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T11335Fulvestrant (S enantiomer);化合物 T11335ZM 182780 S enantiomer|||ICI 182780 S enantiomer|||Fulvestrant
Fulvestrant S enantiomer is the less active S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
价 格:¥电议型 号:T11335产 地:中国大陆
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T11334Fulvestrant (R enantiomer);化合物 T11334ICI 182780 R enantiomer|||ZD 9238 R enantiomer|||ZM 182780 R en
Fulvestrant R enantiomer is the less active R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
价 格:¥电议型 号:T11334产 地:中国大陆
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T11304Fluphenazine enanthate;化合物 T11304Fluphenazine enanthate
Fluphenazine enanthate is a novel long-acting injectable (LAI) antipsychotic compound specifically designed for the treatment of schizophrenia.
价 格:¥电议型 号:T11304产 地:中国大陆
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T1127Beclometasone dipropionate二丙酸倍氯米松Beclovent|||Beclomethasone dipropionate|||二丙酸倍氯米松|||丙酸倍氯米松|||Becona
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.
价 格:¥电议型 号:T1127产 地:中国大陆
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T11262Falintolol, (Z)-;化合物 T11262Falintolol, (Z)-
Falintolol, (Z)-, is a novel β-adrenergic antagonist compound distinguished by the inclusion of an oxime moiety.
价 格:¥电议型 号:T11262产 地:中国大陆
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T11237LCamizestrant TFA;Camizestrant三氟乙酸盐Camizestrant TFA(2222844-89-3 Free base)|||AZD-9833 TFA;Camizestra
Camizestrant TFA (AZD-9833 TFA) is a potent and orally active antagonist of estrogen receptor (ER).
价 格:¥电议型 号:T11237L产 地:中国大陆
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T11237Camizestrant;化合物CamizestrantEstrogen receptor antagonist 2;Estrogen receptor antagonist 2
Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].
价 格:¥电议型 号:T11237产 地:中国大陆
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T11236Giredestrant tartrate;Giredestrant酒石酸盐Estrogen receptor antagonist 1;Estrogen receptor antagonist 1
Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure of ER to activate the transcription of targeted genes and promoting the degradation of ER protein. Giredestrant tartrate can be used to treat tumor diseases.
价 格:¥电议型 号:T11236产 地:中国大陆
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T11230ERRα antagonist-1;化合物ERRα 拮抗剂-1ERR+/- antagonist-1|||ERRa antagonist-1;ERR+/- antagonist-1|||ERRa an
ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, displaying IC50 values of 170 nM and 180 nM, respectively. Notably, ERRα antagonist-1 does not interfere with the interactions involving ERRβ or ERRγ and the PGC-1α and PGC-1β coactivators. Furthermore, it does not affect the interaction between ei
价 格:¥电议型 号:T11230产 地:中国大陆
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T11211EP4 receptor antagonist 1;化合物EP4 receptor antagonist 1EP4 receptor antagonist 1
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and 16.2 nM, respectively, while displaying minimal activity (IC50s >10 μM) against human EP1, EP2, and EP3 receptors.
价 格:¥电议型 号:T11211产 地:中国大陆
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T11207Entacapone sodium salt;恩他卡朋钠盐Entacapone sodium salt
Entacapone sodium salt inhibits catechol-O-methyltransferase(COMT) with similar IC50 in different tissues including live, duodenum, kidney and lung, but entacapone is more active than tolcapone in those tissues. Entacapone (< 100 μM) is a potent inhibitor of α-syn and β-amyloid (Aβ) oligomerization and fibrillogenesis, and also protects against extracellular toxicity induced by the aggregation of both proteins in PC12 cells.Entacapone sodium salt is a specific, potent, peripherally acting catech
价 格:¥电议型 号:T11207产 地:中国大陆
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T11206ent-Tadalafil;化合物 T11206ent-IC-351;ent-IC-351
ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).
价 格:¥电议型 号:T11206产 地:中国大陆
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T11205ent-Ezetimibe;ENT-依折麦布ent-SCH 58235;ent-SCH 58235|||ENT-依折麦布
Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.ent-Ezetimibe (ent-SCH 58235) (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor.?
价 格:¥电议型 号:T11205产 地:中国大陆
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T11195Enantiomer of Sofosbuvir;化合物 T11195Enantiomer of Sofosbuvir
Sofosbuvir´s enantiomer, a variant of the prescription medication Sofosbuvir used for chronic hepatitis C treatment, currently lacks reported biological activity.
价 格:¥电议型 号:T11195产 地:中国大陆
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T11189Emtricitabine S-oxide;化合物 T11189Emtricitabine Degradant-III|||Emtricitabine sulfoxide;Emtricitabine
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine.
价 格:¥电议型 号:T11189产 地:中国大陆
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T11173LElacestrant S enantiomer dihydrochloride;化合物 T11173LRAD1901 S enantiomer dihydrochloride|||RAD-1901
Elacestrant (RAD1901) dihydrochloride is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant S enantiomer dihydrochloride is an low activity enantiomer of elacestrant dihydrochloride.
价 格:¥电议型 号:T11173L产 地:中国大陆
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T11173Elacestrant S enantiomer;化合物 T11173RAD1901 S enantiomer;RAD1901 S enantiomer
Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively.
价 格:¥电议型 号:T11173产 地:中国大陆
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T11164EGFR mutant-IN-1;化合物 T11164EGFR mutant-IN-1
EGFR mutant- in-1, A 5-methylpyrimidopyridone derivative are effective selective EGFRL858R/T790M/C797S mutant inhibitors with IC50 of 27.5 nM, which significantly weakened EGFRWT effect.
价 格:¥电议型 号:T11164产 地:中国大陆
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T11156Nazartinib S-enantiomer;化合物 T11156EGF816 (S-enantiomer);EGF816 (S-enantiomer)
Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.
价 格:¥电议型 号:T11156产 地:中国大陆
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T11137(E)-GABAB receptor antagonist 1;(E)-GABAB受体拮抗剂-1(E)-GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格:¥电议型 号:T11137产 地:中国大陆