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T0245RS 61443吗替麦考酚酯;TM-MMF;Mycophenolate mofetil;RS61443
RS 61443 is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)
价 格:¥电议型 号:T0245产 地:中国大陆
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T0245Mycophenolate mofetilMycophenolate mofetil,RS61443,
Mycophenolate mofetil, an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
价 格:¥电议型 号:T0245产 地:美洲
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T1752NS6180NS6180
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
价 格:¥电议型 号:T1752产 地:美洲
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T2248AS-605240AS-605240,AS605240,AS 605240
AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).
价 格:¥电议型 号:T2248产 地:美洲
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T4654SLV319SLV319,(±)-BMS6462,(±)-Ibipinabant
SLV319 has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
价 格:¥电议型 号:T4654产 地:美洲
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T4665BMS626529BMS626529,Temsavir,
BMS-626529 is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
价 格:¥电议型 号:T4665产 地:美洲
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T6394AS-604850AS-604850,AS604850,AS 604850
AS-604850 is a specific and ATP-competitive PI3Kγ inhibitor (IC50: 250 nM), 18-fold more selective for PI3Kγ than PI3Kα, and over 80-fold selectivity for PI3Kγ than PI3Kδ/β.
价 格:¥电议型 号:T6394产 地:美洲
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T8843APS6-45;化合物APS6-45APS6-45
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
价 格:¥电议型 号:T8843产 地:中国大陆
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T8661AS601245.2TFA (345987-15-7 free base);化合物AS601245.2TFAAS601245.2TFA;AS601245.2TFA
AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respectively).
价 格:¥电议型 号:T8661产 地:中国大陆
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T81747MS6105;化合物 MS6105MS6105
MS6105 is a chimeric LDH protein hydrolysis-targeted PROTAC that degrades LDHA and LDHB efficiently, with its activity contingent on both time and the ubiquitin-proteasome system, exhibiting anticancer properties [1]. Additionally, as a click chemistry reagent possessing an Alkyne group, MS6105 can partake in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Azide-bearing molecules.
价 格:¥电议型 号:T81747产 地:中国大陆
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T81231S6 peptide;化合物 S6 peptideS6 peptide
S6 peptide, a lamin kinase of potential importance, plays a role in the induction of cardiac hypertrophy following mechanical loading and can be activated by various growth factors [1].
价 格:¥电议型 号:T81231产 地:中国大陆
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T79871S6K2-IN-1;化合物 S6K2-IN-1S6K2-IN-1
S6K2-IN-1 (Compound 2) is an inhibitor of S6K2 with an IC50 of 22 nM and also exhibits inhibitory activity against FGFR4 with an IC50 of 216 nM. This compound demonstrates acceptable stability in mouse liver microsomes [1].
价 格:¥电议型 号:T79871产 地:中国大陆
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T78154CS640;化合物 CS640CS640
CS640 is a selective calmodulin-dependent kinase inhibitor, targeting multiple isoforms, namely CaMK1D, CaMK1B, CaMK1A, CaMK1G, PIP5K1C, MEK5, RIPK4, and MLK3, with respective IC50 values of 0.08, 0.03, 0.001, 0.001, 11.2, 0.025, 5.69, and 2.75 μM. Additionally, CS640 exhibits inhibitory properties toward CYP450 enzymes 2C9 and 2C19 with IC50 values of 6 and 10 μM, correspondingly [1].
价 格:¥电议型 号:T78154产 地:中国大陆
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T77364Sibeprenlimab;Sibeprenlimab单抗VIS649|||VIS-649;VIS649|||VIS-649
Sibeprenlimab (VIS649) is a humanized IgG 2 monoclonal antibody that suppresses APRIL. Sibeprenlimab has an inhibitory effect on APRIL and may be studied for the prevention and treatment of kidney disease (IgAN).
价 格:¥电议型 号:T77364产 地:中国大陆
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T76633(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin;化合物 (Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-
(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin, a potent vasopressin V1 receptor (VP V1R) antagonist, significantly lowers mean arterial pressure (MAP) in rats [1].
价 格:¥电议型 号:T76633产 地:中国大陆
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T76612(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide;化合物 (D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatosta
´(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) is a somatostatin analogue exhibiting varying affinity for somatostatin receptors, with dissociation constants (Kd) of 0.61 nM for SSTR5, 11.05 nM for SSTR3, 23.5 nM for SSTR2, 1200 nM for SSTR1, and >1000 nM for SSTR4, respectively [1].´
价 格:¥电议型 号:T76612产 地:中国大陆
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T76595(Des-His6)-ACTH (1-24) (human, bovine, rat);化合物 (Des-His6)-ACTH (1-24) (human, bovine, rat)(Des-His6
(Des-His^6)-ACTH (1-24) (human, bovine, rat) is an adrenocorticotropic hormone (ACTH) analog. Produced by the anterior pituitary gland, ACTH is a polypeptide tropic hormone that regulates the production of cortisol and androgens [1].
价 格:¥电议型 号:T76595产 地:中国大陆
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T76348[D-Lys6]-LH-RH;化合物 [D-Lys6]-LH-RH[D-Lys6]-LH-RH
[D-Lys6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, serves as a GnRH receptor agonist [1].
价 格:¥电议型 号:T76348产 地:中国大陆
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T76302[Lys4] Sarafotoxin S6c;化合物 [Lys4] Sarafotoxin S6c[Lys4] Sarafotoxin S6c
[Lys4] Sarafotoxin S6c, an analogue of sarafotoxin, serves as a potent, partial agonist of the endothelin receptor, inducing contraction in pig coronary artery with an effective concentration (EC 50) of 1.5 nM [1].
价 格:¥电议型 号:T76302产 地:中国大陆
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T75807Sarafotoxin S6a TFA;化合物 Sarafotoxin S6a TFASarafotoxin S6a TFA
Sarafotoxin S6a TFA, an analogue of sarafotoxin, functions as an endothelin receptor agonist with an ET_A/ET_B selectivity profile akin to Endothelin-3. It demonstrates an EC_50 of 7.5 nM in stimulating the pig coronary artery [1].
价 格:¥电议型 号:T75807产 地:中国大陆