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T72154Topoisomerase IV inhibitor 2；化合物 Topoisomerase IV inhibitor 2Topoisomerase IV inhibitor 2
Topoisomerase IV inhibitor 2 (compound 5d) is a potent inhibitor of DNA topoisomerase IV (TOPO IV), exhibiting IC50 values of 0.35 μM for TOPO IV and 0.55 μM for DNA gyrase. It also demonstrates antibacterial properties, with minimum inhibitory concentrations (MICs) of 1.985 μM against Staphylococcus aureus Newman and 0.744 μM against Escherichia coli ATCC8739 [1].
价 格：￥电议型 号：T72154产 地：中国大陆
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T72153Topoisomerase IV inhibitor 1；化合物 Topoisomerase IV inhibitor 1Topoisomerase IV inhibitor 1
Topoisomerase IV inhibitor 2 (compound 7d) is a potent inhibitor of DNA topoisomerase IV (TOPO IV), exhibiting IC50 values of 0.23 μM for TOPO IV and 0.43 μM for DNA gyrase. It also demonstrates antibacterial efficacy, with minimum inhibitory concentrations (MICs) of 0.972 μM against Staphylococcus aureus Newman and 0.608 μM against Escherichia coli ATCC8739 [1].
价 格：￥电议型 号：T72153产 地：中国大陆
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T67899Topoisomerase II inhibitor 13；化合物 Topoisomerase II inhibitor 13Topoisomerase II inhibitor 13
Topoisomerase II inhibitor 13 inhibits topoisomerase II (Topo II) that shows strong anti-proliferation activity against HL-60/MX2 cancer cells derived from HL-60 against Topo II toxicity.
价 格：￥电议型 号：T67899产 地：中国大陆
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T64164Topoisomerase II inhibitor 11；化合物 Topoisomerase II inhibitor 11Topoisomerase II inhibitor 11
Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM). Topoisomerase II inhibitor 11 inhibits cell proliferation and has apoptotic activity by blocking the cell cycle in the G2/M phase.
价 格：￥电议型 号：T64164产 地：中国大陆
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T64047Topoisomerase II inhibitor 10；化合物 Topoisomerase II inhibitor 10Topoisomerase II inhibitor 10
Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM). Topoisomerase II inhibitor 10 was able to arrest the cell cycle of HepG-2 cells in the G2-M phase and induce apoptosis.
价 格：￥电议型 号：T64047产 地：中国大陆
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T63594Topoisomerase IIα-IN-3；化合物 Topoisomerase IIα-IN-3Topoisomerase IIα-IN-3
Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.
价 格：￥电议型 号：T63594产 地：中国大陆
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T63526Topoisomerase I/II inhibitor 4；化合物 Topoisomerase I/II inhibitor 4Topoisomerase I/II inhibitor 4
Topoisomerase I/II inhibitor 4 is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) with inhibitory effects on cell proliferation, invasion and migration, and induction of apoptosis, and can be used to study hepatocellular carcinoma.
价 格：￥电议型 号：T63526产 地：中国大陆
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T63360DNA topoisomerase II inhibitor 1；化合物 DNA topoisomerase II inhibitor 1DNA topoisomerase II inhibitor
DNA topoisomerase II inhibitor 1 is a potent inhibitor of DNA topoisomerase II that arrests the cell cycle in sub-G1 phase and induces apoptosis with anti-value-added effects.
价 格：￥电议型 号：T63360产 地：中国大陆
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T63304Topoisomerase II inhibitor 9；化合物 Topoisomerase II inhibitor 9Topoisomerase II inhibitor 9
Topoisomerase II inhibitor 9 is a Topo II inhibitor (IC50: 0.97 μM) and DNA embedding agent (IC50: 43.51 μM) that blocks the Hep G-2 cell cycle in the G2/M phase and induces apoptosis.
价 格：￥电议型 号：T63304产 地：中国大陆
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T63068Topoisomerase II inhibitor 5；化合物 Topoisomerase II inhibitor 5Topoisomerase II inhibitor 5
Topoisomerase II inhibitor 5 (Compound E24) is a DNAtopoisomerase II inhibitor with anticancer effects.
价 格：￥电议型 号：T63068产 地：中国大陆
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T62887Topoisomerase II inhibitor 4；化合物 Topoisomerase II inhibitor 4Topoisomerase II inhibitor 4
Topoisomerase II inhibitor 4 (compound E17) is a potent inhibitor of topoisomerase II. Topoisomerase II inhibitor 4 has antitumour effects, blocking the cell cycle in the G2/M phase, inhibiting the proliferation of cancer cells and exhibiting cytotoxicity. It inhibits the proliferation of cancer cells and exhibits cytotoxicity.
价 格：￥电议型 号：T62887产 地：中国大陆
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T62225Topoisomerase I inhibitor 8；化合物 Topoisomerase I inhibitor 8Topoisomerase I inhibitor 8
Topoisomerase I inhibitor 8, a hexacyclic analogue of camptothecin, is also a potent inhibitor of topoisomerase I and is toxic to tumour cells.
价 格：￥电议型 号：T62225产 地：中国大陆
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T62224Topoisomerase IIα-IN-2；化合物 Topoisomerase IIα-IN-2Topoisomerase IIα-IN-2
Topoisomerase IIα-IN-2 (compound 5) is a DNA-binding ligands and a potent inhibitor of the topoisomerase TopoIIα. Topoisomerase IIα-IN-2 exhibits high anti-proliferative activity in human cancer cell lines. Topoisomerase IIα-IN-2 arrests the cell cycle of cancer cells in the G2/M phase and significantly induces DNA damage.
价 格：￥电议型 号：T62224产 地：中国大陆
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T62223Topoisomerase IIα-IN-1；化合物 Topoisomerase IIα-IN-1Topoisomerase IIα-IN-1
Topoisomerase IIα-IN-1 (compound 2) is a DNA-binding ligands and a potent inhibitor of TopoIIα, a topoisomerase. topoisomerase IIα-IN-1 shows good anti-proliferative effects on human cancer cell lines.
价 格：￥电议型 号：T62223产 地：中国大陆
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T62094Topoisomerase I inhibitor 6；化合物 Topoisomerase I inhibitor 6Topoisomerase I inhibitor 6
Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I that traps the DNA-Top1 cleavage complex and has low cytotoxicity in non-cancerous cell lines. Research value.
价 格：￥电议型 号：T62094产 地：中国大陆
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T62002Topoisomerase I inhibitor 7；化合物 Topoisomerase I inhibitor 7Topoisomerase I inhibitor 7
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants.
价 格：￥电议型 号：T62002产 地：中国大陆
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T61990Topoisomerase I/II inhibitor 3；化合物 Topoisomerase I/II inhibitor 3Topoisomerase I/II inhibitor 3
Topoisomerase I/II inhibitor 3 (compound 7) is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) . By inhibiting PI3K /Akt/mTOR signaling pathway, Topoisomerase I/II inhibitor 3 can inhibit cell proliferation, invasion and migration, and induce apoptosis . Topoisomerase I/II inhibitor 3 has research value in liver cancer.
价 格：￥电议型 号：T61990产 地：中国大陆
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T61717Topoisomerase I inhibitor 4；化合物 Topoisomerase I inhibitor 4Topoisomerase I inhibitor 4
Topoisomerase I inhibitor 4 (compound 7a) is a potent inhibitor of topoisomerase I activity. It effectively inhibits the proliferation of various cancer cell lines including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 μM, 2.09 μM, 1.56 μM, and 1.92 μM, respectively. Thus, Topoisomerase I inhibitor 4 holds promise for cancer research applications [1].
价 格：￥电议型 号：T61717产 地：中国大陆
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T61501Topoisomerase I inhibitor 5；化合物 Topoisomerase I inhibitor 5Topoisomerase I inhibitor 5
Topoisomerase I inhibitor 5 is an efficient inhibitor of topoisomerase I, with an IC50 value. It effectively disrupts DNA and inhibits the activity of topoisomerase I. Moreover, it can induce apoptosis in MCF-7 cells and arrest the cell cycle at the G1 phase. Topoisomerase I inhibitor 5 also exhibits potency in reversing P-gp-mediated resistance to Adriamycin [1].
价 格：￥电议型 号：T61501产 地：中国大陆
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T61431Topoisomerase IIα-IN-4；化合物 Topoisomerase IIα-IN-4Topoisomerase IIα-IN-4
Topoisomerase IIα-IN-4 (F2) is a non-intercalative ATP-competitive inhibitor of human DNA topoisomerase II, specifically inhibiting TopoIIα with an IC50 value of 3.8 μM and TopoIIβ with an IC50 value of 10.1 μM. It demonstrates significant efficacy in inducing apoptosis and arresting the cell cycle in HepG2 cells. Moreover, Topoisomerase IIα-IN-4 exhibits robust antitumor effects against various human cancer cell lines, making it a valuable compound for cancer research [1].
价 格：￥电议型 号：T61431产 地：中国大陆
