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  • T12424PF-06305591

    PF-06305591 is an effective and selective blocker of voltage-gated sodium channel NaV1.8 (IC50 = 15 nM).

    价 格：￥电议型 号：T12424产 地：中国大陆

  • T14303Alrizomadlin

    Alrizomadlin is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.

    价 格：￥电议型 号：T14303产 地：中国大陆

  • T7305JQEZ5S-adenosyl,EZH2,JQEZ5,antitumor,methionine,JQEZ 5,H3K27me3,PRC2,inhibit,Inhibitor,JQEZ-5,Histon

    JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).

    价 格：￥电议型 号：T7305产 地：中国大陆

  • T8309EIDD-2801EIDD 2801,EIDD2801

    EIDD-2801 is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multiple coronaviruses activity.

    价 格：￥电议型 号：T8309产 地：中国大陆

  • T3079GSK1838705ACD246,Anaplastic lymphoma kinase,inhibit,Cluster of differentiation 246,Anaplastic lympho

    GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.

    价 格：￥电议型 号：T3079产 地：中国大陆

  • T9630WAY-312858WAY312858,WAY 312858

    WAY-312858 is a chemical agent.

    价 格：￥电议型 号：T9630产 地：中国大陆

  • T7393ONO-7300243ONO7300243,inhibit,Inhibitor,ONO 7300243,ONO-7300243,LPL Receptor,Lysophospholipid Recept

    ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).

    价 格：￥电议型 号：T7393产 地：中国大陆

  • T63049CHD1Li 6.11

    CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor. CHD1Li 6.11 exhibits IC50 of 3.3 ?M for cat-CHD1L recombinant protein. CHD1Li 6.11 is an orally bioavailable antitumor agent. CHD1Li 6.11 significantly reduces the tumor volume of CRC xenografts, which is generated from isolated quasi mesenchymal cells (M-phenotype).

    价 格：￥电议型 号：T63049产 地：中国大陆

  • T13303Virginiamycin M1

    Virginiamycin M1 is a macrocyclic lactone peptide antibiotic and is a member of the streptogramin A group of antibiotics.

    价 格：￥电议型 号：T13303产 地：中国大陆

  • T0030LBupivacaine

    Bupivacaine is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain.

    价 格：￥电议型 号：T0030L产 地：中国大陆

  • T23005MM 11253

    MM 11253 is a RARγ antagonist with IC50 of 44nM.

    价 格：￥电议型 号：T23005产 地：中国大陆

  • TP2307Pinealon AcetatePinealon Acetate

    Pinealon Acetategland has antioxidant activity and can directly interact with the cell genome.

    价 格：￥电议型 号：TP2307产 地：中国大陆

  • T6430CalcifediolVitamin D receptor,Calcifediol,VD/VDR,Vitamin D,Inhibitor,inhibit,Endogenous Metabolite

    Calcifediol(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.

    价 格：￥电议型 号：T6430产 地：中国大陆

  • T6568LicofeloneLicofelone,Lipoxygenase,ML 3000,LOX,Apoptosis,COX,Inhibitor,inhibit,ML3000,Cyclooxygenase

    Licofelone is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase).

    价 格：￥电议型 号：T6568产 地：中国大陆

  • T13037Sulindac sulfideSulindac sulfide

    Sulindac sulfide is an inhibitor of noncompetitive γ-secretase(IC50 of 20.2 μM for γ42-secretase activity).

    价 格：￥电议型 号：T13037产 地：中国大陆

  • T9659LCB 03-0110LCB 030110,LCB 03 0110

    LCB 03-0110 is a potent inhibitor of discoidin domain receptor family tyrosine kinases and strongly inhibits several tyrosine kinases, including the c-Src family, spleen tyrosine kinase, Bruton´s tyrosine kinase, and vascular endothelial growth factor receptor 2, which are important for immune cell signaling and inflammatory reactions.

    价 格：￥电议型 号：T9659产 地：中国大陆

  • T61301Chromenone 1

    Chromenone 1 is a potent potentiator of osteogenic bone morphogenetic protein (BMP). Chromenone 1 induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs.

    价 格：￥电议型 号：T61301产 地：中国大陆

  • T8515OsoresnontrineOsoresnontrine,Inhibitor,BI409306,Phosphodiesterase (PDE),inhibit,BI 409306

    BI-409306 is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory

    价 格：￥电议型 号：T8515产 地：中国大陆

  • T60130USP5-IN-1USP5IN1

    USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor, which binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1].

    价 格：￥电议型 号：T60130产 地：中国大陆

  • TJS0405LucidinInhibitor,Lucidin,NSC-30546,NSC30546,inhibit

    1. Lucidin and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.

    价 格：￥电议型 号：TJS0405产 地：中国大陆

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