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T9014SKI-178resistant,SphK,cytotoxic,myeloid,Inhibitor,Apoptosis,leukemia,multi-drug,inhibit,SKI-178,canc
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1.
价 格：￥电议型 号：T9014产 地：中国大陆
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T60205(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide(2S)4biphenyl4ylNhydroxy2methyl2
(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide is a LpxC inhibitor with IC50 >95.2 nM.
价 格：￥电议型 号：T60205产 地：中国大陆
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T7336ICA-121431Nav,Na channels,inhibitor,ICA-121431,ICA 121431,TTX-resistant,Sodium Channel,channel,Na+ c
ICA-121431 is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels.
价 格：￥电议型 号：T7336产 地：中国大陆
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TL0006Cichoric Acidp-Akt,inhibit,ROS,anti-inflammatory,Apoptosis,glucose uptake,insulin resistance,glucosa
Chicoric Acid is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and independent.
价 格：￥电议型 号：TL0006产 地：中国大陆
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T74564-Ethyloctanoic acid4-Ethyloctanoic acid,4Ethyloctanoic acid,inhibit,4 Ethyloctanoic acid,Inhibitor
4-Ethyloctanoic acid is a natural product isolated from Saussurea lappa Clarke,acts as food additive,Industrial perfume,and so on.
价 格：￥电议型 号：T7456产 地：中国大陆
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TQ0308CastanospermineCastanospermine,inhibit,Inhibitor,Glucosidase
Castanospermine is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l.
价 格：￥电议型 号：TQ0308产 地：中国大陆
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T9072TuxobertinibTuxobertinib,inhibit,ErbB-1,EGFR,BDTX 189,BDTX189,mutants,Epidermal growth factor recept
BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.
价 格：￥电议型 号：T9072产 地：中国大陆
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T8933JNJ-63576253 free baseJNJ 63576253 free base,resistant,TRC 253,JNJ63576253,TRC-253,CRPC,JNJ63576253
JNJ-63576253 is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC).
价 格：￥电议型 号：T8933产 地：中国大陆
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T25253Cinnamtannin B-1
Cinnamtannin B1 is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum zeylanicum, and Lindera umbellata. It is a potent antioxidant and protective agent against oxidative stress and apoptosis in human platelets. It is a Cox-2 inhibitor.
价 格：￥电议型 号：T25253产 地：中国大陆
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T6670Silymarinthistle,angiogenesis,Inhibitor,hepatocellular,resistance,SARS coronavirus,chemopreventive,i
Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
价 格：￥电议型 号：T6670产 地：中国大陆
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T6410Bexarotenecutaneous,lymphoma,selective,?retinoid,inhibit,Retinoic acid receptors,antineoplastic,T-ce
Bexarotene is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
价 格：￥电议型 号：T6410产 地：中国大陆
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T9179CLP-3094LNCaP,Inhibitor,Androgen Receptor,CLP3094,inhibit,prostate,CLP 3094,resistance,CLP-3094,anti
CLP-3094 is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selective and potent GPR142 antagonist.
价 格：￥电议型 号：T9179产 地：中国大陆
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TP1158Copper tripeptidehuman plasma,Copper tripeptide,inhibit,chemoattractant,fibroblast,endothelial,prote
Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine.
价 格：￥电议型 号：TP1158产 地：中国大陆
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T60122AldometanibCompoundIA47
Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib prevents FBP from binding to v-ATPase-associated aldolase and activates lysosomal AMPK. Aldometanib can be used for the research of metabolic homeostasis [1].
价 格：￥电议型 号：T60122产 地：中国大陆
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TP1862L[Sar9] Substance P acetate(77128-75-7 free base)[Sar9] Substance P acetate(77128 75 7 free base),[Sa
[Sar9]-Substance P acetate is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
价 格：￥电议型 号：TP1862L产 地：中国大陆
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T3946Octanoic acidOctanoic acid,inhibit,Inhibitor,Endogenous Metabolite
Caprylic acid is found naturally in coconuts and breast milk. It is an oily liquid with a slightly unpleasant rancid taste that is minimally soluble in water. Caprylic acid is used commercially in the production of esters used in perfumery and also in the manufacture of dye.
价 格：￥电议型 号：T3946产 地：中国大陆
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T7412Tandospirone citrateSM3997,SM-3997,Tandospirone,Tandospirone citrate,Inhibitor,Serotonin Receptor,SM
Tandospirone citrate is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM)
价 格：￥电议型 号：T7412产 地：中国大陆
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T6602Naratriptan hydrochlorideNaratriptan hydrochloride,Inhibitor,GR-85548A,Naratriptan,5-HT Receptor,5-h
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulatio
价 格：￥电议型 号：T6602产 地：中国大陆
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T9320YK-3-237YK3237,inhibit,Sirtuin,p53,breast,cancer,triple-negative,mtp53,Mutant,TNBC,Inhibitor,deacety
YK-3-237 reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells carrying mtp53.
价 格：￥电议型 号：T9320产 地：中国大陆
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T9493DL-2-AMINOOCTANOIC ACIDDL2AMINOOCTANOIC ACID,DL 2 AMINOOCTANOIC ACID
DL-2-Aminooctanoic acid, also known as a-aminocaprylate or alpha-aminocaprylic acid, belongs to the class of organic compounds known as alpha-amino acids.
价 格：￥电议型 号：T9493产 地：中国大陆
