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T35479CRBN-6-5-5-VHL；CRBN-6-5-5-VHLCRBN-6-5-5-VHL
Potent and selective cereblon degrader (DC50 = 1.5 nM). Induces complete degradation of cereblon in MM1S cells. Comprises a cereblon E3 ligase ligand joined by a linker to a ligand for the E3 ligase VHL. Cell-permeable.
价 格：￥电议型 号：T35479产 地：中国大陆
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T35478cis VH 032, amine dihydrochloride；顺式 VH 032, amine二盐酸盐(S,S,S)-AHPC；(S,S,S)-AHPC
cis VH 032, amine dihydrochloride ((S,S,S)-AHPC) is a negative control for the functionalized VHL ligand VH 032, amine .
价 格：￥电议型 号：T35478产 地：中国大陆
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T31808Flrlamide, manduca；化合物 T31808Glu-asp-val-val-his-ser-phe-leu-arg-phe-Nh2|||Pedvvhsflrf-NH2|||Masflrf
Flrlamide, manduca is a bioactive peptide extracted from the central nervous system of Manduca sexta.
价 格：￥电议型 号：T31808产 地：中国大陆
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T30576Brasofensine；化合物 T30576BMS-204756|||CID9554198|||BMS204756|||UNII-1YP2S94RVH|||BMS 204756；BMS-204756
Brasofensine is a monoamine reuptake blocker, which is a benztoalkane. In animal models of Parkinson´s disease, Brasofensine is effective in stimulating LMA and reversing motor inactivity. Brasofensine is being developed to treat Parkinson´s disease and Alzheimer´s disease.
价 格：￥电议型 号：T30576产 地：中国大陆
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T29106VH032；化合物VH032VH-032|||VH 032；VH-032|||VH 032
VH032 commonly used as a precursor to a PROTAC that hijacks VHL as the E3 ubiquitin ligase component.VH032 is a VHL/HIF-1α interaction inhibitor with a KdPROTACs, which can recruit von Hippel-Lindau (VHL) proteins as a ligand of VHL.
价 格：￥电议型 号：T29106产 地：中国大陆
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T18873VHL Ligand-Linker Conjugates 17；化合物 T18873VHL Ligand-Linker Conjugates 17
VHL Ligand-Linker Conjugates 17 are chemical compounds that consist of a VHL ligand specialized for the E3 ubiquitin ligase, as well as a PROTAC linker. These conjugates are utilized in the synthesis of various PROTACs, including the notable ARD-266. ARD-266 is an exceptionally effective androgen receptor (AR) PROTAC degrader[1].
价 格：￥电议型 号：T18873产 地：中国大陆
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T18872(S,R,S)-AHPC-PEG5-COOH；化合物 T18872VH032-PEG5-COOH|||E3 Ligase Ligand-Linker Conjugates 58|||VHL Ligan
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC based VHL ligand and a 5-unit PEG linker [1].
价 格：￥电议型 号：T18872产 地：中国大陆
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T18675(S,R,S)-AHPC-PEG2-NH2 dihydrochloride；(S,R,S)-AHPC-PEG2-NH2二盐酸盐VH032 amide-PEG2-amine|||VH032-PEG2-N
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker[1].
价 格：￥电议型 号：T18675产 地：中国大陆
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T18673(S,R,S)-AHPC-O-Ph-PEG1-NH2；化合物 T18673VH032-O-Ph-PEG1-NH2；VH032-O-Ph-PEG1-NH2
(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) serves as an E3 ligase ligand-linker conjugate, integrating a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is utilized in PROTAC EED degrader-1, a PROTAC that targets EED with a potency (pKD) of 9.02[1].
价 格：￥电议型 号：T18673产 地：中国大陆
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T18672(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc；化合物 T18672VH032-O-Ph-PEG1-NH-Boc；VH032-O-Ph-PEG1-NH-Boc
(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate, specifically designed for targeting the EED protein in PROTAC applications[1].
价 格：￥电议型 号：T18672产 地：中国大陆
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T18667(S,R,S)-AHPC-C5-COOH；化合物 T18667VH032-C5-COOH；VH032-C5-COOH
(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized conjugate designed for E3 ligase ligand-linker applications, combining the VH032 VHL-based ligand with a linker for PROTAC development. VH-032 acts as a selective and potent VHL/HIF-1α interaction inhibitor, with a dissociation constant (Kd) of 185 nM, offering potential in anemia and ischemic diseases research[1].
价 格：￥电议型 号：T18667产 地：中国大陆
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T18666(S,R,S)-AHPC-C4-NH2；化合物 T18666VH032-C4-NH2；VH032-C4-NH2
(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate of an E3 ligase ligand-linker, which combines the VHL ligand based on (S,R,S)-AHPC and a linker specifically designed for EED-Targeted PROTAC[1].
价 格：￥电议型 号：T18666产 地：中国大陆
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T18665(S,R,S)-AHPC-C4-NH2 dihydrochloride化合物 T18665VH032-C4-NH2 dihydrochloride
(S,R,S)-AHPC-C4-NH2 dihydrochloride is a chemically derived E3 ligase ligand-linker conjugate, consisting of the (S,R,S)-AHPC VHL ligand and a linker specifically designed for EED-Targeted PROTAC[1].
价 格：￥电议型 号：T18665产 地：中国大陆
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T18664(S,R,S)-AHPC-C3-NH2；化合物 T18664VH032-C3-NH2；VH032-C3-NH2
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in PROTAC technology. This compound serves as a key component in the synthesis of various PROTACs, including UNC6852. UNC6852 is a bivalent chemical degrader specifically targeting EED [1].
价 格：￥电议型 号：T18664产 地：中国大陆
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T18663(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base)；化合物 T18663(S,R,S)-AHPC-C3-NH2 TFA|||VH032-C3-NH2 TF
(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852. UNC6852 is an EED-targeted bivalent chemical degrader[1].
价 格：￥电议型 号：T18663产 地：中国大陆
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T18662(S,R,S)-AHPC-C2-PEG4-N3；化合物 T18662VH032-C2-PEG4-N3；VH032-C2-PEG4-N3
(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate combining the (S,R,S)-AHPC-based VHL ligand with a 4-unit polyethylene glycol (PEG) linker, employed in PROteolysis TAgeting Chimera (PROTAC) technology. This compound facilitates the creation of vRucaparib-TP4, a potent PARP1 degrader demonstrating a half-maximal degrading concentration (DC50) of 82 nM[1].
价 格：￥电议型 号：T18662产 地：中国大陆
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T18661(S,R,S)-AHPC-C10-NH2 dihydrochloride；(S,R,S)-AHPC-C10-NH2二盐酸盐VH032-C10-NH2 dihydrochloride|||VH032-l
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1].
价 格：￥电议型 号：T18661产 地：中国大陆
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T18640(S,R,S)-AHPC-C4-NH2 hydrochloride；化合物 (S,R,S)-AHPC-C4-NH2 hydrochlorideVH032-C4-NH2 hydrochloride|||
(S,R,S)-AHPC-C4-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 28) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
价 格：￥电议型 号：T18640产 地：中国大陆
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T18602VH032-thiol-C6-NH2；化合物 T18602VHL Ligand-Linker Conjugates 14|||E3 ligase Ligand-Linker Conjugates 29
VH032-thiol-C6-NH2, also known as VHL Ligand-Linker Conjugates 14, is a synthesized compound that functions as an E3 ligase ligand-linker conjugate. This compound combines the VH032 based VHL ligand with a linker commonly utilized in PROTAC technology.
价 格：￥电议型 号：T18602产 地：中国大陆
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T18600VH032 thiol；化合物 T18600VHL ligand 6；VHL ligand 6
VH032 thiol (VHL ligand 6) is a VHL ligand that interacts with pan-BET inhibitor JQ1 through a linker to create a PROTAC[1] compound.
价 格：￥电议型 号：T18600产 地：中国大陆
