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产品数:86101
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TN1037GroenlandicineTopoisomerase,Groenlandicine,inhibit,Inhibitor
Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage;Groenlandicine may be a promising anti-Alzheimer´s disease agent due to its potent inhibitory activity of both ChEs and beta-amyloids formation, as well as marked ONOO(-) scavenging and good ROS inhibitory capacities.
价 格:¥电议型 号:TN1037产 地:中国大陆
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T6800CCF642calcium,Inhibitor,PDI,CCF642,apoptosis,isomerases,disulfide,myeloma,CCF-642,protein,multiple,r
CCF642 is a novel PDI-inhibiting compound with antimyeloma activity.
价 格:¥电议型 号:T6800产 地:中国大陆
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T8806FluzoparibSHR 3162,homologous recombination repair,Inhibitor,poly ADP ribose polymerase,Fluzoparib,i
fluzoparib is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.
价 格:¥电议型 号:T8806产 地:中国大陆
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TN7077Sinocrassoside C1Sinocrassoside C1,Sinocrassoside C-1
Sinocrassoside C1 is the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new flavonol glycosides
价 格:¥电议型 号:TN7077产 地:中国大陆
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T6390Anagrelide hydrochloridePhosphodiesterase (PDE),Anagrelide,inhibit,Inhibitor,Anagrelide hydrochlorid
Anagrelide Hydrochloride(BL4162A) is a drug used for the treatment of essential thrombocytosis.
价 格:¥电议型 号:T6390产 地:中国大陆
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T6584MG 149HAT,Inhibitor,MG 149,Epigenetic Reader Domain,Apoptosis,HATs,inhibit,Histone Acetyltransferase
MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
价 格:¥电议型 号:T6584产 地:中国大陆
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T6781BenzenesulfonamideInhibitor,inhibit,QSAR study,Benzenesulfonamide,carbonic anhydrases,Carbonic Anhyd
Benzenesulfonamide ia an inhibitor of carbonic anhydrases.
价 格:¥电议型 号:T6781产 地:中国大陆
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T7093RafoxanideHemonchus,Rafoxanide,energy metabolism,inhibit,antiparasitic,Parasite,Fasciola,Estrus ovis
Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
价 格:¥电议型 号:T7093产 地:中国大陆
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TWS2045Bruceine DParasite,Notch,Apoptosis,Bruceine D,Inhibitor,inhibit
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW199 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
价 格:¥电议型 号:TWS2045产 地:中国大陆
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T9584UNC6934Inhibitor,UNC6934,Histone Methyltransferase,inhibit,UNC 6934,UNC-6934
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
价 格:¥电议型 号:T9584产 地:中国大陆
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T6S2024Harpagideinhibit,Harpagide,Inhibitor,Parasite
1. Harpagide has antibacterial activity. 2. Harpagide has antiviral activity. 3. Harpagide has anti-inflammatory activity.
价 格:¥电议型 号:T6S2024产 地:中国大陆
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T6566Levobupivacaine hydrochlorideCNS toxicity,gastric cancer,Na channels,Erastin,Inhibitor,analgesic,ana
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic.
价 格:¥电议型 号:T6566产 地:中国大陆
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T6S0139Neobavaisoflavoneflavonoid,corylifolia,Neobavaisoflavone,anti-oxidation,polymerase,Apoptosis,anti-ca
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can significantly inhibit the production of reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokines: IL-1β, IL-6, IL-12p4, IL-12p7, TNF-α in LPS+IFN-γ- or PMA- stimulated RAW264.7 macrophages.
价 格:¥电议型 号:T6S0139产 地:中国大陆
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T7605Avermectin B1aAntibiotic,Parasite,Inhibitor,Avermectin B-1a,inhibit,Avermectin B1a
Avermectin B1a is a macrocyclic lactone disaccharide anthelmintic agent .
价 格:¥电议型 号:T7605产 地:中国大陆
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T8344CPTH2CPTH2,histone,Histone Acetyltransferase,Inhibitor,acetyltransferase,ccRCC,HAT,Gcn5p,CPTH 2,KAT3
CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.
价 格:¥电议型 号:T8344产 地:中国大陆
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T9891PARP1-IN-8?poly ADP ribose polymerase,phthalazinone,PARP,inhibit,HFF cells,Lung adenocarcinoma,Inhib
PARP1-IN-8 is an effective inhibito of PARP1 (IC50 = 97 nM).
价 格:¥电议型 号:T9891产 地:中国大陆
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T6967RHPS4HT29,RHPS 4,Telomerase,RHPS-4,breast,Apoptosis,cancer,Inhibitor,inhibit,M14,RHPS4,PC3,H460,H2AX
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
价 格:¥电议型 号:T6967产 地:中国大陆
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TN6730EpoxyazadiradionehuMIF,Parasite,Inhibitor,proinflammatory,MIF,limonoid,inhibit,Epoxyazadiradione,par
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells.
价 格:¥电议型 号:TN6730产 地:中国大陆
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T8684SotorasibAMG 510,Ras,KRAS,covalent,Sotorasib,regression,mutation,Inhibitor,G12C,anti-tumour,inhibit,
AMG-510 is a selective and orally bioavailable KRAS G12C covalent inhibitor.
价 格:¥电议型 号:T8684产 地:中国大陆
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T9054RO6889678inhibit,Hepatitis B virus,coregulated protein,UDP-glucuronosyltransferase,HB capsid formati
RO6889678 is HBV inhibitor with a complex ADME profile.
价 格:¥电议型 号:T9054产 地:中国大陆