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T14871Carboxyamidotriazole Orotate；化合物Carboxyamidotriazole OrotateL-651582 Orotate|||CAI Orotate；L-651582
Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor that in vitro has been shown to possess antileukaemic activities. Carboxyamidotriazole Orotate shows anti-tumor, anti-inflammatory, and antiangiogenic effects.
价 格：￥电议型 号：T14871产 地：中国大陆
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T14815Bromo-PEG8-Boc；化合物 T14815Bromo-PEG8-Boc
Bromo-PEG8-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14815产 地：中国大陆
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T14766BPH-715；化合物BPH-715BPH-715
BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.
价 格：￥电议型 号：T14766产 地：中国大陆
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T14715Boc-Aminooxy-PEG3-C2-NH2；化合物 T14715Boc-Aminooxy-PEG3-C2-NH2
Boc-Aminooxy-PEG3-C2-NH2 is a polyethylene glycol (PEG) derived linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T14715产 地：中国大陆
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T14685BMS-986158；化合物BMS-986158BMS-986158
BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple negative breast cancer (TNBC) cells.
价 格：￥电议型 号：T14685产 地：中国大陆
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T14615Biphenylindanone A；化合物 T14615BINA；BINA
Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.
价 格：￥电议型 号：T14615产 地：中国大陆
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T14546Bermoprofen；柏莫洛芬AD-1590|||AJ-1590；AD-1590|||AJ-1590
Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.
价 格：￥电议型 号：T14546产 地：中国大陆
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T14515BCL6-IN-8c；化合物 T14515BCL6-IN-8c
BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbent assay).
价 格：￥电议型 号：T14515产 地：中国大陆
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T14497BAM 15；化合物BAM 15BAM 15
BAM 15 is an uncoupler of mitochondrial protonophore.
价 格：￥电议型 号：T14497产 地：中国大陆
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T14415Azido-PEG11-amine；化合物 T14415Azido-PEG11-amine
Azido-PEG11-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14415产 地：中国大陆
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T14371Barasertib；巴拉塞替AZD1152；巴拉塞替|||AZD1152
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
价 格：￥电议型 号：T14371产 地：中国大陆
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T14360AX-15836；化合物AX-15836AX-15836
AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).
价 格：￥电议型 号：T14360产 地：中国大陆
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T1433Ritodrine hydrochloride；盐酸利托君DU21220|||Ritodrine HCl|||NSC 291565；DU21220|||盐酸利托君|||Ritodrine HCl|||
Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vasc
价 格：￥电议型 号：T1433产 地：中国大陆
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T14320ARL67156 trisodium salt；化合物 T14320ARL67156 trisodium salt
ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.
价 格：￥电议型 号：T14320产 地：中国大陆
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T14316AR-C155858；化合物AR-C155858AR-C155858
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
价 格：￥电议型 号：T14316产 地：中国大陆
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T14315AR-9281；化合物AR-9281APAU；APAU
AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes
价 格：￥电议型 号：T14315产 地：中国大陆
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T14303Alrizomadlin；化合物AlrizomadlinAPG-115|||AA-115；APG-115|||AA-115
Alrizomadlin (APG-115) is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.
价 格：￥电议型 号：T14303产 地：中国大陆
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T1425Pemirolast potassium；吡嘧司特钾BMY 26517|||TWT-8152；BMY 26517|||TWT-8152|||吡嘧司特钾
Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium (TWT-8152) exerts its action by blocking the antigen-mediated calcium ion influx into mast cells.
价 格：￥电议型 号：T1425产 地：中国大陆
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T14238Amino-PEG4-Boc15-氨基-4,7,10,13-四氧杂十五烷酸叔丁酯15-氨基-4,7,10,13-四氧杂十五烷酸叔丁酯
Amino-PEG4-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
价 格：￥电议型 号：T14238产 地：中国大陆
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T14215AMG 837 sodium salt；化合物 T14215AMG 837 sodium salt
AMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agonist AMG 837 displayed the expected two-fold increase in potency on GPR4 (EC50 = 13 [±7] nM) compared to the racemic compound and its activity crossed over to the rat and mouse forms of GPR40 (EC50 = 23 and 13 nM, respectively). AMG 837 is a highly potent stimulator of insulin secr
价 格：￥电议型 号：T14215产 地：中国大陆
