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  • T79672DUB-IN-7；化合物 DUB-IN-7DUB-IN-7

    DUB-IN-7 (compound 43), a deubiquitinating enzyme (DUB) inhibitor, has utility in researching diseases driven by aberrant JAK2 activity, including leukemia [1].

    价 格：￥电议型 号：T79672产 地：中国大陆

  • T79442DprE1-IN-7；化合物 DprE1-IN-7DprE1-IN-7

    DprE1-IN-7 (Compound 64) is a DprE1 inhibitor with potent anti-tuberculosis (TB) activity, demonstrating a minimum inhibitory concentration (MIC) of 1 μM against the Mtb H37Rv strain. It exhibits antimycobacterial effects on drug-resistant strains. Additionally, DprE1-IN-7 shows high microsomal stability and exhibits medium clearance [1].

    价 格：￥电议型 号：T79442产 地：中国大陆

  • T77764DC-Y13-27；化合物DC-Y13-27DC-Y13-27

    Dc-y13-27, a derivative of DC-Y13, is a potent YTHDF2 inhibitor (KD: 37.9 μM). DC-Y13-27 has antitumor activity that enhances the response of radiotherapy and immunotherapy to tumors.

    价 格：￥电议型 号：T77764产 地：中国大陆

  • T7747Datelliptium chloride hydrochloride；化合物T7747Datelliptium chloride hydrochloride

    Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.

    价 格：￥电议型 号：T7747产 地：中国大陆

  • T74682U7D-1；化合物 U7D-1U7D-1

    U7D-1, a groundbreaking and selective ubiquitin-specific protease 7 (USP7) PROTAC degrader, exhibits a DC50 value of 33 nM in RS4;11 cells, demonstrating its potent anticancer properties. Furthermore, U7D-1 effectively induces apoptosis in Jeko-1 cells [1].

    价 格：￥电议型 号：T74682产 地：中国大陆

  • T74556dTAG-47；化合物 dTAG-47dTAG-47

    dTAG-47, a heterobifunctional molecule, specifically targets the mutant FKBP12 (FKBP12 F36V), which functions as a degradation tag (dTAG) when fused to a protein of interest. This compound is utilized in the study of basal-like breast cancers (BBC) [1].

    价 格：￥电议型 号：T74556产 地：中国大陆

  • T73469SG2057；化合物 SG2057DRG16；DRG16

    SG2057 (DRG16), a potent antitumor agent, is a pyrrolobenzodiazepine (PBD) dimer connected by a pentyldioxy linkage. This compound selectively binds to the minor groove of DNA, forming both interstrand and intrastrand cross-linked adducts, contributing to its high antitumor activity.

    价 格：￥电议型 号：T73469产 地：中国大陆

  • T73456DRP1i27；化合物 DRP1i27DRP1i27

    DRP1i27, a potent human dynamin-related protein 1 (Drp1) inhibitor, targets the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. It mitigates Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.

    价 格：￥电议型 号：T73456产 地：中国大陆

  • T73437DP00477；化合物 DP00477DP00477

    DP00477, a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibits an inhibitory concentration (IC50) of 7.0 ?M. This compound holds promise for cancer research applications.

    价 格：￥电议型 号：T73437产 地：中国大陆

  • T73311DENV-IN-7；化合物 DENV-IN-7DENV-IN-7

    DENV-IN-7, a flavone analog, functions as an inhibitor of the dengue virus (DENV), demonstrating anti-dengue activity with an effective concentration (EC50) of 70 nM while exhibiting low toxicity against normal cells.

    价 格：￥电议型 号：T73311产 地：中国大陆

  • T73132DS69910557；化合物 DS69910557DS69910557

    DS69910557, a potent, selective, and orally active antagonist of the human parathyroid hormone receptor 1 (hPTHR1), exhibits antagonistic activity with an IC50 value of 0.08 μM. It is useful in researching hyperparathyroidism, hypercalcemia of malignancy, and osteoporosis.

    价 格：￥电议型 号：T73132产 地：中国大陆

  • T71585DB03417；化合物 DB03417DB03417

    DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor.

    价 格：￥电议型 号：T71585产 地：中国大陆

  • T71246DD04107；化合物 DD04107DD04107

    DD04107 is a novel inhibitor of α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons, selectively interacting with Synaptotagmin 1.

    价 格：￥电议型 号：T71246产 地：中国大陆

  • T71108TLR7/8 agonist 1；化合物 TLR7/8 agonist 7dTLR7/8 agonist 1

    TLR7/8 agonist 1 is a toll-like receptor ( TLR7 )/ TLR8 dual-agonistic imidazoquinoline.

    价 格：￥电议型 号：T71108产 地：中国大陆

  • T71061DSM267；化合物 DSM267DSM267

    DSM267 is a novel Plasmodium falciparum Dihydroorotate Dehydrogenase (PfDHODH) Inhibitor.

    价 格：￥电议型 号：T71061产 地：中国大陆

  • T69643DGY-08-097；化合物 DGY-08-097DGY-08-097

    DGY-08-097 is a novel HCV NS3 degrader, reducing susceptibility to resistance mutations, potently inhibiting HCV in a cellular infection model, exhibiting the most potent degradation (DC50 of 50nM at 4h) of HCV NS3.

    价 格：￥电议型 号：T69643产 地：中国大陆

  • T69409DH-97；化合物 DH-97DH-97

    DH-97 is a potent MT2 melatonin receptor antagonist (pKi value = 8.03).

    价 格：￥电议型 号：T69409产 地：中国大陆

  • T69275DOV-102677；化合物 DOV-102677DOV-102677

    DOV-102677 is a psychoactive drug being developed by Merck and is currently in clinical trials. It is a triple reuptake inhibitor, or serotonin-norepinephrine-dopamine reuptake inhibitor. It is the-enantiomer of DOV-216,303, and its-enantiomer is DOV-21,947.

    价 格：￥电议型 号：T69275产 地：中国大陆

  • T64606TLR7/8 agonist-7d；化合物 TLR7/8 agonist-7dTLR7/8 agonist-7d

    TLR7/8 agonist-7d is a useful organic compound for research related to life sciences and the catalog number is T64606.

    价 格：￥电议型 号：T64606产 地：中国大陆

  • T62915Dot1L-IN-7；化合物 Dot1L-IN-7Dot1L-IN-7

    Dot1L-IN-7 (compound 25) is a selective and potent inhibitor of telomere silencing 1-like protein (DOT1L) (IC50: 1.0 μM).Dot1L-IN-7 selectively kills MLL-AF9 and does not affect the growth of E2A-HLF cells.

    价 格：￥电议型 号：T62915产 地：中国大陆

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