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T9399Menin-MLL inhibitor 20Epigenetic Reader Domain,mixed-lineage,MeninMLL inhibitor 20,irreversible,leuk
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities (WO2020142557A1, compound 6).
价 格:¥电议型 号:T9399产 地:中国大陆
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T7392RevefenacinRevefenacin,TD4208,TD 4208,inhibit,Muscarinic acetylcholine receptor,Inhibitor,mAChR,GSK
Revefenacin is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.
价 格:¥电议型 号:T7392产 地:中国大陆
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T3242BreviscapinBreviscapin
Breviscapine is the total flavonoid components (the content of scutellarin > or =85%) extracted from the dried whole plant of Erigeron breviscapus.
价 格:¥电议型 号:T3242产 地:中国大陆
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T6519GramineGramine,Adrenergic Receptor,AdipoRs,Reverse Transcriptase,Inhibitor,Adiponectin Receptor,Beta
Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist. Gramine has anti-tumor, anti-viral and anti-inflammatory properties.
价 格:¥电议型 号:T6519产 地:中国大陆
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T9854HIV-1 inhibitor-6?pre-mRNA alternative splicing,HIV-1IIIB,inhibit,Inhibitor,HIV1 inhibitor6?,reverse
3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo- is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.
价 格:¥电议型 号:T9854产 地:中国大陆
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T6190TelaprevirLY-570310;Incivek;MP-424;VX-950;特拉匹韦
Telaprevir (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
价 格:¥电议型 号:T6190产 地:中国大陆
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T6025Danoprevir丹诺普韦;R7227;ITMN-191;RO5190591;RG7227
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).
价 格:¥电议型 号:T6025产 地:中国大陆
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T5126GlecaprevirABT-493
Glecaprevir is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).
价 格:¥电议型 号:T5126产 地:中国大陆
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T4988Boceprevir波普瑞韦;SCH 503034;EBP 520
Boceprevir is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-based replicon assay.
价 格:¥电议型 号:T4988产 地:中国大陆
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T4686Simeprevir西咪匹韦;TMC-435350;TMC435
Simeprevir is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.
价 格:¥电议型 号:T4686产 地:中国大陆
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T4672Brevilin A
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAK
价 格:¥电议型 号:T4672产 地:中国大陆
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T4547GrazoprevirMK-5172
MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), 0.15 nM (gt2b), respectively.
价 格:¥电议型 号:T4547产 地:中国大陆
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T4474Asunaprevir阿那匹韦;BMS-650032
Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
价 格:¥电议型 号:T4474产 地:中国大陆
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T3996Dapiprazole Hydrochloride盐酸达哌唑;Glamidolo Hydrochloride;Reversil Hydrochloride
Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.
价 格:¥电议型 号:T3996产 地:中国大陆
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T37596Terevalefim
Terevalefim (ANG-3777), an hepatocyte growth factor (HGF) mimetic, selectively activates the c-Met receptor[1][2].
价 格:¥电议型 号:T37596产 地:中国大陆
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T3685SR9009Stenabolic;REV-ERB Agonist II
SR9009, a REV-ERB agonist, increases the constitutive repression of genes regulated by REV-ERBα/ERBβ (IC50: 670/800 nM). Through activation of REV-ERB, SR9009 can decrease circadian locomotor activity during the dark phase and alter the expression pattern
价 格:¥电议型 号:T3685产 地:中国大陆
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T3208Brevianamide Fcyclo-(L-Trp-L-Pro);Cyclo-L-tryptophyl-L-proline;Cyclo(L-Pro-L-Trp)
Brevianamide F, also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess interesting breast cancer resistance protein inhibitory activity.
价 格:¥电议型 号:T3208产 地:中国大陆
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T3156Ciliobrevin AHPI-4;Hedgehog Pathway Inhibitor 4
Ciliobrevin A is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM.
价 格:¥电议型 号:T3156产 地:中国大陆
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T2789Scutellarin黄岑素;野黄芩苷;Breviscapin;Breviscapinun;Scutellarein-7-glucuronide;Breviscapine
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Girdin/Akt signaling in HCC cells.
价 格:¥电议型 号:T2789产 地:中国大陆
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T2405Revaprazan hydrochloride盐酸瑞伐拉赞;YH1885
Revaprazan Hydrochloride is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.
价 格:¥电议型 号:T2405产 地:中国大陆