T6588Mitoxantroneleukaemia,NSC301739,PKC,MCF-7,NSC 301739,lymphocytes,Topoisomerase,Mitoxantrone,HL60 cel

Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.

价 格：￥电议型 号：T6588产 地：中国大陆

T26520ABP688ABP688

ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.

价 格：￥电议型 号：T26520产 地：中国大陆

T6571Lomerizine dihydrochlorideCa2+ channels,Ca channels,inhibit,Lomerizine,KB 2796,KB2796,Lomerizine dih

Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.

价 格：￥电议型 号：T6571产 地：中国大陆

T36527IL-4-inhibitor-1IL4inhibitor1,IL 4 inhibitor 1

IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50= 3.1 μM), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway.

价 格：￥电议型 号：T36527产 地：中国大陆

T6560Lappaconitine hydrobromideLappaconitine hydrobromide

Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects.

价 格：￥电议型 号：T6560产 地：中国大陆

T6387AmpiroxicamAmpiroxicam,COX,inhibit,CP65703,Cyclooxygenase,CP-65703,Inhibitor

Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.

价 格：￥电议型 号：T6387产 地：中国大陆

T8890653-47 hydrochlorideInhibitor,transcription,65347 hydrochloride,Epigenetic Reader Domain,inhibit,CRE

653-47 hydrochloride is a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. It is also a very weak CREB inhibitor with IC50 of 26.3 μM.

价 格：￥电议型 号：T8890产 地：中国大陆

T6584MG 149HAT,Inhibitor,MG 149,Epigenetic Reader Domain,Apoptosis,HATs,inhibit,Histone Acetyltransferase

MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).

价 格：￥电议型 号：T6584产 地：中国大陆

T9765TJ-M2010-5ischemia,MIRI,Anoxia,factor,MyD88,injury,reoxygenation,inhibit,reperfusion,differentiation

TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.

价 格：￥电议型 号：T9765产 地：中国大陆

T6652Salbutamol hemisulfateAdrenergic Receptor,Beta Receptor,Inhibitor,Salbutamol hemisulfate,AH-3365 hem

Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.

价 格：￥电议型 号：T6652产 地：中国大陆

TN65525,7-Dimethoxyluteolin5,7-dimethylluteolin,5,7 Dimethoxyluteolin,Dopamine Transporter,SLC6A3,DAT,5,7-

5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. 5,7-Dimethoxyluteolin is a dopamine transporter (DAT) activator with an EC50 of 3.417 μM.

价 格：￥电议型 号：TN6552产 地：中国大陆

Fr212652-Methyl-2H-indazole-3-carboxylic acid

价 格：￥电议型 号：Fr21265产 地：中国大陆

T6566Levobupivacaine hydrochlorideCNS toxicity,gastric cancer,Na channels,Erastin,Inhibitor,analgesic,ana

Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic.

价 格：￥电议型 号：T6566产 地：中国大陆

T7265HSP27 inhibitor J2Heat shock proteins,inhibit,HSP-27 inhibitor J2,HSP27 inhibitor J2,Inhibitor,J 2,H

HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function.

价 格：￥电议型 号：T7265产 地：中国大陆

T8824CRBN modulator-1CRBN modulator1,CRBN modulator-1,inhibit,CRBN modulator 1,Ligands for E3 Ligase,E3 l

WUN29654 is a Thalidomide analog and CRBN modulator,has an IC50 of 3.5 μM and a Ki of 0.98 μM.

价 格：￥电议型 号：T8824产 地：中国大陆

Fr14565Compound Fr14565Compound Fr14565

价 格：￥电议型 号：Fr14565产 地：中国大陆

T6997SU6656PTK2 protein tyrosine kinase 2,Focal adhesion kinase,FAK,Akt,SU-6656,PTK2,Inhibitor,Protein ki

SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.

价 格：￥电议型 号：T6997产 地：中国大陆

T6577ManidipineCalcium Channel,Manidipine,Inhibitor,inhibit,Ca channels,Ca2+ channels

Manidipine, a calcium channel blocker, which is dihydropyridine type. It is utilized

价 格：￥电议型 号：T6577产 地：中国大陆

T6653Salmeterol Xinafoatecorticosteroid,Salmeterol,Beta Receptor,therapy,inhibit,Adrenergic Receptor,GR 3

Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms.

价 格：￥电议型 号：T6653产 地：中国大陆

T6654SaponinsSaponins,Inhibitor,Fungal,inhibit,Bacterial

Sapogenins glycosides are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effective for the treatment/prevention of venous insufficiency.

价 格：￥电议型 号：T6654产 地：中国大陆