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T7329C-178MITA,inhibit,Inhibitor,STING,MPYS,C178,ERIS,C-178,C 178,Stimulator of Interferon Genes,TMEM173
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.
价 格：￥电议型 号：T7329产 地：中国大陆
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TP2131LRac1 Inhibitor W56 acetate(1095179-01-3 free base)Rac1 Inhibitor W56 acetate(1095179013 free base),R
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1.
价 格：￥电议型 号：TP2131L产 地：中国大陆
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TP2112LTC14012 acetateTC-14012 acetate,TC14012 acetate
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent CXCR7 agonist with an EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. TC14012 has anti-cancer activity and anti-HIV activity.
价 格：￥电议型 号：TP2112L产 地：中国大陆
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T60904ERCC1-XPF-IN-2
ERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 μM [1].
价 格：￥电议型 号：T60904产 地：中国大陆
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T6594MNSthrombin,aggregation,NSC170724,Inhibitor,Src,MNS,NSC 170724,activation,inhibit,NSC-170724,Spleen
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
价 格：￥电议型 号：T6594产 地：中国大陆
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TN1362AfzelinPTEN,MMAC1,Afzelin,Phosphatase and tensin homolog,inhibit,Autophagy,Inhibitor,Bacterial,Mitoc
Afzelin has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced damage by a combination of UV-absorbing and cellular activities. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1.
价 格：￥电议型 号：TN1362产 地：中国大陆
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T7953BpV(HOpic)MAPK/ERK,Phosphatase and tensin homolog,Inhibitor,PTEN,MMAC1,inhibit,PI3K/AKT,BpV(HOpic),s
bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).
价 格：￥电议型 号：T7953产 地：中国大陆
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T13254LUNC10217938A HCl
UNC10217938A HCl is a 3-deazapteridine analog. UNC10217938A HCl exhibits strong oligonucleotide enhancing effects. UNC10217938A HCl can modulate their intracellular trafficking and release from endosomes, leading to enhance oligonucleotides effects. UNC10217938A HCl also enhances the effects of siRNA and antisense oligonucleotides.
价 格：￥电议型 号：T13254L产 地：中国大陆
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T37575GLcNAc1-b-PNP4NitrophenylNacetylβDglucosaminide,4 Nitrophenyl N acetyl β D glucosaminide
GLcNAc1-b-PNP is a chromogenic substrate for N-acetyl-β-glucosaminidase and can be used to quantify the activity of N-acetyl-β-D-glucosaminidase in human serum and urine.
价 格：￥电议型 号：T37575产 地：中国大陆
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T8528AC1903Inhibitor,glomerulosclerosis,proteinuria,inhibit,TRP Channel,ros,focal segmental,AC 1903,Trans
AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.
价 格：￥电议型 号：T8528产 地：中国大陆
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T37562C16 Ceramide
C16 Ceramide is a natural small molecule activating p53 through the direct and selective binding.
价 格：￥电议型 号：T37562产 地：中国大陆
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T8706BC-1471BC1471,BC 1471
BC-1471 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism.
价 格：￥电议型 号：T8706产 地：中国大陆
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T9781Boc-C14-COOHADC Linkers,Antibody-drug conjugates linkers,Inhibitor,PROTAC Linkers,inhibit,Boc-C-14-C
Boc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T9781产 地：中国大陆
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TP1097Melanotan IInhibitor,MC1R,Melanocortin Receptor,skin cancers,α-MSH,melanotropic peptide,Melanotan,Me
Melanotan-I has the amino acid sequence of Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val and a molecular weight of 1647.4 Dalton.
价 格：￥电议型 号：TP1097产 地：中国大陆
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T9276SBC-115337SBC115337,Serine endopeptidases,benzofuran,LDLR,Threonine proteases,SBC-115337,Ser/Thr Pro
SBC-115337 is a PCSK9 inhibitor.
价 格：￥电议型 号：T9276产 地：中国大陆
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TP1072ValinomycinNSC-122023,Apoptosis,Bacterial,Autophagy,Inhibitor,inhibit,Valinomycin,Antibiotic,NSC1220
Valinomycin is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65.
价 格：￥电议型 号：TP1072产 地：中国大陆
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T6S1740Nardosinonecells,Nardosinone,Neurite,substances,PC12D,outgrowth-promoting,neuritogenic,inhibit,MAPK,
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and stau
价 格：￥电议型 号：T6S1740产 地：中国大陆
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T8527CPYPPDOCK2,CPYPP,Inhibitor,GEF,Rac1,DOCK180,lymphocytes,autoimmune,DOCK2-Rac1,inhibit,DOCK5,immunosu
CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 μM). CPYPP also inhibits DOCK180, DOCK5 and less DOCK9
价 格：￥电议型 号：T8527产 地：中国大陆
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T10989Dehydroaripiprazoleinhibit,antipsychotic,OPC14857,OPC 14857,Dehydroaripiprazole,CYP3A4,Inhibitor,Met
Dehydroaripiprazole is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mainly forms dehydroaripiprazole. Dehydroaripiprazole has antipsychotic activity equivalent to aripiprazole.
价 格：￥电议型 号：T10989产 地：中国大陆
