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T60031NRX-1933inhibit,NRX-1933,NRX1933,Inhibitor,NRX 1933
NRX-1933 is a molecular glue and enhances the interaction between an oncogenic transcription factor, β-Catenin, and its cognate E3 ligase, SCFβ-TrCP.
价 格:¥电议型 号:T60031产 地:中国大陆
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TP1937L1RFRP-1 (human) acetate(311309-25-8 free base)RFRP1 (human) acetate(311309258 free base),RFRP 1 (huma
RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog.
价 格:¥电议型 号:TP1937L1产 地:中国大陆
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T19337GBR 12783 dihydrochloride
GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.
价 格:¥电议型 号:T19337产 地:中国大陆
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T6518GossypolInhibitor,BL-193,BL193,Gossypol,Bcl-2 Family,inhibit
Gossypol Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
价 格:¥电议型 号:T6518产 地:中国大陆
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T7193Enceniclineinhibit,nAChR,Encenicline,EVP 6124,Nicotinic acetylcholine receptors,EVP6124,Inhibitor
Encenicline is a selective α7 nicotinic acetylcholine receptor (nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer´s disease.
价 格:¥电议型 号:T7193产 地:中国大陆
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TP1933R715 TFA(185052-09-9 free base)R715 TFA(185052 09 9 free base),R715 TFA(185052099 free base),R-715 T
Potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable.
价 格:¥电议型 号:TP1933产 地:中国大陆
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TP1936L1RFRP3(human) acetate(311309-27-0 free base)RFRP-3(human) acetate(311309-27-0 free base),RFRP3(human)
RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM.
价 格:¥电议型 号:TP1936L1产 地:中国大陆
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T9025KY19382Glycogen synthase kinase 3,Beta catenin,β-catenin,GSK-3,KY 19382,inhibit,Wnt,Inhibitor,KY-193
KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of 19 and 10 nM, respectively). It activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.
价 格:¥电议型 号:T9025产 地:中国大陆
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TP1939L1RVD-Hpα acetate(1193362-76-3 free base)RVD Hpα acetate(1193362 76 3 free base),RVDHpα acetate(119336
RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist. Increases intracellular Ca2+ levels in cells expressing CB1 receptors in vitro. Also high affinity CB2 positive allosteric modulator (Ki = 50 nM).
价 格:¥电议型 号:TP1939L1产 地:中国大陆
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T13193TPN171TPN-171,TPN171
TPN171 is a selective and oral bioavailable phosphodiesterase type 5 (PDE5) inhibitor (IC50: 0.62 nM), which has the potential for the treatment of pulmonary arterial hypertension (PAH).
价 格:¥电议型 号:T13193产 地:中国大陆
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TP1930L1Spexin acetate(1370290-58-6 free base)Spexin acetate(1370290586 free base),Spexin acetate(1370290 58
Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.
价 格:¥电议型 号:TP1930L1产 地:中国大陆
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T21855AMI-193
AMI-193 is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 Receptor, and 5-HT1C Receptor. AMI-193 shows antipsychotic activity.
价 格:¥电议型 号:T21855产 地:中国大陆
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T30544BMS-919373
BMS-919373 is a potassium channel Kv1.5 (KCNA5) inhibitor for atrial fibrillation and acute coronary syndrome.
价 格:¥电议型 号:T30544产 地:中国大陆
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TN71932,4,6-Triphenylaniline
2,4,6-Triphenylaniline is a marine derived natural products found in Alternaria longipes.
价 格:¥电议型 号:TN7193产 地:中国大陆
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TP1932L1[D-Trp7,9,10]-Substance P acetate[DTrp7,9,10]Substance P acetate,[D Trp7,9,10] Substance P acetate
[D-Trp7,9,10]-Substance P acetate is an analogue of substance P which inhibits ion conductance through nicotinic acetylcholine receptors.
价 格:¥电议型 号:TP1932L1产 地:中国大陆
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T6158LDN-193189 HClLDN193189 Hydrochloride
LDN193189 hydrochloride is a selective BMP type I receptor kinases inhibitor.
价 格:¥电议型 号:T6158产 地:中国大陆
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T6131PimasertibN-[(2S)-2,3-二羟基丙基]-3-[(2-氟-4-碘苯基)氨基]-4-吡啶甲酰胺;MSC1936369B;AS703026;SAR 245509
Pimasertib is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
价 格:¥电议型 号:T6131产 地:中国大陆
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T6087AZD 6482KIN 193;AZD6482
AZD 6482 is a potent and selective p110β inhibitor with IC50 of 0.69 nM and a PI3Kβ inhibitor with IC50 of 10 nM.
价 格:¥电议型 号:T6087产 地:中国大陆
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T5640GSK2193874
GSK2193874 was identified as a selective, orally active TRPV4 blocker.
价 格:¥电议型 号:T5640产 地:中国大陆
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T5193DanirixinGSK1325756
Danirixin is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).
价 格:¥电议型 号:T5193产 地:中国大陆