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T38918Revusiran;RevusiranALN-TTRSC;ALN-TTRSC
Revusiran (ALN-TTRSC) is a first-generation short interfering RNA (siRNA) that specifically targets transthyretin (TTR) mRNA. It is utilized in TTR-mediated amyloidosis research.
价 格:¥电议型 号:T38918产 地:中国大陆
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T38849Idrevloride;IdrevlorideIdrevloride
Idrevloride is a chemical compound (WO2016133967) known for its effective inhibition of epithelial sodium channels (ENaC). Its application extends to the research of various skin disorders.
价 格:¥电议型 号:T38849产 地:中国大陆
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T38553Previtamin D3;Previtamin D3Previtamin D3;Previtamin D3
Previtamin D3 is an intermediate in the production of cholecalciferol (vitamin D3).
价 格:¥电议型 号:T38553产 地:中国大陆
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T38044Reveromycin B;Reveromycin BReveromycin B
Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells (IC50 = 6 μg/ml) and exhibits pH-dependent antifungal activity against C. albicans (MICs = 15.6 and >500 μg/ml at pH 3.0 and 7.4, respectively). Unlike reveromycin A and reveromycin C , reveromycin B does not inhibit proliferation of KB and K562 cells.
价 格:¥电议型 号:T38044产 地:中国大陆
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T37596Terevalefim;化合物TerevalefimTerevalefim
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
价 格:¥电议型 号:T37596产 地:中国大陆
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T37426FIIN-1;化合物FIIN-1FGFR irreversible inhibitor-1;FGFR irreversible inhibitor-1
FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3, FGFR4, Flt1, Flt14, respectively.FIIN-1 inhibited FGFR1, FGFR2, FGFR3, FGFR4, with IC50 of 9.2, 6.2, 11.9 and 189 nM. FIIN-1 inhibited FGFR1, FGFR2, FGFR3 and FGFR4, with IC50s of 9.2, 6.2, 11.9 and 189 nM, respectively.
价 格:¥电议型 号:T37426产 地:中国大陆
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T37423Reveromycin D;Reveromycin DReveromycin D
Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μg/ml at pH 3 and 7.4, respectively). Reveromycin D also inhibits proliferation of KB and K562 cells (IC50s = 1.6 and 1.3 μg/ml, respectively).
价 格:¥电议型 号:T37423产 地:中国大陆
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T37008Reveromycin A;雷弗霉素AReveromycin A
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antiproliferative activity against human KB and K562 tumor cell lines (IC50s = 1.9 and 1.6 μg/ml, respectively), and demonstrates antifungal activity against C. albicans (MIC = 2 μg/ml at pH 3). Reveromycin A also has been shown to inhibit bone resorption by inducing apoptosis in oste
价 格:¥电议型 号:T37008产 地:中国大陆
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T37006Previridicatumtoxin;PreviridicatumtoxinPreviridicatumtoxin
Previridicatumtoxin is a fungal metabolite that has been found inP. aethiopicumand has diverse biological activities.1,2It is an intermediate in the biosynthesis of the mycotoxin viridicatumtoxin . Previridicatumtoxin is active against methicillin-resistantS. aureus(MRSA) and vancomycin-resistantE. faecalis(IC50s = 4.4 and 4.8 μM, respectively), as well asC. albicansandS. cerevisiae(MIC = 32 μg/ml for both).2,1It is cytotoxic to NCI H460, KB-3-1, and SW620 cancer cells (IC50s = 5.3, 4.1, and 6 μ
价 格:¥电议型 号:T37006产 地:中国大陆
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T3685SR9009;化合物SR9009Stenabolic|||REV-ERB Agonist II;Stenabolic|||REV-ERB Agonist II
SR9009 (Stenabolic), a REV-ERB agonist, increases the constitutive repression of genes regulated by REV-ERBα/ERBβ (IC50: 670/800 nM). Through activation of REV-ERB, SR9009 can decrease circadian locomotor activity during the dark phase and alter the expression pattern of core clock genes in the hypothalami of mice. The circadian pattern of expression of an array of metabolic genes in the liver, skeletal muscle, and adipose tissue was also altered in mice exposed to SR9009, resulting in increased
价 格:¥电议型 号:T3685产 地:中国大陆
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T36734Methyl brevifolincarboxylate;Methyl brevifolincarboxylateMethyl brevifolincarboxylate
Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico/8/34 (H1N1) and A/Aichi/2/68 (H3N2) with IC50s of 27.16 μM and 33.41 μM. Anti-oxidant activity[1][2].
价 格:¥电议型 号:T36734产 地:中国大陆
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T36068Brevetoxin B;Brevetoxin BBrevetoxin B
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.
价 格:¥电议型 号:T36068产 地:中国大陆
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T35337TeduglutideTeduglutideALX-0600|||Revestive|||TAK 633|||Gattex
Teduglutide (ALX-0600, Gattex, Revestive, TAK 633)是人胰高血糖素样肽-2 (GLP-2)的类似物,可与GLP-2 receptors 结合。Teduglutide 在动物模型中可延长 GLP-2 的肠道营养特性。
价 格:¥电议型 号:T35337产 地:中国大陆
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T35043Vedroprevir;化合物 T35043GS9451|||GS 9451|||GS-9451;GS9451|||GS 9451|||GS-9451
Vedroprevir, also known as GS9451, is a selective hepatitis C virus (HCV) NS3 protease inhibitor in the development of the treatment of genotype 1 (GT1) HCV infection.
价 格:¥电议型 号:T35043产 地:中国大陆
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T34753Suxamethonium bromide;化合物 T34753L.T. 1|||370 I.S.|||Brevidil M;L.T. 1|||370 I.S.|||Brevidil M
Suxamethonium bromide can be used to cause short-term paralysis as part of general anesthesia.
价 格:¥电议型 号:T34753产 地:中国大陆
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T34307Revenast;化合物 T34307Revenast
Revenast is a potent new anti-allergic compound. The substance is rapidly and extensively metabolized in the body, resulting in an anti-allergic effect.
价 格:¥电议型 号:T34307产 地:中国大陆
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T34146Propanidid;丙泮尼地FBA 1420|||Epontol|||Sombrevin|||Fabontal|||Fabantol;FBA 1420|||Epontol|||Sombrevin||
Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and a fast-acting intravenous anesthetic that lowers arterial blood pressure.
价 格:¥电议型 号:T34146产 地:中国大陆
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T34075Piprocurarium iodide;化合物 T34075Brevicurarine|||LD2480|||LD 2480|||LD-2480;Brevicurarine|||LD2480|||L
Piprocurarium iodide is a bioactive chemical.
价 格:¥电议型 号:T34075产 地:中国大陆
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T33624Neceprevir;化合物 T33624Deldeprevir;Deldeprevir
Neceprevir is a potential treatment for Hepatitis C.
价 格:¥电议型 号:T33624产 地:中国大陆
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T3242Breviscapin;红盏花素Scutellarin|||Scutellarin B;Scutellarin|||红盏花素|||Scutellarin B
Breviscapin (Scutellarin)e is the total flavonoid components (the content of scutellarin > or =85%) extracted from the dried whole plant of Erigeron breviscapus.
价 格:¥电议型 号:T3242产 地:中国大陆