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T78950HIV-1 protease-IN-8;化合物 HIV-1 protease-IN-8HIV-1 protease-IN-8
HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM. It demonstrates IC50 values of 0.29 μM for the wild-type HIV-1 (HIV-1 NL4-3) and 1.90 μM against a drug-resistant variant (HIV-1 MDR), indicating strong antiviral activity against both strains [1].
价 格:¥电议型 号:T78950产 地:中国大陆
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T78925HIV-1 inhibitor-58;化合物 HIV-1 inhibitor-58HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type strain IIIB and NNRTI-resistant strains like K103N and E138K in MT-4 cells at an EC50 of less than 50 nM. Additionally, it inhibits CYP2C9 and CYP2C19 with IC50 values of 2.06 μM and 1.91 μM, respectively. This compound is utilized in HIV infection research [1].
价 格:¥电议型 号:T78925产 地:中国大陆
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T78749HIV-1 inhibitor-57;化合物 HIV-1 inhibitor-57HIV-1 inhibitor-57
HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficacy by forming supplementary interactions with residues surrounding the binding site in the HIV-1 reverse transcriptase (RT) [1].
价 格:¥电议型 号:T78749产 地:中国大陆
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T76537GP120, HIV-1 MN;化合物 GP120, HIV-1 MNGP120, HIV-1 MN
GP120, HIV-1 MN, a peptide, is utilized in researching HIV infection [1] [2].
价 格:¥电议型 号:T76537产 地:中国大陆
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T76502HIV-1, HIV-2 Protease Substrate;化合物 HIV-1, HIV-2 Protease SubstrateHIV-1, HIV-2 Protease Substrate
HIV-1, HIV-2 Protease Substrate is a compound serving as the substrate for the proteases of both HIV-1 and HIV-2, featuring four residues that allow for conservative substitutions at the substrate binding sites of these enzymes [1].
价 格:¥电议型 号:T76502产 地:中国大陆
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T75964HIV-1 TAT (48-60);化合物 HIV-1 TAT (48-60)HIV-1 TAT (48-60)
HIV-1 TAT (48-60), a cell-penetrating peptide originating from residues 48-60 of the human immunodeficiency virus (HIV)-1 Tat protein, facilitates the non-disruptive delivery of exogenous macromolecules into cells.
价 格:¥电议型 号:T75964产 地:中国大陆
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T74942HIV-1 protease-IN-7;化合物 HIV-1 protease-IN-7HIV-1 protease-IN-7
HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].
价 格:¥电议型 号:T74942产 地:中国大陆
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T74488HIV-1 protease-IN-4;化合物 HIV-1 protease-IN-4HIV-1 protease-IN-4
HIV-1 protease-IN-4 (Compound II-22), a potent inhibitor of the HIV-1 protease, acts as a prodrug for atazanavir. It notably enhances the bioavailability of atazanavir in rat plasma, achieving a 5-fold increase in the area under the curve (AUC) and a 67-fold increase in concentration at 24 hours (C24) compared to oral administration of atazanavir alone [1].
价 格:¥电议型 号:T74488产 地:中国大陆
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T74211HIV-1 inhibitor-12;化合物 HIV-1 inhibitor-12HIV-1 inhibitor-12
HIV-1 inhibitor-12 is a potent inhibitor that targets the HIV-1 capsid protein, effectively preventing its polymerization with an inhibition concentration (IC 50) of 9 nM.
价 格:¥电议型 号:T74211产 地:中国大陆
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T74210HIV-1 inhibitor-11;化合物 HIV-1 inhibitor-11HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.
价 格:¥电议型 号:T74210产 地:中国大陆
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T72582HIV-1 inhibitor-48;化合物 HIV-1 inhibitor-48HIV-1 inhibitor-48
HIV-1 inhibitor-48 is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity [1] .
价 格:¥电议型 号:T72582产 地:中国大陆
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T72568HIV-1 inhibitor-53;化合物 HIV-1 inhibitor-53HIV-1 inhibitor-53
HIV-1 Inhibitor-53 is a dual inhibitor targeting both the HIV-1 protease (PR) with an IC50 value of 1.93 nM and reverse transcriptase (RT) with an IC50 of 2.35 μM. It serves as a potent agent for AIDS research [1].
价 格:¥电议型 号:T72568产 地:中国大陆
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T72566HIV-1 inhibitor-50;化合物 HIV-1 inhibitor-50HIV-1 inhibitor-50
HIV-1 inhibitor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (IC50 = 50 nM). HIV-1 inhibitor-50 shows significant antiviral activity, with EC50s of 2.22-53.3nM against HIV-1 IIIB and its mutant strains.
价 格:¥电议型 号:T72566产 地:中国大陆
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T72565HIV-1 inhibitor-52;化合物 HIV-1 inhibitor-52HIV-1 inhibitor-52
HIV-1 inhibitor-52 is a powerful inhibitor of a broad spectrum of HIV-1 activities, demonstrating effectiveness with EC50 values ranging from 1.6 nM to 6.4 nM against various strains, including WT HIV-1, HIV-1 V370A, HIV-1 ΔV370, HIV-1 V362I/V370A, HIV-1 T332S/V362I/prR41G, HIV-1 A326T/V362I/V370A, and HIV-1 R361K/V362I/L363M.
价 格:¥电议型 号:T72565产 地:中国大陆
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T72563HIV-1 inhibitor-49;化合物 HIV-1 inhibitor-49HIV-1 inhibitor-49
HIV-1 Inhibitor-49, a HEPT analog, is an orally active non-nucleoside reverse transcriptase inhibitor with potent activity against HIV-1, demonstrating an IC 50 of 30 nM. It features an excellent pharmacokinetic profile and has shown to be potentially safe without acute toxicity in mouse models.
价 格:¥电议型 号:T72563产 地:中国大陆
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T72534HIV-1 inhibitor-10;化合物 HIV-1 inhibitor-10HIV-1 inhibitor-10
HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.
价 格:¥电议型 号:T72534产 地:中国大陆
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T72162HIV-1 integrase inhibitor 10;化合物 HIV-1 integrase inhibitor 10HIV-1 integrase inhibitor 10
HIV-1 Integrase Inhibitor 10, an orally active allosteric integrase inhibitor (ALLINI), effectively inhibits the NLRepRluc virus´s viral outgrowth in MT-2 cells, exhibiting EC50 values of 3-5 nM. This compound is utilized in the research of Human Immunodeficiency Virus-1 (HIV-1).
价 格:¥电议型 号:T72162产 地:中国大陆
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T67833HIV-1 inhibitor-54;HIV-1 抑制剂54HIV-1 inhibitor-54
HIV-1 inhibitor-54 is a potent HIV-1 inhibitor showing anti-HIV activity (EC50 : 32 nM) against WT HIV-1 (strain IIIB) x in MT-4 cells.HIV-1 inhibitor-54 can be used to study viral infections.
价 格:¥电议型 号:T67833产 地:中国大陆
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T64131HIV-1 inhibitor-17;化合物 HIV-1 inhibitor-17HIV-1 inhibitor-17
HIV-1 inhibitor-18 is a potent inhibitor of the HIV-1 capsid and is able to act on the HIV-1 NL4-3 strain (EC50: 2.57 μM). HIV-1 inhibitor-18 exhibits some cytotoxicity with an MT-4CC50 value of >8.55.
价 格:¥电议型 号:T64131产 地:中国大陆
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T64112HIV-1 protease-IN-5;化合物 HIV-1 protease-IN-5HIV-1 protease-IN-5
HIV-1 protease-IN-5 is an HIV-1 protease inhibitor (IC50: 1.64 nM). HIV-1 protease-IN-5 exhibits significant effects on wild-type and DRV-resistant HIV-1.
价 格:¥电议型 号:T64112产 地:中国大陆