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T12824LS55746BLC201
S55746 is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM).
价 格:¥电议型 号:T12824L产 地:中国大陆
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T16392ONC206ONC206
ONC206 is an analogue of TRAIL inducer ONC201 and is a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations. ONC206 also has broad-spectrum anti-tumor activity.
价 格:¥电议型 号:T16392产 地:美洲
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T2095RoscovitineRoscovitine,CYC202,R-roscovitine
Roscovitine is a potent inhibitor of Cdk2/cyclin E (IC50: 0.1 μM). It also inhibits Cdk7/cyclin H, Cdk5/p35, and Cdc2/cyclin B (IC50s: 0.49/0.16/0.65 μM).
价 格:¥电议型 号:T2095产 地:美洲
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T2234SC-202671SC-202671,SC202671,SC 202671
TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
价 格:¥电议型 号:T2234产 地:美洲
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T2345PTC-209PTC-209,PTC209,PTC 209
PTC-209 is a potent and selective BMI-1 inhibitor.
价 格:¥电议型 号:T2345产 地:美洲
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T2585BedaquilineBedaquiline,R207910,TMC207
Bedaquiline(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.
价 格:¥电议型 号:T2585产 地:美洲
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T2640DCC-2036DCC-2036,DCC2036,DCC 2036
DCC-2036 (Rebastinib) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit.
价 格:¥电议型 号:T2640产 地:美洲
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T5341WYC209WYC209
WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).
价 格:¥电议型 号:T5341产 地:美洲
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T5642BC2059BC2059
BC2059 is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
价 格:¥电议型 号:T5642产 地:美洲
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T7647Eicosadienoic acid二十碳二烯酸二十碳二烯酸|||11,14-二十碳二烯酸C20:2
Eicosadienoic acid is a rare, natural n-6 polyunsaturated fatty acid found mainly in animal tissues.
价 格:¥电议型 号:T7647产 地:中国大陆
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T74367SC209;化合物 SC209SC209
SC209, an ADC cytotoxin is used in synthesis of anti- EGFR antibody-drug conjugate ADC. SC209 is a metabolite of STRO-002 [1] [2] .
价 格:¥电议型 号:T74367产 地:中国大陆
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T7294Aramchol;化合物AramcholC20-FABAC;C20-FABAC
Aramchol (C20-FABAC), also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholesterol crystals in a dose-dependent manner.
价 格:¥电议型 号:T7294产 地:中国大陆
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T71026MC2050 HCl;化合物 MC2050 HClMC2050 HCl
MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.
价 格:¥电议型 号:T71026产 地:中国大陆
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T7089SGC2085;化合物SGC2085SGC2085
SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).
价 格:¥电议型 号:T7089产 地:中国大陆
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T7007UNC2025化合物UNC2025mrx-6313|||UNC-2025|||UNC 2025
UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
价 格:¥电议型 号:T7007产 地:中国大陆
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T6705TIC10 Isomer;化合物TIC10 IsomerONC201 isomer|||TIC10 Analogue;ONC201 isomer|||TIC10 Analogue
TIC10 Isomer (ONC201 isomer) is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
价 格:¥电议型 号:T6705产 地:中国大陆
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T6362Domatinostat;化合物4SC2024SC202|||4SC 202|||4SC-202 (free base)|||4SC-202;4SC202|||4SC 202|||4SC-202 (f
Domatinostat (4SC202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
价 格:¥电议型 号:T6362产 地:中国大陆
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T5642Tegatrabetan;化合物BC2059BC2059;BC2059
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
价 格:¥电议型 号:T5642产 地:中国大陆
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T5341WYC-209;化合物WYC209WYC209;WYC209
WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).
价 格:¥电议型 号:T5341产 地:中国大陆
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T4419UNC2025 2HCl (1429881-91-3(free base));化合物UNC2025 2HClUNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
价 格:¥电议型 号:T4419产 地:中国大陆