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  • T6883SamotolisibInhibitor,mTOR,LY-3023414,Phosphoinositide 3-kinase,DNA-dependent protein kinase,inhibit,

    LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, DNA-PK, and mTOR. LY3023414 has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, BREAST CANCER, and Advanced Cancer, among others.

    价 格：￥电议型 号：T6883产 地：中国大陆

  • T26630Ani9

    Ani9 is a high selective blocker of Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) with an IC50 of 77 nM and can be used in studies about ANO1 and the treatment of ancer, hypertension, pain, diarrhea and asthma.

    价 格：￥电议型 号：T26630产 地：中国大陆

  • T32613LCB 03-0110 dihydrochlorideLCB 030110 dihydrochloride,LCB 03 0110 dihydrochloride

    LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and TGF-β1-induced activation of fibroblasts in vitro, inhibits activation of macrophages and fibroblasts, and inhibits scarring in wound healing models.

    价 格：￥电议型 号：T32613产 地：中国大陆

  • TP1730Lβ-catenin peptide acetate(265669-37-2 free base)βcatenin peptide acetate(265669372 free base),β cate

    β-catenin peptide(βCATp) acetate is a naturally occurring self-peptide presented by Kb that very efficiently mediates positive selection of the OT-I thymocytes.

    价 格：￥电议型 号：TP1730L产 地：中国大陆

  • T22303Dasatinib hydrochloride

    Dasatinib hydrochloride (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib hydrochloride hydrochloride also induces Apoptosis and Autophagy.

    价 格：￥电议型 号：T22303产 地：中国大陆

  • T13012Stearyldiethanolamine

    Stearyldiethanolamine can be used in studies about antibacterial nonwoven fabric and antibacterial freshness-keeping film.

    价 格：￥电议型 号：T13012产 地：中国大陆

  • T6668SGC-CBP30inhibit,IL-17A,HAT,HATs,BRD,Histone Acetyltransferase,ankylosing,SGCCBP30,cells,epigenetic,

    SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).

    价 格：￥电议型 号：T6668产 地：中国大陆

  • T6588Mitoxantroneleukaemia,NSC301739,PKC,MCF-7,NSC 301739,lymphocytes,Topoisomerase,Mitoxantrone,HL60 cel

    Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.

    价 格：￥电议型 号：T6588产 地：中国大陆

  • T30855CGP77675

    CGP77675 is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and autophosphorylation of purified Src. CGP77675 exhibits anticancer activity.

    价 格：￥电议型 号：T30855产 地：中国大陆

  • TN30915,7-Diacetoxy-8-methoxyflavone

    5,7-Diacetoxy-8-methoxyflavone is derived from the roots of Scutellaria baicalensis and inhibits cAMP phosphodiesterase.

    价 格：￥电议型 号：TN3091产 地：中国大陆

  • T7330Nucleozininhibit,Nucleozin,viral,Inhibitor,infection,Influenza Virus,nuclear,nucleoprotein,virus,rep

    Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.

    价 格：￥电议型 号：T7330产 地：中国大陆

  • T8930CID44216842diseases,neutrophils,ovarian,disorders,Cdc42,fibroblasts,breast,hepatitis C,CID 44216842,

    CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.

    价 格：￥电议型 号：T8930产 地：中国大陆

  • T15830M-110M 110,M110

    M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM.

    价 格：￥电议型 号：T15830产 地：中国大陆

  • T6630Quercetin DihydrateInhibitor,PI3K,Phosphoinositide 3-kinase,Quercetin Dihydrate,Apoptosis,inhibit

    Quercetin is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effects.

    价 格：￥电议型 号：T6630产 地：中国大陆

  • TP1530LYRGDS Fibronectin Fragment acetateYRGDS Fibronectin Fragment acetate

    This is a fibronectin fragment acetate, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets. It is RGD consisting of sequence.

    价 格：￥电议型 号：TP1530L产 地：中国大陆

  • T23010MNI 137MNI 137

    MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.

    价 格：￥电议型 号：T23010产 地：中国大陆

  • T9264ECBN HCLInhibitor,inhibit,ECBN HCL,A-30912A nucleus

    A-30912A nucleus hydrochloride is the reaction product catalyzed by Echinocandin B (ECB) deacylase.

    价 格：￥电议型 号：T9264产 地：中国大陆

  • T7304DNQXinhibit,nucleus,selective,thalamic,Ionotropic glutamate receptors,Inhibitor,quinoxaline,DNQX,FG-

    DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)

    价 格：￥电议型 号：T7304产 地：中国大陆

  • TN2330Phenethyl ferulatePhenethyl ferulate,Lipoxygenase,5-LOX,Cyclooxygenase,Inhibitor,5-lipoxygenase,inhi

    Caffeic Acid 3-Methyl Phenethyl Ester has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane induced colon tumors. It shows inhibitory activity against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50 values of 4.35 μM and 5.75 μM, respectively.

    价 格：￥电议型 号：TN2330产 地：中国大陆

  • T11230ERRα antagonist-1

    ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.

    价 格：￥电议型 号：T11230产 地：中国大陆

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