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T1943ML347ML347,LDN 193719,
ML347(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.
价 格:¥电议型 号:T1943产 地:美洲
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T21932-Chloropyrazine2-Chloropyrazine
2-Chloropyrazine is used in chemical industry.
价 格:¥电议型 号:T2193产 地:美洲
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T5193DanirixinDanirixin,GSK1325756,
Danirixin is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).
价 格:¥电议型 号:T5193产 地:美洲
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T5640GSK2193874GSK2193874
GSK2193874 was identified as a selective, orally active TRPV4 blocker.
价 格:¥电议型 号:T5640产 地:美洲
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T6087AZD6482AZD6482,KIN 193,
AZD 6482 is a potent and selective p110β inhibitor with IC50 of 0.69 nM and a PI3Kβ inhibitor with IC50 of 10 nM.
价 格:¥电议型 号:T6087产 地:美洲
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T6131PimasertibPimasertib,MSC1936369B,AS703026
Pimasertib is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
价 格:¥电议型 号:T6131产 地:美洲
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T6193Dovitinib Dilactic AcidDovitinib Dilactic Acid,Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic aci
Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of
价 格:¥电议型 号:T6193产 地:美洲
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T6518GossypolGossypol,BL 193,Pogosin
Gossypol Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
价 格:¥电议型 号:T6518产 地:美洲
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T8498EIDD-1931;化合物EiDD1931Beta-d-N4-hydroxycytidine;Beta-d-N4-hydroxycytidine
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndrome coronavirus (MERS-CoV) in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s =0.1, 0.15 and 0.3 μM, respectively)
价 格:¥电议型 号:T8498产 地:中国大陆
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T83193Acetyl-Heme-Binding Protein 1 (1-21) (human);化合物 Acetyl-Heme-Binding Protein 1 (1-21) (human)Acetyl-
Acetyl-Heme-Binding Protein 1 (1-21) (human) is a short peptide comprising the initial 21 amino acids of the hemopexin Acetyl-Heme-Binding Protein 1, which is involved in heme binding, heme metabolism, and the release of hemoglobin [1].
价 格:¥电议型 号:T83193产 地:中国大陆
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T82193HJM-561;化合物 HJM-561HJM-561
HJM-561 is a potent and selective EGFR PROTAC with oral bioavailability, capable of overcoming osimertinib-resistant EGFR triple mutations and demonstrating anti-tumor activity [1].
价 格:¥电议型 号:T82193产 地:中国大陆
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T81939Leucopelargonidin;化合物 LeucopelargonidinLeucopelargonidin
Leucopelargonidin (compound IV), extracted from Connarus monocarpus [1], is an isolate.
价 格:¥电议型 号:T81939产 地:中国大陆
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T81938Leumorphin, human;化合物 Leumorphin, humanLeumorphin, human
Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum´s myenteric plexus-longitudinal muscle preparation [1].
价 格:¥电议型 号:T81938产 地:中国大陆
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T81937Lewis a trisaccharide;化合物 Lewis a trisaccharideLewis a;Lewis a
Lewis a trisaccharide (Lewis a) constitutes a significant component of the glycan structures on spermatozoa and is also a major constituent of the glycans on the surface of HL-60 cells [1].
价 格:¥电议型 号:T81937产 地:中国大陆
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T81936LFS-1107;化合物 LFS-1107LFS-1107
LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].
价 格:¥电议型 号:T81936产 地:中国大陆
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T81935L-Glutamic γ-monohydroxamate;化合物 L-Glutamic γ-monohydroxamateL-Glutamic γ-monohydroxamate
L-Glutamic γ-monohydroxamate is an antitumor compound that impedes cell proliferation and selectively hinders L-histidine uptake in microvascular endothelial cells. Additionally, this compound serves as a vanadium ligand, enhancing glucose uptake and metabolism, leading to reduced blood glucose levels in vivo [1] [2] [3].
价 格:¥电议型 号:T81935产 地:中国大陆
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T81934Limocitrin 3,7-diglucoside;化合物 Limocitrin 3,7-diglucosideLimocitrin 3,7-diglucoside
Limocitrin 3,7-diglucoside, a flavonoid, has been isolated from the plant Sedum sarmentosum.
价 格:¥电议型 号:T81934产 地:中国大陆
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T81933Limocitrin-3-rutinoside;化合物 Limocitrin-3-rutinosideLimocitrin-3-rutinoside
Limocitrin-3-rutinoside, a flavonoid glycoside, can be isolated from peach fruit [1].
价 格:¥电议型 号:T81933产 地:中国大陆
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T81932LIN28-IN-1;化合物 LIN28-IN-1LIN28-IN-1
LIN28-IN-1 (compound 5) is a selective inhibitor targeting the RNA-binding protein LIN28, specifically binding to its cold shock domain (CSD). This compound robustly interrupts the LIN28-let-7 miRNA interaction with an IC 50 of 5.4 μM, thereby mitigating LIN28´s adverse effects on epigenetic gene control. Furthermore, LIN28-IN-1 exhibits significant anti-proliferative activity against LIN28-expressing JAR cancer cells, evidenced by an IC 50 value of 6.4 μM [1].
价 格:¥电议型 号:T81932产 地:中国大陆
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T81931Linavonkibart;化合物 LinavonkibartLinavonkibart
Linavonkibart (SRK 181) is a fully human antibody with high affinity for latent TGFβ1, selectively binding and inhibiting its activation. This compound is significant in the context of cancer [1].
价 格:¥电议型 号:T81931产 地:中国大陆