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T8412(S,R,S)-AHPC；化合物MDK7526VH032-NH2|||MDK7526|||VHL ligand 1；VH032-NH2|||MDK7526|||VHL ligand 1
(S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC is potential useful for the targeted degradation of the androgen receptor.
价 格：￥电议型 号：T8412产 地：中国大陆
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T83954VH 032 amide-alkylC7-acid；化合物 VH 032 amide-alkylC7-acid(S,R,S)-AHPC-amido-C7-acid；(S,R,S)-AHPC-amido
VH 032 amide-alkylC7-acid is a specialized compound designed for PROTAC research and development, serving as a functionalized von-Hippel-Lindau (VHL) protein ligand. It combines an E3 ligase ligand with an alkylC7 linker, ending in a terminal carboxylic acid for efficient conjugation to target protein ligands. This compound is among a series of functionalized tool molecules aimed at facilitating PROTAC R&D efforts.
价 格：￥电议型 号：T83954产 地：中国大陆
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T82928Azido-PEG2-VHL；化合物 Azido-PEG2-VHLAzido-PEG2-VHL
Azido-PEG2-VHL is a multikinase degrader utilized in PROTACs (PROteolysis TArgeting Chimeras) synthesis [1].
价 格：￥电议型 号：T82928产 地：中国大陆
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T80189Hainantoxin-IV；化合物 Hainantoxin-IVHNTX-IV；HNTX-IV
Hainantoxin-IV acts as a specific antagonist for tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels, with His28 and Lys32 being critical residues for binding to the target. This compound also features an inhibitor cystine knot motif [1].
价 格：￥电议型 号：T80189产 地：中国大陆
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T79720VHL-IN-1；化合物 VHL-IN-1VHL-IN-1
VHL-IN-1 (compound 30), a ubiquitin E3 ligase von Hippel-Lindau (VHL) inhibitor with a dissociation constant (Kd) of 37 nM, potently stabilizes HIF-1α and enhances its transcriptional activity. It shows promise for applications as a HIF-1α stabilizer and for the degradation of proteolytically targeted chimeras (PROTACs) [1].
价 格：￥电议型 号：T79720产 地：中国大陆
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T77916(S,R,S)-AHPC-Boc；化合物 (S,R,S)-AHPC-BocVH032-Boc；VH032-Boc
(S,R,S)-AHPC-Boc (VH032-Boc) serves as a ligand for the von Hippel-Lindau (VHL) protein recruitment in PROTAC technology [1].
价 格：￥电议型 号：T77916产 地：中国大陆
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T7752(S,R,S)-AHPC-Me；化合物(S,R,S)-AHPC-MeVHL ligand 2|||E3 ligase Ligand 1A；VHL ligand 2|||E3 ligase Ligand
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
价 格：￥电议型 号：T7752产 地：中国大陆
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T76511HIV Protease Substrate IV；化合物 HIV Protease Substrate IVHIV Protease Substrate IV
HIV Protease Substrate IV, a substrate for HIV (human immunodeficiency virus) protease, facilitates the measurement of HIV-1 protease activity [1].
价 格：￥电议型 号：T76511产 地：中国大陆
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T76080Human PD-L1 inhibitor V；化合物 Human PD-L1 inhibitor VHuman PD-L1 inhibitor V
Human PD-L1 Inhibitor V is a peptide that binds to the human PD-1 protein with an affinity characterized by a dissociation constant (Kd) of 3.32 μM, effectively inhibiting the hPD-1/hPD-L1 interaction [1].
价 格：￥电议型 号：T76080产 地：中国大陆
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T75835HSDVHK-NH2 TFA；化合物 HSDVHK-NH2 TFAHSDVHK-NH2 TFA
HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [2].
价 格：￥电议型 号：T75835产 地：中国大陆
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T4207(S,R,S)-AHPC hydrochloride；化合物Protein degrader 1 hydrochlorideVHL Ligand 1 hydrochloride|||ULM-1|||P
(S,R,S)-AHPC hydrochloride (Protein degrader 1 hydrochloride) is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
价 格：￥电议型 号：T4207产 地：中国大陆
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T41171BODIPY FL VH032；BODIPY FL VH032BODIPY FL VH032
BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of VHL ligands. BODIPY FL VH032 consists of a derivative of von Hippel-Lindau (VHL) ligand VH 032 and a fluorophore BODIPY FL(with excitation peak at 504 nm and emission peak at 520 nm), joined by a polyethylene glycol (PEG) 4 linker. The BODIPY FL VH032 VHL TR-FRET signal is stable
价 格：￥电议型 号：T41171产 地：中国大陆
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T41170cisVH 298；cisVH 298cisVH 298
cisVH 298 is a negative control for VH 298. Exhibits no detectable binding of VHL.
价 格：￥电议型 号：T41170产 地：中国大陆
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T39873(S,R,S)-AHPC-C8-NH2；(S,R,S)-AHPC-C8-NH2VH032-C8-NH2|||(S,R,S)-AHPC-C8-NH2；VH032-C8-NH2|||(S,R,S)-AHP
(S, R, S)-AHPC-C8-NH2 (VH032-C8-NH2) is an E3 ligase ligand-linker conjugate. This compound comprises the VH032-based VHL ligand and a linker, specifically designed for AKT PROTAC degrader applications.
价 格：￥电议型 号：T39873产 地：中国大陆
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T39838(S,R,S)-AHPC-C7-amine；(S,R,S)-AHPC-C7-amineVH032-C7-amine|||(S,R,S)-AHPC-C7-amine；VH032-C7-amine|||(
(S,R,S)-AHPC-C7-amine, also known as VH032-C7-amine, is a chemically synthesized conjugate that functions as an E3 ligase ligand-linker. This compound combines the VH032-based VHL ligand with a specific linker designed for the degradation of estrogen-related receptor α (ERRα) PROTAC.
价 格：￥电议型 号：T39838产 地：中国大陆
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T39735(S,R,S)-AHPC-PEG1-NH2；(S,R,S)-AHPC-PEG1-NH2VH032-PEG1-NH2|||(S,R,S)-AHPC-PEG1-NH2；VH032-PEG1-NH2|||(
(S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) is a synthesized conjugate combining the VH032-based VHL ligand with a linker designed for use in PROTAC technology, serving as an E3 ligase ligand-linker.
价 格：￥电议型 号：T39735产 地：中国大陆
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T39659(S,R,S)-AHPC-CO-C9-acid；(S,R,S)-AHPC-CO-C9-acidVH032-NH-CO-C9-acid|||(S,R,S)-AHPC-CO-C9-acid；VH032-N
(S,R,S)-AHPC-CO-C9-acid is a ligand-linker conjugate specifically designed to function as an E3 ligase ligand. This compound possesses the capability to be attached to a ligand, which enables the formation of PROTACs with proteins.
价 格：￥电议型 号：T39659产 地：中国大陆
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T39651(S,R,S)-AHPC-C5-NH2；(S,R,S)-AHPC-C5-NH2(S,R,S)-AHPC-C5-NH2|||VH032-C5-NH2；(S,R,S)-AHPC-C5-NH2|||VH03
(S,R,S)-AHPC-C5-NH2, also known as VH032-C5-NH2, is a synthetic compound designed as an E3 ligase ligand-linker conjugate. This compound combines the VH032-based von Hippel-Lindau (VHL) ligand with a linker, enabling it to function as a PROTAC degrader for estrogen-related receptor α (ERRα).
价 格：￥电议型 号：T39651产 地：中国大陆
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T39588Human PD-L1 inhibitor IV；Human PD-L1 inhibitor IVHuman PD-L1 inhibitor IV；Human PD-L1 inhibitor IV
Human PD-L1 inhibitor IV is a polypeptide compound that competitively inhibits the human PD-1 protein. It has a Kd value of 1.38 μM and effectively blocks the interaction between hPD-1 and hPD-L1.
价 格：￥电议型 号：T39588产 地：中国大陆
