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  • T62431HIV-1 inhibitor-25；化合物 HIV-1 inhibitor-25HIV-1 inhibitor-25

    HIV-1 inhibitor-25 (compound R-12a) is a potent inhibitor of HIV-1 reverse transcription (HIV-1 RT) (IC50: 0.1061 nM). HIV-1 inhibitor-25 exhibits a high antiviral effect against wild-type HIV-1 with an EC50 value of 13.6 nM and a low cytotoxicity (to MT). HIV-1 inhibitor-25 also inhibits HIV-1 mutants (L100I, K103 N, Y181C, Y188L, E138K, F227L+V106A) with EC50=0.1961 ~ 5.8136 μM. inhibitor-25 can be used to study AIDS.

    价 格：￥电议型 号：T62431产 地：中国大陆

  • T62430HIV-1 inhibitor-24；化合物 HIV-1 inhibitor-24HIV-1 inhibitor-24

    HIV-1 inhibitor-24 (compound S-12a) is a potent inhibitor of HIV-1 reverse transcription (HIV-1 RT) (IC50: 9.5 nM). HIV-1 inhibitor-24 exhibits a high antiviral effect on wild-type HIV-1 with an EC50 value of 1.6 nM and low cytotoxicity (CC50 on MT-4 cells). HIV-1 inhibitor-24 was well tolerated in mice at a dose of 2 g/kg and had a significant cardiovascular safety profile.

    价 格：￥电议型 号：T62430产 地：中国大陆

  • T62353HIV-1 inhibitor-33；化合物 HIV-1 inhibitor-33HIV-1 inhibitor-33

    HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor that acts on HIV-1 (EC50: 8.6 nM), MT-4 cells (CC50: 18 μM). HIV-1 inhibitor-33 can be used in the study of AIDS.

    价 格：￥电议型 号：T62353产 地：中国大陆

  • T62319HIV-1 inhibitor-44；化合物 HIV-1 inhibitor-44HIV-1 inhibitor-44

    HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).

    价 格：￥电议型 号：T62319产 地：中国大陆

  • T62287HIV-1 inhibitor-42；化合物 HIV-1 inhibitor-42HIV-1 inhibitor-42

    HIV-1 inhibitor-42 (compound 5b) is a potent inhibitor of HIV-1 (IC50: 0.06 μM). HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase (IC50: 0.518 μM) and DNA-dependent DNA polymerase (IC50. 0.072 μM).

    价 格：￥电议型 号：T62287产 地：中国大陆

  • T62156HIV-1 integrase inhibitor 9；化合物 HIV-1 integrase inhibitor 9HIV-1 integrase inhibitor 9

    HIV-1 integrase inhibitor 9 (compound 8a) is a potent inhibitor of HIV-1 RNase H (IC50: 12.3 μM) and has antiviral effects.

    价 格：￥电议型 号：T62156产 地：中国大陆

  • T62129HIV-1 inhibitor-16；化合物 HIV-1 inhibitor-16HIV-1 inhibitor-16

    HIV-1 inhibitor-16 (compound 7a) is a potent HIV-1 inhibitor with an EC50 of 1.3 nM against wild-type HIV-1. HIV-1 inhibitor-16 also showed some inhibitory activity against HIV-1 K103N, E138K, Y181C and L100I strains with EC50s of 5.4 nM, 9.2 nM, 22 nM and 35 nM, respectively. HIV-1 inhibitor-16 showed good solubility and hepatic microsomal stability and did not exhibit significant CYP enzyme inhibitory activity or acute toxicity.

    价 格：￥电议型 号：T62129产 地：中国大陆

  • T62070HIV-1 inhibitor-31；化合物 HIV-1 inhibitor-31HIV-1 inhibitor-31

    HIV-1 inhibitor-31 (compound 4) is a potent inhibitor of HIV-1. HIV-1 inhibitor-31 can be used in the study of AIDS.

    价 格：￥电议型 号：T62070产 地：中国大陆

  • T62010HIV-1 inhibitor-20；化合物 HIV-1 inhibitor-20HIV-1 inhibitor-20

    HIV-1 inhibitor-20 is a potent HIV-1 inhibitor.

    价 格：￥电议型 号：T62010产 地：中国大陆

  • T61844HIV-1 inhibitor-9；化合物 HIV-1 inhibitor-9HIV-1 inhibitor-9

    HIV-1 inhibitor-9 exhibits potent inhibition activity at low nanomolar concentrations against both the wild-type (WT) HIV-1 strain and multiple strains that have developed resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs).

    价 格：￥电议型 号：T61844产 地：中国大陆

  • T61801HIV-1 inhibitor-35；化合物 HIV-1 inhibitor-35HIV-1 inhibitor-35

    HIV-1 inhibitor-35 (compound 74) is a highly potent inhibitor of the HIV-1 virus, exhibiting EC50 values of 80 nM and 70 nM for LTR and CMV, respectively, in HEK293 cells. Additionally, HIV-1 inhibitor-35 demonstrates inhibitory activity against HepG2 liver cancer cells, with a CC50 value of 40 nM. Moreover, HIV-1 inhibitor-35 shows promise as a potential HIV-1 latency reversing agent [1].

    价 格：￥电议型 号：T61801产 地：中国大陆

  • T61797HIV-1 inhibitor-15；化合物 HIV-1 inhibitor-15HIV-1 inhibitor-15

    HIV-1 inhibitor-15 (compound 9d) is a potent and broad-spectrum inhibitor targeting HIV-1. It exhibits inhibitory activity against HIV-1 WT, L100I, K103N, Y181C, and E138K with respective EC50 values of 1.7 nM, 4 nM, 2 nM, 6 nM, and 9 nM. In addition to its high efficacy, HIV-1 inhibitor-15 possesses favorable solubility, safety profiles, and oral bioavailability [1].

    价 格：￥电议型 号：T61797产 地：中国大陆

  • T61670HIV-1 inhibitor-38；化合物 HIV-1 inhibitor-38HIV-1 inhibitor-38

    HIV-1 inhibitor-38 (Compound 91) is a powerful agent that inhibits the activity of HIV-1. It exhibits great potential as a novel latency reversing agent, making it a promising candidate for further development [1].

    价 格：￥电议型 号：T61670产 地：中国大陆

  • T61311HIV-1 inhibitor-30；化合物 HIV-1 inhibitor-30HIV-1 inhibitor-30

    HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM. Furthermore, HIV-1 inhibitor-30 demonstrates significant effectiveness against seven NNRTI-resistant strains of HIV-1 (RT-K103N; RT-Y181C; RT-K103N, Y181C; RT-L100I, K103N; RT-Y188L; RT-K103N, G190A; RT-K103N, V108I), with IC 50 values ranging from 0.04 to 1.42 μM. This compound

    价 格：￥电议型 号：T61311产 地：中国大陆

  • T61310HIV-1 inhibitor-37；化合物 HIV-1 inhibitor-37HIV-1 inhibitor-37

    HIV-1 inhibitor-37 (Compound 83) is a highly powerful HIV-1 inhibitor. It exhibits significant potential for use as an innovative latent HIV-1 reactivating agent [1].

    价 格：￥电议型 号：T61310产 地：中国大陆

  • T61134HIV-1 inhibitor-36；化合物 HIV-1 inhibitor-36HIV-1 inhibitor-36

    HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1 inhibitor with significant potential as a novel latency reversing agent [1].

    价 格：￥电议型 号：T61134产 地：中国大陆

  • T61031HIV-1 inhibitor-41；化合物 HIV-1 inhibitor-41HIV-1 inhibitor-41

    HIV-1 inhibitor-41 (Compound B23) is an orally active inhibitor of non-nucleoside HIV-1 reverse transcriptase with EC 50 values of 50 nM and 20.8 nM against mutant E138K strain and HIV-1 WT, respectively. HIV-1 inhibitor-41 exhibits low hERG inhibition, no apparent CYP enzymatic inhibition as well as no acute toxicity [1].

    价 格：￥电议型 号：T61031产 地：中国大陆

  • T60742HIV-1 integrase inhibitor 8；HIV-1整合酶抑制剂8HIV-1 integrase inhibitor 8

    HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].

    价 格：￥电议型 号：T60742产 地：中国大陆

  • T60342HIV-1 inhibitor-47；化合物 HIV-1 inhibitor-47HIV-1 inhibitor-47

    HIV-1 inhibitor-47 is a compound that effectively inhibits HIV-1 by preventing the vif-dependent degradation of human APOBEC3G. It has a notable inhibition effect, with an IC50 value of 14.33 μM. Additionally, HIV-1 inhibitor-47 is involved in the synthesis of derivatives of 1-(2-pyrimidinyl)piperazine, which have the potential to exhibit antianxiety, antidepressant, and antipsychotic effects [1] [2] [3].

    价 格：￥电议型 号：T60342产 地：中国大陆

  • T40719(Cys47)-HIV-1 tat Protein (47-57)；(Cys47)-HIV-1 tat Protein (47-57)(Cys47)-HIV-1 tat Protein (47-57)

    (Cys47)-HIV-1 tat Protein (47-57) possesses membrane translocation functionality and can serve as a surface derivatization agent for magnetic pharmaceuticals, thereby enhancing their uptake into specific target cells.

    价 格：￥电议型 号：T40719产 地：中国大陆

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