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T28631RX821002；化合物 T28631RX-821002|||RX 821002；RX-821002|||RX 821002
RX821002 is a potent and selective antagonist of α2-adrenoceptor with low affinity for imidazoline sites. RX821002 displays selectivity for the α2D over the α2A subtypes (pKd values are 9.7 and 8.2 respectively).
价 格：￥电议型 号：T28631产 地：中国大陆
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T28617RS 100329；化合物 T28617RS100329 HCl|||RS 100329 HCl|||RS100329|||RS-100329；RS100329 HCl|||RS 100329 HCl
RS 100329 HCl is a selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors).
价 格：￥电议型 号：T28617产 地：中国大陆
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T28442PPL-100；化合物 T28442PL 461|||PL461|||PL-461|||PPL100；PL 461|||PL461|||PL-461|||PPL100
PPL-100, a HIV protease inhibitor, is used potentially for the treatment of HIV infection.
价 格：￥电议型 号：T28442产 地：中国大陆
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T28374PF-06651481-00；化合物PF-06651481-00PF0665148100|||PF 06651481 00|||Bosutinib Isomer I；PF0665148100|||PF
PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.
价 格：￥电议型 号：T28374产 地：中国大陆
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T28359PF 10040；化合物 T28359PF-10040|||PF10040；PF-10040|||PF10040
PF 10040 is an antagonist of platelet activating factor (PAF).
价 格：￥电议型 号：T28359产 地：中国大陆
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T28269ORY-1001 free base；化合物 T28269RG 6016|||ORY-1001|||ORY 1001|||ORY1001|||RG-6016|||RG6016；RG 6016|||OR
ORY-1001 is a KDM1A inhibitor (IC50 <20nM) with high selectivity against related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B >100uM, SMOX 7uM). Treatment of THP-1 (MLL-AF9) cells with ORY-1001, results in a time/dose dependent me2H3K4 accumulation at KDM1A target genes and concomitant induction of differentiation markers (EC50 me2H3K4 and FACS CD11b <1nM). ORY-1001 induces apoptosis in THP-1 and inhibits proliferation and colony formation of MV(4;11) (MLL-AF4) cells (EC50 <1nM). ORY-1001 d
价 格：￥电议型 号：T28269产 地：中国大陆
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T28237Onapristone；化合物 T28237IVV-1001|||ZK 98299|||IVV 1001|||ZK98299|||ZK-98299|||IVV1001；IVV-1001|||ZK 98
Onapristone, a progesterone receptor antagonist, is used potentially for the treatment of breast cancer, advanced prostate cancer, and inducer of vaginal bleeding.
价 格：￥电议型 号：T28237产 地：中国大陆
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T28179NMK-TD-100；化合物 T28179NMK-TD 100|||NMK-TD100；NMK-TD 100|||NMK-TD100
NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin. Polymerization of tissue purified tubulin into microtubules was inhibited by NMK-TD-100 with an IC50 value of 17.5±0.35 ?M.
价 格：￥电议型 号：T28179产 地：中国大陆
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T28100MRS2298；化合物 T28100MRS-2298|||MRS 2298；MRS-2298|||MRS 2298
MRS2298, a potent antagonists of the P2Y 1 receptor, has antiaggregatory activity in human platelets.
价 格：￥电议型 号：T28100产 地：中国大陆
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T28017Merbarone化合物 T28017RLBN-1001|||NSC-336628|||RLBN1001|||NSC336628
Merbarone is a Type II DNA topoisomerase inhibitor. Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage. Merbarone induces activation of caspase-activated DNase and excision of chromosomal DNA loops from the nuclear matrix. Merbarone induces apoptosis in CEM cells through activation of ICE/CED-3-like protease.
价 格：￥电议型 号：T28017产 地：中国大陆
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T28013(Rac)-MEM 1003；化合物 T28013MEM1003|||BAY-Z-4406|||BAY-Z4406|||BAY Z-4406|||MEM-1003|||MEM 1003；MEM1003
MEM-1003, a calcium channel blocker, is used potentially for the treatment of bipolar disorders.
价 格：￥电议型 号：T28013产 地：中国大陆
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T28005MDL-100240；化合物 T28005MDL-100240
MDL-100240 is a dual inhibitor of angiotensin-converting enzyme (ACE) and neprilysin with a balanced activity. MDL 100240 shows an impressive effectiveness both in preventing and in regressing hypertension-induced vascular remodeling and cardiac hypertrophy.
价 格：￥电议型 号：T28005产 地：中国大陆
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T27966M1000907；化合物 T27966M-1000907|||M 1000907；M-1000907|||M 1000907
M1000907 is a selective 5-HT2A receptor antagonist. It may interfere with altered 5-HT2A receptor signaling that contributes to ASD symptoms.
价 格：￥电议型 号：T27966产 地：中国大陆
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T27795L(Iso)-Landipirdine；异构体兰地匹定(Iso)-SYN120|||(Iso)-RO5025181|||(Iso)-Landipirdine(Iso-1000308-25-7)；(Iso
(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist. (Iso)-Landipirdine has a significant effect on the hERG pharmacophore and can be used to study neurological disorders in the Alzheimer´s disease class.
价 格：￥电议型 号：T27795L产 地：中国大陆
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T27739KR-31378；化合物 T27739MSH1001|||DNB 001|||DNB-001|||DNB001|||MSH-1001|||KR31378；MSH1001|||DNB 001|||DNB
KR-31378, a K(ATP) channel activator, is used potentially for the treatment of ocular hypertension and glaucoma.
价 格：￥电议型 号：T27739产 地：中国大陆
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T27525HA-1004；化合物HA-1004HA-1004
HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.
价 格：￥电议型 号：T27525产 地：中国大陆
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T27445GSK-1004723；化合物 T27445GSK 1004723；GSK 1004723
GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.
价 格：￥电议型 号：T27445产 地：中国大陆
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T27413Trimebutine CTB salt；曲美布汀 CTB 盐GIC1001；GIC1001
Trimebutine CTB salt (GIC-1001) is an opioid receptor agonist used in the study of pain.
价 格：￥电议型 号：T27413产 地：中国大陆
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T27223DW10075；化合物 T27223DW-10075|||DW 10075；DW-10075|||DW 10075
DW10075, a novel potent and highly selective inhibitor of VEGFR, exhibits antitumor activities both in vitro and in vivo.
价 格：￥电议型 号：T27223产 地：中国大陆
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T27100CUMI-101；化合物 T27100CUMI-101
CUMI-101 is an agonist of 5-HT1A receptor.
价 格：￥电议型 号：T27100产 地：中国大陆
