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产品数:86101
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T6S1740Nardosinonecells,Nardosinone,Neurite,substances,PC12D,outgrowth-promoting,neuritogenic,inhibit,MAPK,
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and stau
价 格:¥电议型 号:T6S1740产 地:中国大陆
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T82734,6-Dioxoheptanoic acidInhibitor,4,6-Dioxoheptanoic acid,inhibit,4,6Dioxoheptanoic acid,4,6 Dioxohep
4,6-Dioxoheptanoic acid acts as a potent inhibitor of heme biosynthesis.
价 格:¥电议型 号:T8273产 地:中国大陆
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T60076Oritinibpharmacodynamics,non-small cell lung cancer,EGFR-T790M,EGFR TKI,SH1028,Irreversible,mutant-s
Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.
价 格:¥电议型 号:T60076产 地:中国大陆
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T64338AKI603AKI603,Aurora Kinase,chronic,CML,leukemia,myeloid,inhibit,imatinib-resistant,Inhibitor
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].
价 格:¥电议型 号:T64338产 地:中国大陆
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TP1369L[Sar9,Met(O2)11]-Substance P acetate[Sar9,Met(O2)11]Substance P acetate,[Sar-9,Met(O2)11]-Substance
[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P acetate is the sole to produ
价 格:¥电议型 号:TP1369L产 地:中国大陆
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TN6833octanaloctanal,inhibit,Bacterial,Inhibitor,Endogenous Metabolite
octanal is a natural product with antioxidant and antimicrobial activities.
价 格:¥电议型 号:TN6833产 地:中国大陆
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TN6743ETHYL OCTANOATEETHYL OCTANOATE
ETHYL OCTANOATE is a natural product.
价 格:¥电议型 号:TN6743产 地:中国大陆
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T8121Octacosanoic acidOctacosanoic acid,Inhibitor,Endogenous Metabolite,Montanic acid,inhibit
Octacosanoic acid has antiplatelet and antithrombotic effects.
价 格:¥电议型 号:T8121产 地:中国大陆
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T9522RimtuzalcapKcsA,movement,small-conductance,channels,Rimtuzalcap,SK channels,CAD1883,CAD 1883,tremor,
Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels). Rimtuzalcap can be used for the research of movement disorders including spinocerebellar ataxia (SCA) and essential tremor (ET).
价 格:¥电议型 号:T9522产 地:中国大陆
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T9625SandaloreInhibitor,Apoptosis,Sandalore,IGF-1,spontaneous,olfactory receptor,hair growth,inhibit,foll
Sandalore prolongs human hair growth by decreasing apoptosis and increasing the production of the anagen-prolonging growth factor IGF-1 in the outer root sheath. Sandalore is a selective agonist of olfactory receptor OR2AT4.
价 格:¥电议型 号:T9625产 地:中国大陆
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T8666NaratriptanInhibitor,GR-85548A,5-hydroxytryptamine Receptor,inhibit,Serotonin Receptor,5-HT Receptor
Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.
价 格:¥电议型 号:T8666产 地:中国大陆
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T9304(S)-SunvozertinibHER1,Her2,(S)Sunvozertinib,mutant forms of ErbB,Epidermal growth factor receptor,(S
DZD9008 is a rationally designed selective, irreversible EGFR/HER2 inhibitor.
价 格:¥电议型 号:T9304产 地:中国大陆
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TP2322Lbeta-Neoendorphin acetate(77739-21-0 free base)betaNeoendorphin acetate(77739210 free base),beta Neo
beta-Neoendorphin acetate is an agonist of κ-opioid receptor
价 格:¥电议型 号:TP2322L产 地:中国大陆
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T7828[Sar9,Met(O2)11]-Substance PInhibitor,Tachykinin receptor,[Sar9,Met(O2)11]-Substance P,NK receptor,N
Bhsar-sp is an agonist of NK1 receptor.
价 格:¥电议型 号:T7828产 地:中国大陆
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T7589Afamelanotide acetateMelanotan,melanotropic peptide,Melanocortin Receptor,Afamelanotide acetate,skin
Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria.
价 格:¥电议型 号:T7589产 地:中国大陆
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T4404Methyl 2-(Boc-aMino)-2-(oxetan-3-yl)acetateMethyl 2 (Boc aMino) 2 (oxetan 3 yl)acetate,Methyl 2(Boca
Methyl 2-(Boc-aMino)-2-(oxetan-3-yl)acetate is a chemical compound.
价 格:¥电议型 号:T4404产 地:中国大陆
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T67857(Z)-4-(5-((5-(4-bromophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid
(Z)-4-(5-((5-(4-bromophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid is an ASK1 inhibitor, IC50 = 0.2 μM.
价 格:¥电议型 号:T67857产 地:中国大陆
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T40026Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-Butanoi
Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- is a Cereblon ligand with alkyl linker and terminal acid for onward chemistry.
价 格:¥电议型 号:T40026产 地:中国大陆
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T67848Valsartan Methyl Ester
Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
价 格:¥电议型 号:T67848产 地:中国大陆
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TQ0259AtrasentanAtrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627
Atrasentan (ABT-627) is an endothelin receptor antagonist (IC50: 0.0551 nM for ETA).
价 格:¥电议型 号:TQ0259产 地:中国大陆