ester8-iso Prostaglandin E2
8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.
价 格:¥电议型 号:T36161产 地:中国大陆
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T3615615(S)-15-methyl Prostaglandin F2α methyl ester;15(S)-15-methyl Prostaglandin F2α methyl ester15(S)-1
15(S)-15-methyl Prostaglandin F2α methyl ester can be used in related research in the field of life sciences. Its product number is T36156 and CAS number is 35700-21-1.
价 格:¥电议型 号:T36156产 地:中国大陆
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T3615515(S)-15-methyl Prostaglandin F2α isopropyl ester;15(S)-15-methyl Prostaglandin F2α isopropyl ester1
15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor. 15(S)-15-methyl PGF2α isopropyl ester is a lipophilic analog of 15(S)-15-methyl PGF2α methyl ester, which may be hydrolyzed in vivo to the fully active free acid.
价 格:¥电议型 号:T36155产 地:中国大陆
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T361203-hydroxy Tridecanoic Acid methyl ester;3-hydroxy Tridecanoic Acid methyl ester3-hydroxy Tridecanoic
3-hydroxy Tridecanoic acid methyl ester is a hydroxylated fatty acid methyl ester and major fatty acid component of A. lipolytica and A. glycerini. It has been used in the synthesis of components of the female sex pheromone of the painted apple moth (T. anartoides).
价 格:¥电议型 号:T36120产 地:中国大陆
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T36052Lipoxin A4 methyl ester;Lipoxin A4 methyl esterLXA4 methyl ester;LXA4 methyl ester
Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 μM.[2] LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural
价 格:¥电议型 号:T36052产 地:中国大陆
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T36018Phosphodiesterase 4 Inhibitor;Phosphodiesterase 4 InhibitorPhosphodiesterase 4 Inhibitor
Phosphodiesterase 4 (PDE4) inhibitor is an inhibitor of PDE4 with an IC50 value of 0.10 μM for the human recombinant enzyme.
价 格:¥电议型 号:T36018产 地:中国大陆
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T359776α-hydroxy Cholesterol;6α-hydroxy Cholesterol6α-hydroxy Cholesterol|||6α-OHC;6α-hydroxy Cholesterol|
6α-hydroxy Cholesterol is an oxysterol that increases superoxide anion production in SK-N-BE cells when used at concentrations of 50 and 100 μM.
价 格:¥电议型 号:T35977产 地:中国大陆
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T35973Cholesterol-5α,6α-epoxide;胆固醇-5Α,6Α-环氧化物Epoxycholesterol|||5α,6α-epoxy Cholestanol|||NSC 18176;Epoxy
Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE application.
价 格:¥电议型 号:T35973产 地:中国大陆
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T35941DC-Chol hydrochloride;DC-胆固醇盐酸盐?Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride|||DC-Ch
DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited amyloid formation from oxidized hCT in a dose-dependent manner.DC-Chol hydrochloride induces an improved and balanced immunity, which could contribute to hepatitis B vaccine research.
价 格:¥电议型 号:T35941产 地:中国大陆
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T358539(S)-HODE cholesteryl ester;9(S)-HODE cholesteryl ester9(S)-HODE cholesteryl ester
9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 9(S)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
价 格:¥电议型 号:T35853产 地:中国大陆
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T3584613(R)-HODE cholesteryl ester;13(R)-HODE cholesteryl ester13(R)-HODE cholesteryl ester
13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 13(R)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
价 格:¥电议型 号:T35846产 地:中国大陆
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T358439(R)-HODE cholesteryl ester;9(R)-HODE cholesteryl ester9(R)-HODE cholesteryl ester
9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 9(R)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
价 格:¥电议型 号:T35843产 地:中国大陆
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T357032-hydroxy Stearic Acid methyl ester;2-hydroxy Stearic Acid methyl ester2-hydroxy Stearic Acid methyl
2-hydroxy Stearic acid is a hydroxylated fatty acid methyl ester that broadens phase transition in dimyristoylphosphatidylcholine (DMPC) lipid membranes. It has been used in the synthesis of lipid-nucleotide conjugate anti-HIV agents to increase phosphodiester bond cleavage and the amount of liberated intracellular nucleotides.
价 格:¥电议型 号:T35703产 地:中国大陆
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T356772,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester;2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester2,3,4
2,3,4-Tri-O-acetyl-β-D-glucuronide methyl ester is a synthetic intermediate in the synthesis of prodrug forms of the antitumor antibiotic daunomycin .1
价 格:¥电议型 号:T35677产 地:中国大陆
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T35633Pinolenic Acid ethyl ester;Pinolenic Acid ethyl esterPinolenic Acid ethyl ester
Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils. Both oils have been found to have lipid-lowering properties. A diet containing maritime pine seed oil (MPSO) lowered high-density lipoprotein and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux in vitro. Korean pine seed oil supplements may help in obesity by reduction of appetite. People taking this oil had an
价 格:¥电议型 号:T35633产 地:中国大陆