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T73132DS69910557;化合物 DS69910557DS69910557
DS69910557, a potent, selective, and orally active antagonist of the human parathyroid hormone receptor 1 (hPTHR1), exhibits antagonistic activity with an IC50 value of 0.08 μM. It is useful in researching hyperparathyroidism, hypercalcemia of malignancy, and osteoporosis.
价 格:¥电议型 号:T73132产 地:中国大陆
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T71422S6821;化合物 S6821S6821
S6821 is a TAS2R8 antagonist. S6821 was not found to be mutagenic or clastogenic in vitro, and did not induce micronuclei in bone marrow polychromatic erythrocytes in vivo.
价 格:¥电议型 号:T71422产 地:中国大陆
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T69365HMS607P03;化合物 HMS607P03HMS607P03
HMS607P03 is an activator of SIRT1 which induces autophagic cell death via the AMPK-mTOR-ULK complex and induces mitophagy by the SIRT1-PINK1-Parkin pathway. HMS607P03 downregulates 14-3-3γ, catalase, profilin-1, and HSP90α.
价 格:¥电议型 号:T69365产 地:中国大陆
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T6394AS-604850化合物AS6048505-[(2,2-二氟-1,3-苯并二恶茂-5-基)亚甲基]噻唑烷-2,4-二酮
AS-604850 is a specific and ATP-competitive PI3Kγ inhibitor (IC50: 250 nM), 18-fold more selective for PI3Kγ than PI3Kα, and over 80-fold selectivity for PI3Kγ than PI3Kδ/β.
价 格:¥电议型 号:T6394产 地:中国大陆
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T61898RS6212;化合物 RS6212RS6212
RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M)。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.
价 格:¥电议型 号:T61898产 地:中国大陆
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T5532BMS-687453;化合物BMS-687453BMS-687453|||PPAR|||BMS687453|||Peroxisome proliferator-activated receptors|
BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.
价 格:¥电议型 号:T5532产 地:中国大陆
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T5346S63845;化合物S63845S63845
S63845 is a selective MCL-1 inhibitor(Kd: 0.19 nM)
价 格:¥电议型 号:T5346产 地:中国大陆
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T4667EOS-62062化合物 T4667EOS 62062|||EOS62062|||EOS-62062
Pesampator (PF-04958242) is a potent, highly selective positive allosteric modulator of the AMPA receptor, also known as an AMPA potentiator, demonstrating an EC50 of 310 nM and a Ki of 170 nM [1].
价 格:¥电议型 号:T4667产 地:中国大陆
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T4665Temsavir;化合物BMS626529BMS626529;BMS626529
Temsavir (BMS626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
价 格:¥电议型 号:T4665产 地:中国大陆
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T4654(±)-Ibipinabant;化合物SLV319(±)-BMS6462|||SLV319|||(±)-SLV319;(±)-BMS6462|||SLV319|||(±)-SLV319
(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
价 格:¥电议型 号:T4654产 地:中国大陆
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T40070S65487 sulfateS65487 sulfateVOB560 sulfate
S65487 (VOB560) sulfate, a potent and selective Bcl-2 inhibitor, demonstrates activity against BCL-2 mutations, including G101V and D103Y. It exhibits poor affinity for MCL-1, BFL-1, and BCL-XL. Additionally, S65487 sulfate induces apoptosis and possesses anticancer activities.
价 格:¥电议型 号:T40070产 地:中国大陆
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T39976MS67;MS67MS67
MS67 is a potent and selective degrader of the WD40 repeat domain protein 5 (WDR5) with a dissociation constant (Kd) of 63 nM. It exhibits no activity against protein methyltransferases, kinases, G-protein-coupled receptors (GPCRs), ion channels, and transporters. Notably, MS67 demonstrates significant anticancer properties.
价 格:¥电议型 号:T39976产 地:中国大陆
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T39551S62798S62798S62798
S62798 is a highly potent and selective compound that inhibits activated thrombin activatable fibrinolysis inhibitor (TAFIa) with an IC50 value of 6 mM.
价 格:¥电议型 号:T39551产 地:中国大陆
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T39135S65487 hydrochloride;S65487 hydrochlorideS65487 hydrochloride|||VOB560 hydrochloride;S65487 hydrochl
S65487 (VOB560) hydrochloride, a potent and selective Bcl-2 inhibitor, is effective against BCL-2 mutations, including G101V and D103Y. It exhibits poor affinity for MCL-1, BFL-1, and BCL-XL. This compound induces apoptosis and possesses anticancer activities.
价 格:¥电议型 号:T39135产 地:中国大陆
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T384406-Maleimidocaproic acid sulfo-NHS;6-Maleimidocaproic acid sulfo-NHS6-Maleimidocaproic acid sulfo-NHS
6-Maleimidocaproic acid sulfo-NHS serves as an alkyl/ether-based PROTAC linker, facilitating the synthesis of PROTACs.
价 格:¥电议型 号:T38440产 地:中国大陆
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T36897S65487;S65487S65487
S65487 (VOB560) is a potent and selective Bcl-2 inhibitor. S65487 is also active on BCL-2 mutations, such as G101V and D103Y. S65487 has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 induces apoptosis and has anticaner activities[1][2].
价 格:¥电议型 号:T36897产 地:中国大陆
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T35210Xyloxemine;化合物 T35210BS6748|||BS-6748|||BS 6748;BS6748|||BS-6748|||BS 6748
Xyloxemine is a biochemical.
价 格:¥电议型 号:T35210产 地:中国大陆
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T35154Xanoxate sodium;化合物 T35154RS-6818|||RS6818|||RS 6818;RS-6818|||RS6818|||RS 6818
Xanoxate sodium is a biochemical.
价 格:¥电议型 号:T35154产 地:中国大陆
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T34479S6716;化合物 T34479S-6716|||S 6716;S-6716|||S 6716
S6716 is a bioactive chemical.
价 格:¥电议型 号:T34479产 地:中国大陆
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T34415RS 64459-193;化合物 T34415RS64459-193|||RS-64459-193;RS64459-193|||RS-64459-193
RS 64459-193 has a high affinity for the 5-HT1A binding site.
价 格:¥电议型 号:T34415产 地:中国大陆