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T40849C20 Ceramide;C20神经酰胺N-Arachidoyl-D-sphingosine;N-Arachidoyl-D-sphingosine
C20 Ceramide (N-Arachidoyl-D-sphingosine) is a 20:0 ceramide found in the brain that crosses the blood-brain barrier to activate microglia and induce depressive-like behavior.
价 格:¥电议型 号:T40849产 地:中国大陆
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T40452N-Acetylpsychosine;N-AcetylpsychosineN-Acetylpsychosine|||C2 Galactosylceramide (d18:1/2:0);N-Acetyl
N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties. This compound, N-Acetylpsychosine, holds potential as a valuable tool for studying the mechanisms of apoptosis and immune responses activated by dendritic cells (DCs).
价 格:¥电议型 号:T40452产 地:中国大陆
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T38946C8 Dihydroceramide;C8 DihydroceramideC8 Dihydroceramide;C8 Dihydroceramide
C8 Dihydroceramide acts as a negative control for C8 Ceramide, a cell-permeable analog of natural ceramides. C8 Ceramide, also known as N-Octanoyl-D-erythro-sphingosine, exhibits potent chemotherapeutic properties and anti-proliferation effects. Additionally, it stimulates dendritic cells to enhance T cell responses during viral infections. In vitro studies have also shown that C8 Ceramide induces a slight activation of protein kinase (PKC) [4].
价 格:¥电议型 号:T38946产 地:中国大陆
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T38284C24 dihydro 1-Deoxyceramide (m18:0/24:0);C24 dihydro 1-Deoxyceramide (m18:0/24:0)C24 dihydro 1-Deoxy
C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord,
价 格:¥电议型 号:T38284产 地:中国大陆
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T38282C22 Glucosylceramide (d18:1/22:0);C22 Glucosylceramide (d18:1/22:0)C22 Glucosylceramide (d18:1/22:0)
C22 Glucosylceramide (d18:1/22:0) is an endogenous glucosylceramide. Glucosylceramides are major constituents of skin lipid membranes where they play a role in maintaining the water permeability barrier. They are precursors in the synthesis of lactosylceramide , as well as oligoglycolipids and gangliosides. Phospholipase A2 (PLA2) type XIIA knockdown increases C22 glucosylceramide (d18:1/22:0) expression in rat brain. It is also increased in the brain, but not the liver or spinal cord, of mice f
价 格:¥电议型 号:T38282产 地:中国大陆
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T38281C22 Galactosylceramide (d18:1/22:0);C22 Galactosylceramide (d18:1/22:0)C22 Galactosylceramide (d18:1
C22 Galactosylceramide is a sphingolipid that has been found in the central nervous system.1,2C22 Galactosylceramide levels are increased in the spinal cord, but not the brain or liver, of mice fed a methionine-restricted diet.1C22 Galactosylceramide has been found in postmortem hippocampus from patients with Alzheimer´s disease.2[Matreya, LLC.]
价 格:¥电议型 号:T38281产 地:中国大陆
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T38280C22 dihydro 1-Deoxyceramide (m18:0/22:0);C22 dihydro 1-Deoxyceramide (m18:0/22:0)C22 dihydro 1-Deoxy
C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C22 dihydro 1-Deoxyceramide (m18:0/22:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found as the most prevalent dihydro
价 格:¥电议型 号:T38280产 地:中国大陆
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T38181C17 Lactosylceramide (d18:1/17:0);C17 Lactosylceramide (d18:1/17:0)C17 Lactosylceramide (d18:1/17:0)
C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue.
价 格:¥电议型 号:T38181产 地:中国大陆
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T38180C16 Phytoceramide (t18:0/16:0);C16 Phytoceramide (t18:0/16:0)C16 Phytoceramide (t18:0/16:0)
C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/16:0) is composed of a phytosphingosine backbone amine-linked to a C16 fatty acid chain. The levels of C16 phytoceramide (t18:0/16:0) increase following heat stress in S. cerevisiae. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous
价 格:¥电议型 号:T38180产 地:中国大陆
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T38048Globotetraosylceramides (porcine RBC);Globotetraosylceramides (porcine RBC)Globotetraosylceramides (
Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19. Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways. Levels of globotetraosylceramides
价 格:¥电议型 号:T38048产 地:中国大陆
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T38011C2 Adamantanyl Globotriaosylceramide (d18:1/2:0);C2 Adamantanyl Globotriaosylceramide (d18:1/2:0)C2
C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide that contains an adamantanyl group in place of the fatty acyl chain. It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 in MDCK cells. It also increases apical-to-basal transport of vinblastine in human intestinal
价 格:¥电议型 号:T38011产 地:中国大陆
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T37872C16 Galactosylceramide (d18:1/16:0);C16 Galactosylceramide (d18:1/16:0)C16 Galactosylceramide (d18:1
C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid .
价 格:¥电议型 号:T37872产 地:中国大陆
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T37565C6 D-threo Ceramide (d18:1/6:0);C6 D-threo Ceramide (d18:1/6:0)C6 D-threo Ceramide (d18:1/6:0);C6 D-
C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater
价 格:¥电议型 号:T37565产 地:中国大陆
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T37564C4 Ceramide (d18:1/4:0);C4 Ceramide (d18:1/4:0)C4 Ceramide (d18:1/4:0)|||Cer(d18:1/4:0);C4 Ceramide
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. [1] C4 Ceramide is cytotoxic to SK-BR-3 and MCF-7/Adr breast cancer cells (IC50s = 15.9 and 19.9 μM, respectively). [2] C4 Ceramide also increases maturation and stability of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing
价 格:¥电议型 号:T37564产 地:中国大陆
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T37563C22 Ceramide (d18:1/22:0);C22神经酰胺(d18:1/22:0)Cer(d18:1/22:0)|||C22 Ceramide|||Ceramide (d18:1/22:0);
C22 Ceramide (d18:1/22:0) (C22 Ceramide), a long-chain ceramide containing behenic acid, is an endogenous bioactive sphingolipid.C22-Ceramide specifically inhibits MCSR and reduces C16 ceramide channel formation in isolated rat liver mitochondria and liposomes.
价 格:¥电议型 号:T37563产 地:中国大陆
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T37562C16 Ceramide;N-棕榈酰神经鞘氨醇N-acylsphingosine|||C16 Ceramide (d18:1/16:0)|||Palmitoyl Ceramide|||N-Palmit
C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it.
价 格:¥电议型 号:T37562产 地:中国大陆
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T37458C18 Phytoceramide (t18:0/18:0);C18 Phytoceramide (t18:0/18:0)C18 Phytoceramide (t18:0/18:0)
C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TN
价 格:¥电议型 号:T37458产 地:中国大陆
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T37457C18 L-threo Ceramide (d18:1/18:0);C18 L-threo Ceramide (d18:1/18:0)C18 L-threo Ceramide (d18:1/18:0)
C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids. It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.21 mol% (16.8 μM).
价 格:¥电议型 号:T37457产 地:中国大陆
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T37456C18 L-erythro Ceramide (d18:1/18:0);C18 L-erythro Ceramide (d18:1/18:0)C18 L-erythro Ceramide (d18:1
C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide . It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.11 mol% (8.8 μM).
价 格:¥电议型 号:T37456产 地:中国大陆
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T37455C18 D-threo Ceramide (d18:1/18:0);C18 D-threo Ceramide (d18:1/18:0)C18 D-threo Ceramide (d18:1/18:0)
C18 D-threoCeramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50value of 16.6 μM.2
价 格:¥电议型 号:T37455产 地:中国大陆