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T73105EGFR-IN-28;化合物 EGFR-IN-28EGFR-IN-28
EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity [1] .
价 格:¥电议型 号:T73105产 地:中国大陆
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T72944eIF4A3-IN-18;化合物 eIF4A3-IN-18eIF4A3-IN-18
eIF4A3-IN-18, a silvestrol analogue, disrupts the formation of the eIF4F translation complex, exhibiting EC 50 values of 0.8, 35, and 2 nM for myc-LUC, tub-LUC, and the growth inhibition of MBA-MB-231 cells, respectively. Additionally, it demonstrates cytotoxicity towards RMPI-8226 cells with an LC 50 of 0.06 nM. This compound is utilized in researching human cancer pathogenesis [1].
价 格:¥电议型 号:T72944产 地:中国大陆
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T71316ERK Inhibitor II (Negative control);化合物 QUN-70738ERK Inhibitor II (Negative control)
ERK Inhibitor II (Negative control) effectively blocks extracellular signal-regulated kinase (ERK) and interferes with insulin receptor activation, serving as a useful tool in diabetes research.
价 格:¥电议型 号:T71316产 地:中国大陆
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T68768EMD-23448;化合物 EMD-23448EMD-23448
EMD-23448 is a dopamine autoreceptor agonist as potential antipsychotics.
价 格:¥电议型 号:T68768产 地:中国大陆
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T64307EZH2-IN-8;化合物 EZH2-IN-8EZH2-IN-8
EZH2-IN-8 is a potent inhibitor of EZH2. EZH2-IN-8 has the potential to be used in the study of cancer diseases.
价 格:¥电议型 号:T64307产 地:中国大陆
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T64255EGFR-IN-48;化合物 EGFR-IN-48EGFR-IN-48
EGFR-IN-48 is a potent, orally active EGFR inhibitor that acts on EGFRd19/TM/CS (IC50: 0.193 nM), EGFRLR/TM/CS (IC50: 0.251 nM), EGFRWT (IC50: 10.4 nM). EGFR-IN-48 is also able to inhibit EGFR-IN-48 also inhibits the proliferation of BaF3EGFR del19/T790M/C797S cells (IC50: 1.526 nM) and PC-9EGFR del19/T790M/C797S cells (IC50: 66.7 nM).
价 格:¥电议型 号:T64255产 地:中国大陆
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T64170EGFR-IN-18;化合物 EGFR-IN-18EGFR-IN-18
EGFR-IN-18 is a potent inhibitor of the enzymatic activity of the L858R/T790M/C797S mutant EGFR (4.9 nM) and is also able to reduce the enzymatic activity of wild-type EGFR (47 nM).
价 格:¥电议型 号:T64170产 地:中国大陆
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T63774EGFR-IN-58;化合物 EGFR-IN-58EGFR-IN-58
EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.
价 格:¥电议型 号:T63774产 地:中国大陆
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T63331ERK1/2 inhibitor 8;化合物 ERK1/2 inhibitor 8ERK1/2 inhibitor 8
ERK1/2 inhibitor 8 is a potent inhibitor of ERK that acts on ERK2 (IC50: 0.48 nM).
价 格:¥电议型 号:T63331产 地:中国大陆
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T63283EGFR-IN-38;化合物 EGFR-IN-38EGFR-IN-38
EGFR-IN-38 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR. Among others, overexpression and mutation of the epidermal growth factor receptor (EGFR) has been shown to lead to uncontrolled cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-38 exhibits potential for research in EGFR mutation-related diseases.
价 格:¥电议型 号:T63283产 地:中国大陆
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T62459Enpp-1-IN-8;化合物 Enpp-1-IN-8Enpp-1-IN-8
Enpp-1-IN-8 is a potent ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1) inhibitor. ENPP 1 has broad specificity and cleaves a wide range of substrates (including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars). Enpp-1-IN-8 has potential for cancer and infectious disease studies.
价 格:¥电议型 号:T62459产 地:中国大陆
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T61267EGFR-IN-68;化合物 EGFR-IN-68EGFR-IN-68
EGFR-IN-68 (Compound 8d) is a highly effective EGFR inhibitor, demonstrated by its potent inhibition activity with an IC50 value of 0.33 μM. It exhibits notable anticancer properties [1].
价 格:¥电议型 号:T61267产 地:中国大陆
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T61179EMI48;化合物 EMI48EMI48
EMI48, a derivative of EMI1, exhibits increased efficacy against mutant EGFR compared to EMI1. It specifically inhibits EGFR triple mutants [1].
价 格:¥电议型 号:T61179产 地:中国大陆
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T60938EGFR/HER2-IN-8;化合物 EGFR/HER2-IN-8EGFR/HER2-IN-8
EGFR/HER2-IN-8 (compound 34) is an inhibitor of EGFR/HER2 and DHFR with IC50 values of 0.45, 0.244 and 5.669 μM for EGFR, HER2 and DHFR, respectively. EGFR/HER2-IN-8 can be used in the cancer research that exhibits anticancer activity against several cancer cell lines with high safety profile and selectivity indices [1].
价 格:¥电议型 号:T60938产 地:中国大陆
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T57068-epidiosbulbin E acetate8-表黄独素E乙酸酯8epidiosbulbin E acetate|||8 epidiosbulbin E acetate|||8-epidiosb
8-epidiosbulbin E acetate is an abundant diterpene lactone in Dioscorea bulbifera L. (DB), a traditional herbal medicine widely used in Asian countries.
价 格:¥电议型 号:T5706产 地:中国大陆
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T4659ELN484228;化合物ELN484228ELN484228
ELN484228 is a α-synuclein blocker. α-synuclein is a key protein in Parkinson’s disease.
价 格:¥电议型 号:T4659产 地:中国大陆
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T382131-β-D-Glucosylsphingadienine (d18:2 (4E,8E));1-β-D-Glucosylsphingadienine (d18:2 (4E,8E))1-β-D-Gluco
1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher&
价 格:¥电议型 号:T38213产 地:中国大陆
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T37826CAY10462;化合物CAY10462CAY10462|||CTK8E8405;CAY10462|||CTK8E8405
CAY10462 (CTK8E8405) is an effective and selective inhibitor of the 20-HETE synthase CYP4A11 with an IC50 of 8.8 nM. CAY10462 exhibits nearly 200 times less potent for 1A, 1C, and 3A CYP450 enzymes.
价 格:¥电议型 号:T37826产 地:中国大陆
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T34979U-34728E (HCl);化合物 T34979U 34728E (HCl);U 34728E (HCl)
U-34728E (HCl) is a bioactive chemical.
价 格:¥电议型 号:T34979产 地:中国大陆