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T17757DBCO-NHCO-C4-NHS ester；化合物 T17757DBCO-NHCO-C4-NHS ester
DBCO-NHCO-C4-NHS ester is an alkyl chain-derived PROTAC linker applicable for PROTACs synthesis[1].
价 格：￥电议型 号：T17757产 地：中国大陆
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T17747DBCO-C3-PEG4-NH-Boc；化合物 T17747DBCO-C3-PEG4-NH-Boc
DBCO-C3-PEG4-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17747产 地：中国大陆
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T15181DuP-697；化合物DuP-697DuP-697
DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic, anti-inflammatory, antipyretic and apoptotic effects.
价 格：￥电议型 号：T15181产 地：中国大陆
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T15147DNMDP；化合物 T15147DNMDP
DNMDP is a phosphodiesterase 3A inhibitor with clear cell-selective cytotoxicity. DNMDP binding to PDE3A promotes interaction between PDE3A and Schlafen 12.
价 格：￥电议型 号：T15147产 地：中国大陆
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T15077DBCO-Sulfo-Link-biotin；化合物 T15077DBCO-Sulfo-Link-biotin
DBCO-Sulfo-Link-biotin is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格：￥电议型 号：T15077产 地：中国大陆
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T15057DBCO-acid；化合物 T15057DBCO-acid
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester, and drug-linker conjugates DBCO-PEG-MMAE[1].
价 格：￥电议型 号：T15057产 地：中国大陆
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T13657dMCL1-2；化合物 T13657dMCL1-2
dMCL1-2 is a potent and selective myeloid leukemia 1 (MCL1) degrading agent based on PROTAC, which binds to MCL1 with a KD of 30 nM. dmcl-2 activates the apoptosis mechanism by degrading MCL1.
价 格：￥电议型 号：T13657产 地：中国大陆
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T12337Oxaquin；化合物 T12337DNV3837|||MCB-3837；DNV3837|||MCB-3837
Oxaquin is an effective, water-soluble, injectable prodrug that is rapidly converted to the active substance MCB3681 after intravenous administration in the body. Oxaquin is active against Gram-positive bacteria, but has no antibacterial effect on its own.
价 格：￥电议型 号：T12337产 地：中国大陆
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T12147N-Desmethyl Clomipramine hydrochloride；化合物 T12147Desmethylclomipramine hydrochloride；Desmethylclomip
N-Desmethyl Clomipramine hydrochloride is a primary plasma N-desmethyl Clomipramine metabolite .
价 格：￥电议型 号：T12147产 地：中国大陆
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T11107DSP-1053；化合物 T11107DSP-1053
Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.
价 格：￥电议型 号：T11107产 地：中国大陆
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T11101DS08210767；化合物DS08210767DS08210767
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
价 格：￥电议型 号：T11101产 地：中国大陆
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T11057DM3-SMe；化合物 T11057DM3-SMe
DM3-SMe is a maytansine derivative and tubulin inhibitor. It is a cytotoxic part of antibody-drug conjugates (ADCs) and can bind to antibodies via disulfide bonds or stable thioether bonds. DM3-SMe has high cytotoxic activity in vitro with IC50 of 0.0011 nM.
价 格：￥电议型 号：T11057产 地：中国大陆
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T11037Diacylglycerol acyltransferase inhibitor-1；化合物 T11037Diacylglycerol acyltransferase inhibitor-1
Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.
价 格：￥电议型 号：T11037产 地：中国大陆
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T11031hDHODH-IN-7；化合物hDHODH-IN-7DHODH-IN-9；DHODH-IN-9
hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects.
价 格：￥电议型 号：T11031产 地：中国大陆
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T11017DGN462；化合物 T11017DGN462
DGN462 is an effective DNA alkylating agent with anti-tumor activity, as in acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T11017产 地：中国大陆
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T11007Desmethyl Levofloxacin；化合物 T11007Desmethyl Levofloxacin
Desmethyl Levofloxacin is a metabolite of levofloxacin. Levofloxacin is a synthetic fluoroquinolone drug, an antibacterial agent that can inhibit the super-coiling activity of bacterial DNA gyrase and prevent DNA replication.
价 格：￥电议型 号：T11007产 地：中国大陆
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T10967DC_C66；化合物 T10967DC_C66
DC_C66 DC_C66 has good selectivity for CARM1, PRMT1 (IC50 = 21μM), PRMT6 (IC50 = 47μM) and PRMT5. It is a cell-permeable, selective co-activator related arginine methyltransferase 1 (CARM1) inhibitor with IC50 of 1.8 μM.
价 格：￥电议型 号：T10967产 地：中国大陆
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T10957Dapagliflozin impurity；化合物 T10957Dapagliflozin impurity
Dapagliflozin impurity is the enantiomer of Dapagliflozin, Dapagliflozin is a sodium glucose transporter 2 inhibitor.
价 格：￥电议型 号：T10957产 地：中国大陆
