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T76889Prasinezumab;化合物 PrasinezumabPrasinezumab
Prasinezumab (PRX 002), a humanized IgG1 monoclonal antibody targeting aggregated α-synuclein, shows promise for Parkinson´s disease research [1].
价 格:¥电议型 号:T76889产 地:中国大陆
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T76888Quetmolimab;奎莫利单抗E-6011|||KANAb 001;E-6011|||KANAb 001
Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis.
价 格:¥电议型 号:T76888产 地:中国大陆
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T76887Rinucumab;化合物 RinucumabRinucumab
Rinucumab (REGN 2176), a monoclonal antibody that acts as a PDGF inhibitor, holds potential for researching neovascular age-related macular degeneration [1].
价 格:¥电议型 号:T76887产 地:中国大陆
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T76886Semorinemab;化合物 SemorinemabSemorinemab
Semorinemab (RG 6100), an anti-Tau humanized IgG4 monoclonal antibody, selectively targets the N-terminal portion of the Tau protein, specifically amino acid residues 6-23. It exhibits a binding affinity to human Tau with a dissociation constant (Kd) of 3.8 nM. This compound is utilized in Alzheimer´s Disease research [1].
价 格:¥电议型 号:T76886产 地:中国大陆
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T76885Sonelokimab;化合物 SonelokimabSonelokimab
Sonelokimab (ALX 0761; M 1095) is a trivalent nanobody that combines monovalent camelid-derived nanobodies targeting human interleukin (IL)-17A and IL-17F, along with human serum albumin VHHs. This composition presents sonelokimab as a promising candidate for the investigation of plaque-type psoriasis treatments [1] [2].
价 格:¥电议型 号:T76885产 地:中国大陆
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T76884Spesolimab;司柏索利单抗BI 655130;BI 655130
Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. IL-36 plays an important role in the immune system and is associated with a reduction in biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.
价 格:¥电议型 号:T76884产 地:中国大陆
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T76883Talacotuzumab;塔妥珠单抗CSL 362|||JNJ 56022473;CSL 362|||JNJ 56022473
Talacotuzumab (JNJ 56022473) is an IgG1 fully humanized CD123 neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has a high affinity for CD123, CD32b/c, CD16-158F and CD16-158V, with KD of 0.43 nM, 188 nM, 46 nM and 16.8 nM, respectively. Talacotuzumab inhibits IL-3 signaling in target cells by inhibiting IL-3 binding to CD123. Talacotuzumab induces mutations in the Fc region to increase affinity for CD16 (FCγriiia), thereby enhancing antibody-dependent cell-media
价 格:¥电议型 号:T76883产 地:中国大陆
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T76882Talquetamab;塔奎妥单抗JNJ-64407564|||JNJ-7564;JNJ-64407564|||JNJ-7564
Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody for multiple myeloma with antitumor activity that induces T-cell-mediated killing of GPRC5-expressing MM cells through T-cell recruitment and activation.Talquetamab is used to treat multiple myeloma (MM).
价 格:¥电议型 号:T76882产 地:中国大陆
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T76881Teclistamab;化合物 TeclistamabTeclistamab
Teclistamab, a human bispecific antibody targeting both BCMA on target cells and CD3 on T cells, facilitates T cell-mediated cytotoxicity, which results in T cell activation and subsequent target cell lysis. This compound has applications in research studies concerning multiple myeloma (MM) [1].
价 格:¥电议型 号:T76881产 地:中国大陆
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T76880Tepoditamab;化合物 TepoditamabTepoditamab
Tepoditamab (MCLA-117) is a bispecific monoclonal antibody designed to target CLEC12A on myeloid cells and CD3 on cytotoxic T cells. CLEC12A serves as a myeloid differentiation antigen. The compound effectively eliminates AML leukemia progenitor and stem cells by inducing T cell-mediated proliferative lysis, making it a valuable asset in acute myeloid leukemia (AML) research [1].
价 格:¥电议型 号:T76880产 地:中国大陆
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T76879Vesencumab;化合物 VesencumabVesencumab
Vesencumab (MNRP-1685A), an IG1 antibody targeting neuropilin-1 (NRP-1), inhibits the interaction between NRP-1 and VEGFR-2. This action confers anti-angiogenic and anti-neoplastic properties to Vesencumab. It is utilized in studying metastatic solid tumors, notably ovarian cancer [1] [2].
价 格:¥电议型 号:T76879产 地:中国大陆
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T76878Vobarilizumab;化合物 VobarilizumabVobarilizumab
Vobarilizumab (ALX-0061) is a monoclonal antibody (mAb) targeting the IL-6 receptor (IL-6R) with a dissociation constant (Kd) of 0.19 pM, indicating high affinity for its target. This compound features both an anti-IL-6R domain and an anti-human serum albumin domain, making it a potential research tool for investigating inflammatory autoimmune diseases like rheumatoid arthritis [1] [2] [3].
价 格:¥电议型 号:T76878产 地:中国大陆
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T76877Vofatamab;沃凡妥单抗RG-7444|||B-701|||MFGR-1877S;RG-7444|||B-701|||MFGR-1877S
Vofatamab (B-701) is a fully human monoclonal antibody targeting FGFR3. Vofatamab has potential anticancer and antitumor activity and is often used in combination with other compounds to treat cancer.
价 格:¥电议型 号:T76877产 地:中国大陆
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T76876Volagidemab;化合物 VolagidemabVolagidemab
Volagidemab, a monoclonal antibody (mAb) that antagonizes the glucagon receptor (GCGR), is utilized in researching Type 1 Diabetes (T1D) [1] [2].
价 格:¥电议型 号:T76876产 地:中国大陆
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T76875Zanidatamab;化合物 ZanidatamabZanidatamab
Zanidatamab (ZW25) is a bispecific, humanized monoclonal antibody that targets two distinct epitopes (ECD2 and ECD4) of the HER2 receptor, exhibiting anti-tumor activity [1].
价 格:¥电议型 号:T76875产 地:中国大陆
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T76874Erenumab;厄瑞努单抗AMG-334;AMG-334
Erenumab is a whole-human monoclonal antibody. Erenumab inhibits calcitonin gene-related peptide (CGRP) receptors. Erenumab can be used to prevent migraine attacks.
价 格:¥电议型 号:T76874产 地:中国大陆
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T76873Nidanilimab尼达利单抗CAN04
Nidanilimab (CAN04) is a fully humanized IL1RAP monoclonal antibody with a Kd value of 1.10 pM. Nidanilimab has antitumor activity, cutting off the IL1α and IL1β signaling pathways and inducing the immune system to destroy tumor cells. Nidanilimab can be used to study solid cancers such as non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC).
价 格:¥电议型 号:T76873产 地:中国大陆
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T76872Neihulizumab;化合物 NeihulizumabNeihulizumab
Neihulizumab (ALTB-168), an immune checkpoint agonistic antibody, targets and binds to human CD162 (PSGL-1), resulting in the downregulation of activated T-cells. It is utilized in research aimed at treating steroid-refractory acute graft-versus-host disease (SR-aGVHD), psoriasis, psoriatic arthritis, and ulcerative colitis [1].
价 格:¥电议型 号:T76872产 地:中国大陆
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T76871Navicixizumab;化合物 NavicixizumabNavicixizumab
Navicixizumab (OMP-305B83) is a bispecific anti- VEGF and anti- DLL4 inhibitory antibody. Navicixizumab can combine with Paclitaxel for cancer research. Navicixizumab can be used in the research of ovarian, primary peritoneal, or fallopian tube cancer [1] [2] [3] .
价 格:¥电议型 号:T76871产 地:中国大陆
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T76870Narsoplimab纳索利单抗OMS 721
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway activation. It can inhibit the agglutinin pathway. Narsoplimab can be used to study diseases associated with hematopoietic stem cell transplantation in adults.
价 格:¥电议型 号:T76870产 地:中国大陆