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产品数：86101
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TP1263Fz7-21lipid-binding groove,FZD7,Wnt,Fz7 21,Wnt–β-catenin,Fz-7-21,conformation,FZD7 CRD,intestinal or
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
价 格：￥电议型 号：TP1263产 地：中国大陆
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T6828ZL0420inhibit,Epigenetic Reader Domain,(E/Z)-ZL0420,BRD4,airway inflammation,immune response genes,Z
ZL0420 is a potent and selective bromodomain-containing protein 4 ( BRD4 ) inhibitor with nanomolar binding affinities to bromodomains (BDs) of BRD4. ZL0420 has IC 50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2.
价 格：￥电议型 号：T6828产 地：中国大陆
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TN2283Tripterifordininhibit,HIV,Human immunodeficiency virus,replication,Tripterifordin,anti-HIV,Inhibitor
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
价 格：￥电议型 号：TN2283产 地：中国大陆
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T13456(S)-Willardiine
(S)-Willardiine is present in the seeds of Acacia and Mimosa. (S)-Willardiine is an AMPA/kainate receptor agonist (EC50 = 44.8 μM).
价 格：￥电议型 号：T13456产 地：中国大陆
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T61318BRD4 Inhibitor-20
BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity. BRD4 Inhibitor-20 has antiproliferative activity in cancer cell lines and is used in studies of various cancers, such as colon cancer.
价 格：￥电议型 号：T61318产 地：中国大陆
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TN2054Periplocymarinproliferation,inhibit,Inhibitor,cardiac,Periplocymarin,U937,anti-cancer,HCT-8,cells,gl
Periplocymarin, a cardiac glycoside, has potential anti-cancer activity.
价 格：￥电议型 号：TN2054产 地：中国大陆
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T8233BRD3308β-cells,glucolipotoxicity,inflammatory,BRD-3308,Human immunodeficiency virus,BRD3308,Histone
BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.
价 格：￥电议型 号：T8233产 地：中国大陆
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T6389Anacardic AcidBacterial,HATs,inhibit,HAT,Anacardic Acid,Histone Acetyltransferase,Ginkgolic Acid C15
Anacardic Acid is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostaglandin synthase, lipoxygenase, and tyrosinase.
价 格：￥电议型 号：T6389产 地：中国大陆
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T6461Dapoxetine hydrochlorideBenign,BPH,serotonin reuptake,SERT,sexual disorder,LY210448,SLC6A4,Dapoxetin
Dapoxetine HCl is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
价 格：￥电议型 号：T6461产 地：中国大陆
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T7378BRD9539Histone Methyltransferase,chromatin,PRC2,BRD9539,G9a,senescent,BRD-9539,BRD 9539,inhibit,H3K9
BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μM
价 格：￥电议型 号：T7378产 地：中国大陆
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T7165Basmisanilα subunit-containing GABAA receptors (GABAAα5),RO-5186582,RG-1662,psychiatric disorders,ne
Basmisanil is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of cognitive impairments associated with Down syndrome.
价 格：￥电议型 号：T7165产 地：中国大陆
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T9568SGC-SMARCA-BRDVIIIEpigenetic Reader Domain,adipogenesis,SMARCA2/4,inhibit,PB1,SGCSMARCABRDVIII,Inhib
SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.
价 格：￥电议型 号：T9568产 地：中国大陆
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TQ0046BavisantJNJ31001074,JNJ 31001074,Neurological disorders,inhibit,Histamine Receptor,attention-deficit
Bavisant is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.
价 格：￥电议型 号：TQ0046产 地：中国大陆
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T8158Tilianinantioxidant,Inhibitor,inflammatory,myocardial-protective,diabetic,hyperlipidemic,inhibit,Til
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.
价 格：￥电议型 号：T8158产 地：中国大陆
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TN3594Cardanol (C15:1)Cardanol (C15:1),inhibit,Cardanol monoene,Cardanol (C-15:1),Inhibitor,Apoptosis,Card
Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells.
价 格：￥电议型 号：TN3594产 地：中国大陆
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T6086Clopamidecardiac,diuretic,Na+ channels,Na channels,inhibit,Sodium Channel,Clopamide,thiazide-like,an
Clopamide is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.
价 格：￥电议型 号：T6086产 地：中国大陆
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T6636RefametinibMEK1,allosteric,RDEA 119,BAY-869766,inhibit,Inhibitor,MAP2K,MEK2,orally,MAPKK,RDEA-119,Mi
Refametinib (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).
价 格：￥电议型 号：T6636产 地：中国大陆
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T8405Vardenafil hydrochloridePDE-5 inhibitors,Vardenafil,Endogenous Metabolite,diabetes,Zucker diabetic f
Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes
价 格：￥电议型 号：T8405产 地：中国大陆
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TN1712GossypinAntiinflammatory,inhibit,Nuclear factor-κB,Gossypin,Inhibitor,Antioxidant,Anticancer,cardiov
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role in the suppression of inflammation, carcinogenesis, and angiogenesis.
价 格：￥电议型 号：TN1712产 地：中国大陆
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T8581Flecainide hydrochlorideNa channels,fetal tachycardias,Potassium Channel,orally active,Inhibitor,Sod
Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.
价 格：￥电议型 号：T8581产 地：中国大陆
