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TN6490Regaloside Canti-inflammatory,inhibit,Cardiovascular disease,H9C2,anti-depression,glycoside,diabetic
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
价 格:¥电议型 号:TN6490产 地:中国大陆
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T8005Cardiogenol C hydrochlorideInhibitor,β-catenin,plasticity,Cardiomyogenic,MHC,Wnt,inhibit,pyrimidine,
Cardiogenol C hydrochloride can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
价 格:¥电议型 号:T8005产 地:中国大陆
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T9618HeE1-2TyrHeE12Tyr,Nile,West,SARS-CoV,HeE1 2Tyr,SARS coronavirus,RdRp,HeE1-2Tyr,inhibit,HeE-1-2Tyr,fl
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 ?M) activity in vitro.
价 格:¥电议型 号:T9618产 地:中国大陆
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T9999Benzamide, N-(3-imidazo[2,1-b]thiazol-6-ylphenyl)-2-methoxySirtuin modulator-2,cardiovascular diseas
Benzamide, N-(3-imidazo[2,1-b]thiazol-6-ylphenyl)-2-methoxy exhibits antidiabetic, anti-inflammatory and antitumor activities.
价 格:¥电议型 号:T9999产 地:中国大陆
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T7805GW791343 dihydrochlorideinhibit,depressive disorder,Inhibitor,P2X Receptor,neurological disease,ATP,
GW791343 dihydrochloride is a P2X7 allosteric modulator.
价 格:¥电议型 号:T7805产 地:中国大陆
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T8786VUT-MK142Inhibitor,repair,VUT-MK142,mesoderm,VUT-MK-142,cardiac,cardiomyocyte,inhibit,VUTMK142,VUT M
VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.
价 格:¥电议型 号:T8786产 地:中国大陆
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T9491PyraclostrobinInhibitor,Mitochondrial toxicity,Pyraclostrobin,obesity,Fungal,cardiovascular,Bacteria
Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.
价 格:¥电议型 号:T9491产 地:中国大陆
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T8820BML-284 hydrochlorideBML284 hydrochloride,AGS,TCF,N-cadherin,Wnt,BML284,cardiac defect,MNK45,BML 284
BML-284 HCL is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
价 格:¥电议型 号:T8820产 地:中国大陆
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T6S0721Orientinneuroprotective,inhibit,Inhibitor,cardio,protection,Orientin
1. Orientin may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive defi
价 格:¥电议型 号:T6S0721产 地:中国大陆
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T8441Lerisetron5-HT Receptor,Serotonin Receptor,Serotonin,Lerisetron,Bradycardia,Inhibitor,5-hydroxytrypt
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.
价 格:¥电议型 号:T8441产 地:中国大陆
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T6104Cerdulatinib hydrochloridePRT 062070,PRT 2070,Inhibitor,malignancies,Tyk2,Cerdulatinib hydrochloride
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
价 格:¥电议型 号:T6104产 地:中国大陆
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T8388VonoprazanTAK-438,TAK 438,GERD,TAK438,Bacterial,antisecretory,blocker,peptic,Proton Pump,secretion,i
Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis
价 格:¥电议型 号:T8388产 地:中国大陆
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T6S1740Nardosinonecells,Nardosinone,Neurite,substances,PC12D,outgrowth-promoting,neuritogenic,inhibit,MAPK,
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and stau
价 格:¥电议型 号:T6S1740产 地:中国大陆
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T32191Irdabisant
Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant exhibits relatively low inhibitory activity against hERG current (IC50= 13.8 μM). Irdabisant exhibits cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used for research on schizophrenia or cognitive impairment.
价 格:¥电议型 号:T32191产 地:中国大陆
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T9232Mitochondrial fusion promoter M1Mitochondrial Metabolism,ischemia,cardiac,inhibit,brain,damage,injur
Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates brain and cardiac damage in rats with cardiac ischemia/reperfusion injury.
价 格:¥电议型 号:T9232产 地:中国大陆
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TP1844LSmall Cardioactive Peptide B SCPB acetateSmall Cardioactive Peptide B SCPB acetate
Small Cardioactive Peptide B (SCPB) acetate is a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively.
价 格:¥电议型 号:TP1844L产 地:中国大陆
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T7212Delavirdine mesylatepolymerase,BHAP-U 90152,U90152,U 90152,Inhibitor,Reverse Transcriptase,Delavirdi
Delavirdine (mesylate) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
价 格:¥电议型 号:T7212产 地:中国大陆
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T9920EvolocumabAMG-145,Ser/Thr Protease,Repatha,AMG 145,inhibit,atherosclerotic cardiovascular disease,Se
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9).
价 格:¥电议型 号:T9920产 地:中国大陆
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TP1264Prolylleucinedisorders,Inhibitor,Prolylleucine,circadian,inhibit,motility,brain ,systems,peptidergic
Prolylleucine is a dipeptide containing branched-chain amino acids.
价 格:¥电议型 号:TP1264产 地:中国大陆