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T4S124714-Hydroxy sprengerinin C14-Hydroxy sprengerinin C,Inhibitor,inhibit,14Hydroxy sprengerinin C,14 Hyd
14-Hydroxy sprengerinin C is a natural product from Ophiopogon japonicus.
价 格:¥电议型 号:T4S1247产 地:中国大陆
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T8800NSAHDNA/RNA Synthesis,HCT116,MDA-231,Panc1,Inhibitor,NSAH,inhibit,S-phase
NSAH is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.
价 格:¥电议型 号:T8800产 地:中国大陆
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T9061EN4EN4,ligand,Myc,tumorigenesis,transcriptional,inhibit,Inhibitor,EN 4,covalent,C171,c-Myc,EN-4
EN4 MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis.
价 格:¥电议型 号:T9061产 地:中国大陆
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T23601ABC1183ABC1183
ABC1183 is a novel diaminothiazole that inhibits GSK3α, GSK3β and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival by inducing G2/M arrest and through altering GSK3, glycogen synthetase, β-catenin phosphorylation and MCL1 expression,and is orally active.
价 格:¥电议型 号:T23601产 地:中国大陆
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T9117BSJ-4-116CDK,degrader,antiproliferative,inhibit,Kelly,C1039F,BSJ 4 116,Cyclin dependent kinase,PROTA
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).
价 格:¥电议型 号:T9117产 地:中国大陆
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T8827EMAC10101dEMAC-10101d,Carbonic Anhydrase,hCA II,EMAC10101d,Inhibitor,inhibit,Carbonate dehydratase
compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an inhibitory activity in the low nanomolar range.
价 格:¥电议型 号:T8827产 地:中国大陆
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T60003AC1-IN-1Adenylyl cyclase,Adenylate Cyclase,Inhibitor,AC1IN1,Chronic Pain,inhibit,antiallodynic,nonto
AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 ?M).
价 格:¥电议型 号:T60003产 地:中国大陆
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T13102TCMDC-135051TCMDC135051,TCMDC 135051
TCMDC-135051 is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC50=320 nM).
价 格:¥电议型 号:T13102产 地:中国大陆
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T7495Hexa-D-arginineinhibit,furin,Furin Inhibitor II,TNF-α,PACE4,noncytotoxic,PC1,anthrax,PEA,HexaDargini
Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.
价 格:¥电议型 号:T7495产 地:中国大陆
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T6801CeMMEC13Inhibitor,CeMMEC13,DNA/RNA Synthesis,CeMMEC-13,CeMMEC 13,inhibit
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
价 格:¥电议型 号:T6801产 地:中国大陆
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TQ0211BrusatolNrf2,oxygen,CT-26,NSC172924,NSC-172924,defense,stress,Keap1-Nrf2,Brusatol,chemosensitization
Brusatol is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
价 格:¥电议型 号:TQ0211产 地:中国大陆
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T17021Tebipeneminhibit,LJC11036,Bacterial,LJC-11036,Antibiotic,Inhibitor
Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.
价 格:¥电议型 号:T17021产 地:中国大陆
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T6411BiapenemL627,inhibit,L-627,CLI86815,LJC10627,Bacterial,LJC-10627,Antibiotic,CLI-86815,Biapenem,Inhib
Biapenem is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. Biapenem has similar antibacterial activity to that of imipenem, but is more stable against human renal dehydropeptidase-I and with less neurotoxicity.
价 格:¥电议型 号:T6411产 地:中国大陆
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T9745ElevenostatHistone deacetylases,Elevenostat,JB3-22,multiple myeloma,inhibit,HDAC11,Inhibitor,HDAC
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235??M.
价 格:¥电议型 号:T9745产 地:中国大陆
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T6S2116Ginkgolic acid C17:1Phosphatase and tensin homolog,PTEN,Phosphatase,Inhibitor,MMAC1,inhibit,Ginkgoli
1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.
价 格:¥电议型 号:T6S2116产 地:中国大陆
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T8638NPC 15199NSC334290,NPC-15199,NPC 15199,NPC15199,Fmoc-leucine,inhibit,Inhibitor,NSC 334290,Peroxisome
NPC 15199 is an anti-inflammatory agent.
价 格:¥电议型 号:T8638产 地:中国大陆
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TN2103PROCYANIDIN C1PCC 1,inhibit,Procyanidin C 1,PROCYANIDIN C1,PCC1,PCC-1,PROCYANIDIN C-1,Inhibitor,Apop
Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.
价 格:¥电议型 号:TN2103产 地:中国大陆
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T8841IMT1NDUFB8,chain,POLRMT,DNA/RNA Synthesis,Inhibitor,OXPHOS,Mitochondrial Metabolism,citric,IMT-1,deo
Anticancer.
价 格:¥电议型 号:T8841产 地:中国大陆
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T6S2122Ginkgolic Acid (C13:0)Inhibitor,inhibit,Bacterial,Ginkgolic Acid (C-13:0),Ginkgolic Acid (C13:0)
1.Ginkgolic acid C13: 0exhibits the highest α-glucosidase inhibitory activity.
价 格:¥电议型 号:T6S2122产 地:中国大陆
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T6543IndoximodmTORC1,NLG8189,inhibit,Indoximod,tryptophan,Inhibitor,Indoleamine 2,3-Dioxygenase (IDO),Trp
Indoximod is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
价 格:¥电议型 号:T6543产 地:中国大陆